
Puxico Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Ready to book your vacation to Puxico?
Puxico Hotel Deals

Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
CA $130
CA $145 total
Nov 1 - Nov 2
includes taxes & fees
9.4/10 Exceptional! (984 reviews)
"Our room was fine with new appliances. Creepy tv logo features your name. We did find the elevators were slow and noisy to the 4th floor. The pool was clean but not very big or deep. The gym was fine with satelite tv but there was a broken mirror. There was a 25$ charge when you walk in the door. ..."
Reviewed on Oct 13, 2026

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
CA $101
CA $113 total
Oct 15 - Oct 16
includes taxes & fees
8/10 Very good! (1,000 reviews)
"I only stayed here from midnight until 5:30. It was clean, however the bed was very thin and uncomfortable and the heat/ac didn't work correctly which happens sometimes. The thermostat said 75 and it was freezing. It was a good place to crash for a few hours."
Reviewed on Oct 11, 2026

Lake Wappapello
8005 Missouri 172 Williamsville MO
Fully refundableReserve now, pay when you stay
CA $128
CA $135 total
Oct 15 - Oct 16
includes taxes & fees
9.4/10 Exceptional! (6 reviews)
"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from ..."
Reviewed on Sep 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Puxico vacation package cost?
You can pick up a vacation package to this destination on Expedia. But how much your vacation to Puxico costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Puxico?
January, February and November are great times to look for cheap Puxico vacation packages. Choosing to travel in less busy months means you'll typically find reduced prices on flights and hotels.
How many days is enough for Puxico?
Generally, a handful of days is enough to tick off the major sights during your Puxico vacation. But if you'd like to have some time to relax or take day tours, consider extending your itinerary.
How to find the best Puxico package deals?
Use Expedia's filter tool to help you find some of the best Puxico package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for Puxico package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Puxico vacation as a package?
You can enjoy significant savings on your next Puxico escape by booking a personalized vacation package. Check the "Package" heading, then select your destination and travel dates to see some great airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Puxico?
If you've got your Puxico vacation dates confirmed, book as soon as you can to score some outstanding deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous getaways? Our last-minute deals are perfect for setting off on a whim.
How to plan a trip to Puxico?
- Pick the best time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to travel to Puxico.
- Set your budget: Consider expenses such as flights, food and transportation when calculating how much to save for your trip to Puxico. Then, pick a hotel that suits your budget, whether that's an affordable stay or a deluxe getaway.
- Decide how many days away: Start by making a list of all the attractions and activities you'd like to experience in Puxico. Then, estimate how long you'll need for each, including any travel time.
- Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left now is to choose a Puxico vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







