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Florida Keys Hotels

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Featured Florida Keys Spa Hotel

See all 330 Hotels in Florida Keys
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
4.0 out of 5.0
4.4 out of 5 (621 reviews)
Best location in KWGreat location for Duval St shops and Wharf resturaunts. We parked at the hotel and never needed the car. Great pool and beach area. Very quiet at night. Staff was wonderful. Will definitely stay here again.
  5 Jun 2017

C$371

C$371
Southernmost Beach Resort

Southernmost Beach Resort

508 South St, Key West
4.0 out of 5.0
4.5 out of 5 (1,376 reviews)
overall-OKNice hotel with a private beach, most of the staff struggle with speaking English. Very pricey!
  23 Jun 2017

C$339

C$339
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.0 out of 5.0
4.5 out of 5 (661 reviews)
Great hotel, right on the beach. Great hotel it is right on the beach. We can see the sunset every night from our room. Excellent combinations of bars restaurants, pool, Beach.
  30 May 2017

C$349

C$349
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
3.5 out of 5.0
4.1 out of 5 (159 reviews)
Not enough stars for this beautiful experience. Location is quiet, tropical, and calm. Within driving distance to numerous restaurants, shopping, recreation....or you may just stay and relax at the hotel grounds. Friendly staff, we did not want to leave. Definitely a return destination. Soon!
  1 Jun 2017

C$182

C$182
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Islamorada
4.0 out of 5.0
4.4 out of 5 (639 reviews)
The accommodations at Cheeca LodgeThe rooms were clean and the staff was friendly and always available to assist our needs.
  2 Jun 2017

C$326

C$326
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd, Duck Key
4.0 out of 5.0
4.2 out of 5 (1,121 reviews)
Nice hotel with very friendly staffWe have been to Hawks Cay twice and the best features for us is that there is an adults only pool. This is a good resort for families and there looks to be a lot of family activities. Alma is also an excellent restaurant and you can get Starbucks in the gift shop which we really appreciate!
  8 Jun 2017

C$323

C$323
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
3.5 out of 5.0
4.0 out of 5 (577 reviews)
Good stuff and comfortable room.The front desk Silvana was excellent... She upgraded us to a bigger room and with no cost... She was great..... I cant wait to go back to Miami Beach!!
  5 Jun 2017

C$258

C$258
Key Largo Bay Marriott Beach Resort

Key Largo Bay Marriott Beach Resort

103800 Overseas Hwy, Key Largo
3.5 out of 5.0
4.2 out of 5 (485 reviews)
It's the KeysLuxury in the keys is a little different than elsewhere. The Marriott remains one of the higher end spots and offers more than other "resorts" in the area. It is by far one of the largest hotels in the upper keys. Good dockage and location for boaters. Out of towners will find enough to do with on ...
  4 Jun 2017

C$230

C$230
The Cabana Inn Key West - Adult Exclusive

The Cabana Inn Key West - Adult Exclusive

413 Applerouth Lane, Key West
3.0 out of 5.0
4.6 out of 5 (268 reviews)
Great Location !Very cozy and comfortable hotel, we had a room for 5, 1 king, 1Queen and a twin bed, the location is great, restaurants and all kind of stores near by . Breakfast could be better if they can add some scramble eggs and sausages to it. Staff was very Friendly, they also have cheese and wine at ...
  5 Jun 2017

C$276

C$276
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West
3.0 out of 5.0
4.3 out of 5 (540 reviews)
On Anniversary #58. Staff was great couldn't do enough for everyone. Surprised with breakfast. Was better than some of the more expensive places we have stayed. Hotel very nice and just needs some work, but lovely atmosphere. The older style. Really enjoyed ourselves. Thank You Ronan and Michele for such a good ...
  17 May 2017

C$166

C$166
Map

Recently booked Florida Keys hotels

Casa Marina Resort - A Waldorf Astoria Resort
4.0 out of 5.0
Last booking: 12 minutes ago
Ocean Pointe Suites at Key Largo
3.5 out of 5.0
Last booking: 1 hour ago
Parrot Key Hotel & Resort
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Coconut Mallory Resort And Marina By Kees Vacations
3.0 out of 5.0
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Lime Tree Bay Resort
3.5 out of 5.0
Last booking: 1 hour ago
Smuggler's Cove Resort and Marina
2.5 out of 5.0
Last booking: 1 hour ago
Key Largo Bay Marriott Beach Resort
3.5 out of 5.0
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The Gates Hotel Key West
4.0 out of 5.0
Last booking: 1 hour ago
The Inn at Key West
3.5 out of 5.0
Last booking: 1 hour ago

Spa Hotel Guide in Florida Keys

When it comes to relaxation, there’s nothing like Florida Keys spa hotels. Unwind with a rejuvenating facial. Treat yourself to a Swedish massage. Melt stress away in the steamy sauna, or settle in for a sampling of the most high-tech treatments. Whether you’re looking for a quiet retreat or prefer to indulge in the most cutting-edge spa hotel near Florida Keys, the choices here are unbelievably tranquil.

It all starts with the personal check-in service, continues with the soothing rooms and gets even better with the dazzling array of made-for-you amenities. What’s more, many of the 330 spa hotels are situated near the best experiences and attractions, so you can uncover the area’s can’t-miss sights after a day of body scrubs, pedicures and facial masks.

Browse Expedia’s selection to find options that are close to your personal style, and then get ready to spend a long weekend — or an entire week — getting massaged, manicured and pampered beyond compare.