A river, a large white building, and a cityscape.

Find Spa Hotels in Jackson, MO from CA $176

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Check availability on Jackson Spa Hotels

This weekend
Jul 3 - Jul 5
Next weekend
Jul 10 - Jul 12

Our top choices for Jackson hotels with a spa

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
The price is CA $156
CA $176 total
includes taxes & fees
Jul 16 - Jul 17
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Jackson

Pool
Breakfast included

Top Jackson Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Just a wonderful relaxing place to stay! Terrace on the 8th floor is a nice place to relax in the evening or with coffee in the morning!"
Scott 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently asked questions

Looking to vacation at a spa hotel in Jackson?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Enjoy the shopping and many popular restaurants during your vacation. Spa hotels are the perfect way to break out of your routine and add a layer of luxury to your weekend away.
What's there to see and do in Jackson?
Take in the sights and attractions that Jackson offers with a visit to Trail of Tears State Park, Mississippi River, and Lake Boutin. If you have a little extra time during your trip, you might want to check out Indian Creek Wild Area and Vancill Hollow Natural Area.
What is a Jackson spa hotel?
Spa hotels in Jackson provide lodging and have a full on-site spa which offers services including massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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