Title: Book The Best Hotels in Puxico, MO for 2025 from CA $74 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Puxico](https://expedia.ca/Puxico-Vacation-Rentals.d553248634983343452.Travel-Guide-VacationRentals)[Puxico Car Rentals](https://expedia.ca/Car-Rentals-In-Puxico.d553248634983343452.Car-Rental-Guide)[Puxico Vacation Packages](https://expedia.ca/Puxico.d553248634983343452.Destination-Travel-Guides) ![Great place for sunrises, Bald Eagles in the winter, and Milkyway shots. ](https://images.trvl-media.com/place/553248634983343452/de6c5278-53d4-4238-882c-19c2c1cec581.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mike McClain # Find hotels in Puxico, MO from CA $74 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Puxico Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America®ionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America®ionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America®ionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=PETS) ## Check prices for these dates Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983343452&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248634983343452&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248634983343452&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248634983343452&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 55 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/e921a7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/5904f90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/25677988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Poplar Bluff Poplar Bluff 9.4/10 Exceptional (764) "Nice place. Friendly staff." CA $135 CA $151 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/f3b3697d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/3f1c7b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/8fbe165c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Inn Dexter 6.8/10 (323) "Been a good stay every night" CA $84 CA $94 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/cc7b340b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/d71a605c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/bf46ac12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Poplar Bluff Poplar Bluff 9.4/10 Exceptional (813) "Very nice hotel! We had a great stay" CA $142 CA $161 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/59050052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/4ea0b11e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/874a4e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Poplar Bluff by IHG Poplar Bluff 8.8/10 Excellent (676) "Very clean and comfortable property close to dining options. Would definitely stay again " CA $135 CA $153 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/29f9134c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/84d95336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/a26934b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/49fa46e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Poplar Bluff Missouri Poplar Bluff 6.6/10 (606) "It was very nice, the staff was excellent, and the weather was great. " CA $82 CA $92 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/6497a67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/dcdd1977.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/59b72b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Dexter Dexter 6.8/10 (244) "Rough parking lot, sparse lobby, ok for one night on a trip, not a vacation spot" CA $77 CA $86 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b2d719b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/239bd50a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/a3a28e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Poplar Bluff Poplar Bluff 9.2/10 Wonderful (915) "Always a good stay" CA $131 CA $148 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8865f485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/eea0b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/f5deab1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Dexter Dexter 7.4/10 Good (370) "Currently the best option in Dexter. The upgrade from a couple of years ago is standing up to the wear and tear of the use." CA $93 CA $104 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/6388963b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/5b675ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchenette](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/476a2a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Poplar Bluff, MO Poplar Bluff 7.8/10 Good (1016) "Fantastic staff, cleaning crew and it was a wonderful experience." CA $110 CA $116 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/1db8fd06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/0c2f5a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/bac18eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/774fe752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Poplar Bluff North Poplar Bluff 7.8/10 Good (390) "Great breakfast Manager on duty very helpful with our questions." CA $120 CA $136 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Comfort-Inn-Poplar-Bluff-North.h79403.