Title: 3 Stars Hotels in East Prairie, Missouri from CA $142 - Find Cheap East Prairie Hotels With 3 Stars | Expedia.ca [East Prairie Travel Guide](https://expedia.ca/East-Prairie.dx3000349349)[Hotels in East Prairie](https://expedia.ca/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Vacation Rentals in East Prairie](https://expedia.ca/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals)[Flights to East Prairie](https://expedia.ca/Cheap-Flights-To-East-Prairie.d3000349349.Travel-Guide-Flights)[East Prairie Car Rentals](https://expedia.ca/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide)[East Prairie Vacation Packages](https://expedia.ca/East-Prairie.d3000349349.Destination-Travel-Guides) ![Bridge over Mississippi River, New Orleans in background](https://images.trvl-media.com/place/6209928/57ec11c5-0aa9-4b04-9ae1-c121ec0bef56.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 3 Stars Hotels in East Prairie, Missouri from CA $142 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on East Prairie 3 Star Hotels Tonight [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-12-24&endDate=2025-12-25&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-12-25&endDate=2025-12-26&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=3000349349&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=30&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for East Prairie 3-star hotels ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1000) "This our favorite place to stop for a good night sleep. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eileen CA $123 CA $142 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.0/10 Wonderful (8) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $161 CA $183 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/120000000/119960000/119957500/119957421/2b668a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/120000000/119960000/119957500/119957421/164f8119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/120000000/119960000/119957500/119957421/36c832d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/120000000/119960000/119957500/119957421/57861912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prime Fishing & Boating: Tiptonville Home [](https://www.expedia.ca/Tiptonville-Hotels-Prime-Fishing-Boating-Tiptonville-Home.h119957421.Hotel-Information) Tiptonville [](https://www.expedia.ca/Tiptonville-Hotels-Prime-Fishing-Boating-Tiptonville-Home.h119957421.Hotel-Information) ![Family House, Multiple Beds](https://images.trvl-media.com/lodging/28000000/27920000/27918400/27918303/488dba0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | Private kitchen](https://images.trvl-media.com/lodging/28000000/27920000/27918400/27918303/cbc8dbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | Room amenity](https://images.trvl-media.com/lodging/28000000/27920000/27918400/27918303/469ea1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27920000/27918400/27918303/a24f1b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gloria's on Exchange [](https://www.expedia.ca/Union-City-Hotels-Glorias-On-Exchange.h27918303.Hotel-Information) Union City 10/10 Exceptional (2) "Love love love Gloria’s and love Julie and David they are the best hosts." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Union-City-Hotels-Glorias-On-Exchange.h27918303.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103020000/103019300/103019292/474cb1db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103020000/103019300/103019292/fbdeb3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103020000/103019300/103019292/759f3ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103020000/103019300/103019292/bd1a5710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boat Dock on Reelfoot Lake: Tiptonville Retreat [](https://www.expedia.ca/Tiptonville-Hotels-Tiptonville-Retreat-On-Reelfoot-Lake-W-Boat-Dock.h103019292.Hotel-Information) Tiptonville [](https://www.expedia.ca/Tiptonville-Hotels-Tiptonville-Retreat-On-Reelfoot-Lake-W-Boat-Dock.h103019292.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F3Star-East-Prairie-Hotels.s30-0-d3000349349.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F3Star-East-Prairie-Hotels.s30-0-d3000349349.Travel-Guide-Filter-Hotels) ## Learn more about East Prairie Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing. [See all hotels in East Prairie](https://www.expedia.ca/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08&adults=2®ionId=3000349349) ![Bridge over Mississippi River, New Orleans in background](https://images.trvl-media.com/place/6209928/57ec11c5-0aa9-4b04-9ae1-c121ec0bef56.jpg?impolicy=fcrop&w=900&h=292&p=1&q=high) ## Top East Prairie Hotel Reviews ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Everything was well done" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ## Find out more about East Prairie The top 3 Stars hotels in East Prairie, East Prairie may offer some of the best discounts and rates, but these properties are anything but average. Travelers love East Prairie 3 Stars hotels for their top quality services, just-like-home amenities, and wallet-friendly prices. You can even get access to fantastic perks like delectable restaurants, so-cool cocktail bars, and spacious fitness centres. Use the travel tools at Expedia.ca to find a cheap deal on a 3 Stars upscale hotel in East Prairie for a first-class experience, or book an inexpensive rate on one of the cheap 3 Stars hotels in East Prairie neighbourhoods near the city’s best attractions. We’ll even help you find vacation packages to go with your three star hotel in East Prairie. From last-minute work trips to long-awaited family getaways, we offer all the essentials you need to enjoy your jaunt through East Prairie. ## Frequently asked questions ### How much does it cost to stay in a 3-star hotel in East Prairie? > - Search for the lowest price per night right now from CA $142 ### What is the difference between a 4-star and 3-star hotel in East Prairie? ### What is the difference between a 3-star hotel and a motel in East Prairie? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [Apartments in Baker ](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City ](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Cheap-Hotels.0-0-d553248634983369680-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Benton ](https://www.expedia.ca/Benton-Hotels-Luxury-Hotel.0-0-d553248634983369680-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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