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/012f90a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/e8c32cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/02df00ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/21db18b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hickory House Inn Dexter 5.4/10 (125) "Nice room very comfortable bed's" CA $57 CA $74 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/a0829ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/5f50a8a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel Marble Hill 9.6/10 Exceptional (78) "Quiet small town vibe, great food and service! Definitely recommend " CA $147 CA $159 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/33adbe32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/4b3fbea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/0fce9903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/a0649327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Wappapello Williamsville CA $192 CA $203 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Williamsville-Hotels-Lake-Wappapello.h114278842.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn By Hilton Dexter Dexter CA $153 CA $172 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=553248634983343452&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPuxico-Hotels.d553248634983343452.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPuxico-Hotels.d553248634983343452.Travel-Guide-Hotels) ## More cheap stays in Puxico ![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Poplar Bluff, MO 4101 Highway 67 N, Poplar Bluff, MO CA $110 CA $116 total Sep 28 - Sep 29 includes taxes & fees 7.8/10 Good! (1,013 reviews) [](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Poplar Bluff 3109 Oak Grove, Poplar Bluff, MO CA $142 CA $161 total Oct 2 - Oct 3 includes taxes & fees 9.2/10 Wonderful! (810 reviews) [](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information) ![Hampton Inn Poplar Bluff](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Poplar Bluff 2420 Crestwood Dr, Poplar Bluff, MO CA $135 CA $151 total Oct 5 - Oct 6 includes taxes & fees 9.2/10 Wonderful! (764 reviews) [](https://expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ![Super 8 by Wyndham Poplar Bluff Missouri](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/29f9134c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Poplar Bluff Missouri 2831 N Westwood Blvd, Poplar Bluff, MO CA $82 CA $92 total Oct 5 - Oct 6 includes taxes & fees 6.4/10 (604 reviews) [](https://expedia.ca/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information) ![Econo Lodge Dexter](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/6497a67e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge Dexter 913 Outer Rd, Dexter, MO CA $77 CA $86 total Oct 26 - Oct 27 includes taxes & fees 6.6/10 (244 reviews) [](https://expedia.ca/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Travelodge by Wyndham Dexter](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Travelodge by Wyndham Dexter 1608 E Business US 60, Dexter, MO CA $93 CA $104 total Sep 28 - Sep 29 includes taxes & fees 7.4/10 Good! (368 reviews) [](https://expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ## Find out more about Puxico ### Top reasons to visit Puxico - **Outdoor Adventures:** Puxico is perfect for nature lovers, offering hiking trails and beautiful parks for exploration and relaxation. - **Romantic Getaways:** The charming atmosphere makes it an ideal spot for couples seeking a peaceful retreat. - **Arena Entertainment:** Visitors can enjoy various events and activities at the local arena, adding to the fun. - **Budget-Friendly Accommodations:** Puxico offers a range of comfortable hotels and motels to suit different budgets. - **Scenic Landscapes:** Highway 57 provides picturesque views, enhancing the travel experience in this quaint city. ### Find great hotels in Puxico Discover a variety of budget-friendly hotel accommodations in Puxico, Missouri, ranging from 2 to 2.5 stars. Ideal for both leisure and business travellers, the area features comfortable hotels and motels that cater to diverse needs, including pet-friendly options. Whether you're seeking a cozy place to relax or convenient amenities for work, Puxico has the perfect lodging for your visit. - **[Dexter Inn:](https://www.expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)** Located 22.5km from Puxico, Dexter Inn offers a charming retreat for pet lovers seeking a unique vacation experience. With a welcoming pet-friendly, this hotel allows certain pets onsite, ensuring that your furry friends can join in on the adventure. The property features a pet-friendly policy, including waived fees for service animals and specific restrictions applying to pets, primarily dogs and cats. Guests appreciate the warm ambiance and comfortable accommodations, making it a great choice for a relaxing getaway with pets. - **[Travelodge by Wyndham Dexter:](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information)** Also situated 22.5km from Puxico, Travelodge by Wyndham Dexter caters to both business and pet travellers. This hotel provides an array of business amenities, including a Business Centre and Meeting Room, making it ideal for professionals on the go. The pet-friendly allows dogs onsite, ensuring that you can balance work and leisure. With a pet-friendly policy featuring waived fees for service animals, this hotel is a practical option for those who want to blend business with the comfort of having their pets nearby. - **[Econo Lodge Dexter:](https://www.expedia.ca/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information)** Positioned 22.5km from Puxico, Econo Lodge Dexter offers a budget-friendly option with a focus on both business and pet accommodation. This motel supplies essential business services while ensuring a welcoming environment for guests traveling with pets. With a pet-policy that permits animals onsite and waived fees for service animals, guests can enjoy peace of mind during their stay. The Econo Lodge is an excellent choice for those seeking value without compromising on comfort and convenience. ### Where to stay in Puxico Puxico, Missouri, offers a charming blend of outdoor adventures and scenic beauty, making it ideal for romantic getaways or family-friendly vacations. Explore the quaint city and its welcoming atmosphere, while nearby attractions beckon with their unique experiences. From the picturesque landscapes along Highway 57 to the peaceful surroundings reminiscent of New Mexico or Puerto Rico, Puxico promises a memorable escape for every type of traveller. - **[Wappapello:](https://www.expedia.ca/Wappapello-Hotels.d183505.Travel-Guide-Hotels)** Located a mere 9.7km from Puxico, Wappapello is a charming city known for its stunning outdoor scenery and romantic atmosphere. Visitors are drawn to Wappapello primarily for its recreational opportunities, including access to a beautiful lake and the expansive Wappapello Lake State Park. The area boasts various entertainment options, such as an arena for events and outdoor activities that allow for exploration and relaxation amidst nature. The peak travel season from April to June offers the best experiences for those wanting to partake in outdoor adventures. - **[Fisk:](https://www.expedia.ca/Fisk-Hotels.d553248634983120615.Travel-Guide-Hotels)** Situated 19.3km from Puxico, Fisk is a delightful city that attracts visitors year-round, with a notable peak from June to August. Known for its scenic landscapes and outdoor activities, Fisk offers a variety of attractions including a local casino and a golf course for those looking to indulge in leisure activities. The nearby lake and national state park provide opportunities for hiking, fishing, and enjoying the natural beauty of the region. Fisk's vibrant atmosphere makes it an ideal destination for couples seeking romance while exploring the great outdoors. - **[Dudley:](https://www.expedia.ca/Dudley-Hotels.d553248634983299889.Travel-Guide-Hotels)** Also located 19.3km from Puxico, Dudley is a quaint city that offers a peaceful escape for nature lovers. With a focus on outdoor experiences, visitors can enjoy the local recreational areas that promote a variety of activities. Dudley is in proximity to a picturesque river and a visitor centre that provides insights into the area's natural beauty and attractions. The peak travel months from June to August see a rise in visitors looking to immerse themselves in the serene landscapes and romantic settings that Dudley has to offer. ### Things to do in Puxico Puxico, Missouri, is a charming destination perfect for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can explore a variety of activities, including enjoying the recreational area, experiencing the arena entertainment facility, and playing a round of golf. With its scenic landscapes and inviting atmosphere, Puxico offers a delightful escape for tourists looking to unwind and connect with nature. **Recreation** At [Ozark Ridge Golf Course](https://www.expedia.ca/Ozark-Ridge-Golf-Course-Hotels.0-l553248621554123001-0.Travel-Guide-Filter-Hotels), located 35.4km from Puxico, you can enjoy a scenic day on the greens while soaking up the outdoors. The course offers a relaxed atmosphere, perfect for both novice and seasoned golfers looking to unwind amidst nature. ### Booking tips and Expedia advantages for Puxico When visiting Puxico, Missouri, consider exploring free attractions like Lake Wappapello and Lake Wappapello State Park. To save on accommodation, plan your trip in February or November to December when prices are lower, and aim for a Wednesday stay, as Saturdays are the most expensive. Use Expedia to compare hotel prices and consider booking a package that combines your hotel, flights, and activities for additional savings. Lastly, keep an eye out for local discounts and competitive rates to make the most of your travel budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Puxico are February and November to December, where the prices are slightly lower. This is in comparison to April and June to July, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Puxico is Wednesday. The most expensive day to stay in Puxico is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to narrow down your options based on your budget, preferred location, and the type of accommodation you desire. To find the best prices and deals, simply adjust the price filter to sort from lowest to highest. - **Consider bundling your trip:** Consider saving some money by combining your Puxico hotel reservation with your flights and activities through an Expedia package. It's a smart way to get the most out of your travel experience! ### Find the best attractions in Puxico Puxico, Missouri, is an ideal destination for travellers seeking outdoor adventures and romantic getaways. The area boasts beautiful parks and nature reserves that offer eco-friendly experiences perfect for families. Whether you’re hiking through scenic landscapes or enjoying a leisurely stroll in the parks, Puxico provides a charming atmosphere for those looking to connect with nature and create lasting memories. - **Mingo Wilderness:** Located 4.8km from Puxico, Mingo Wilderness offers a serene escape into nature. Experience eco-friendly adventures through its scenic trails, where you can explore diverse wildlife and lush landscapes, perfect for hiking and birdwatching. - **Eagle Point Recreation Area:** Situated 11.3km away, Eagle Point Recreation Area is a family-friendly park boasting beautiful picnic spots and outdoor activities. Enjoy a day filled with hiking, fishing, or simply soaking up the eco-friendly atmosphere amidst stunning natural views. - **Spillway Recreation Area:** Also 11.3km from Puxico, Spillway Recreation Area is another excellent park for families. Engage in outdoor fun with trails, fishing opportunities, and a welcoming environment that connects you with nature. ### Best time to go to Puxico Visitor numbers in Puxico is generally unchanged in popularity throughout the year. The best time to visit Puxico is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 35.8°F (2.1°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | February | 38.8°F (3.8°C) | Light Rain | Mostly Sunny | Slightly High | Slightly Low | | March | 49.1°F (9.5°C) | Light Rain | Mostly Sunny | Average | Average | | April | 57.9°F (14.4°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 67.5°F (19.7°C) | Light Rain | Mostly Sunny | Average | Average | | June | 76.8°F (24.9°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | July | 79.7°F (26.5°C) | Light Rain | Mostly Sunny | Average | Slightly High | | August | 77.7°F (25.4°C) | Light Rain | Mostly Sunny | Average | Average | | September | 71.8°F (22.1°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | October | 60.3°F (15.7°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | November | 48.0°F (8.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 40.6°F (4.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | ### The nearest major airports for your trip to Puxico For your trip to Puxico, Missouri, you can fly into two major airports. Cape Girardeau Municipal Airport (CGI) is located 61.2km away, with hotel options like the Drury Plaza Hotel, Drury Inn & Suites, and Courtyard by Marriott, all situated within 9.7km. Alternatively, Cairo Regional Airport (CIR) is 83.7km from Puxico, offering nearby accommodations such as Quality Inn, Super 8 by Wyndham, and Eagle Inn, all within 17.7km. Both airports provide good access to Puxico and a range of transportation services to ensure a smooth journey. ## Recent reviews of Puxico hotels ![Dexter Inn](//images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d_y.jpg) ### Dexter Inn 5/5 Excellent "Been a good stay every night" A verified traveller stayed at Dexter Inn Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) ![Drury Inn & Suites Poplar Bluff](//images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164_y.jpg) ### Drury Inn & Suites Poplar Bluff 5/5 Excellent Weekend Getaway "The staff was very friendly. " A verified traveller stayed at Drury Inn & Suites Poplar Bluff Posted 6 days ago [](https://expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) ![Comfort Inn Poplar Bluff North](//images.trvl-media.com/lodging/1000000/80000/79500/79403/1db8fd06_y.jpg) ### Comfort Inn Poplar Bluff North 5/5 Excellent "Great breakfast Manager on duty very helpful with our questions." A verified traveller stayed at Comfort Inn Poplar Bluff North Posted 6 days ago [](https://expedia.ca/Poplar-Bluff-Hotels-Comfort-Inn-Poplar-Bluff-North.h79403.Hotel-Information) ![EC Reed's Mercantile and Hotel](//images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b_y.jpg) ### EC Reed's Mercantile and Hotel 5/5 Excellent "Quiet small town vibe, great food and service! Definitely recommend " A verified traveller stayed at EC Reed's Mercantile and Hotel Posted 6 days ago [](https://expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg) ### Motel 6 Poplar Bluff, MO 5/5 Excellent "Everything was great. I was traveling with 2 dogs. Everyone was great. I would only question the choice of the bathroom sink. Very unhandy. Otherwise a great value. " A verified traveller stayed at Motel 6 Poplar Bluff, MO Posted 6 days ago [](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Fairfield Inn & Suites by Marriott Poplar Bluff](//images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg) ### Fairfield Inn & Suites by Marriott Poplar Bluff 5/5 Excellent Great hotel "Very nice room. Check in was quick and clerk was friendly. The “continental” breakfast was the best one I’ve ever eaten. Only negative was they only had Apple juice for breakfast. Will definitely stay there again. " A verified traveller stayed at Fairfield Inn & Suites by Marriott Poplar Bluff Posted 7 days ago [](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information) ![Hampton Inn Poplar Bluff](//images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg) ### Hampton Inn Poplar Bluff 5/5 Excellent "Nice place. Friendly staff." A verified traveller stayed at Hampton Inn Poplar Bluff Posted 7 days ago [](https://expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ![Travelodge by Wyndham Dexter](//images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86_y.jpg) ### Travelodge by Wyndham Dexter 5/5 Excellent "Convenient " A verified traveller stayed at Travelodge by Wyndham Dexter Posted 2 weeks ago [](https://expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Private lake, beach & hot tub, romantic getaway or family vaca](//images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/c3950ef0_y.jpg) ### Private lake, beach & hot tub, romantic getaway or family vaca 5/5 Excellent "This was a perfect getaway for our honeymoon. It was nice and quiet and peaceful and just what we were looking for. We have found our close to home. We can get away spot. We definitely will be coming back again." A verified traveller stayed at Private lake, beach & hot tub, romantic getaway or family vaca Posted 1 month ago [](https://expedia.ca/Wappapello-Hotels-Private-Lake.h89711320.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Puxico hotel for you. ### How can I save on a Puxico hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Puxico hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Puxico hotel? > Prices for hotels in Puxico often vary, but you can find a great deal from CA $74 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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