
Find hotels in East Prairie, MO from CA $88
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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is CA $123
CA $142 total
includes taxes & fees
Feb 11 - Feb 12

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (552 reviews)
The price is CA $74
CA $88 total
includes taxes & fees
Feb 8 - Feb 9

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (45 reviews)
The price is CA $89
CA $101 total
includes taxes & fees
Feb 7 - Feb 8

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (340 reviews)
The price is CA $110
CA $131 total
includes taxes & fees
Mar 8 - Mar 9

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (447 reviews)
The price is CA $137
CA $155 total
includes taxes & fees
Feb 13 - Feb 14

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (474 reviews)
The price is CA $133
CA $150 total
includes taxes & fees
Feb 28 - Mar 1

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (735 reviews)
The price is CA $80
CA $91 total
includes taxes & fees
Feb 9 - Feb 10

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (55 reviews)
The price is CA $138
CA $157 total
includes taxes & fees
Feb 19 - Feb 20

The Riverstone Hotel
The Riverstone HotelCharleston
6.8 out of 10, (408 reviews)
The price is CA $96
CA $106 total
includes taxes & fees
Feb 9 - Feb 10

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (739 reviews)

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (622 reviews)
The price is CA $85
CA $94 total
includes taxes & fees
Mar 9 - Mar 10

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,003 reviews)
The price is CA $117
CA $133 total
includes taxes & fees
Feb 22 - Feb 23

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (276 reviews)
The price is CA $93
CA $103 total
includes taxes & fees
Mar 6 - Mar 7

Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.6 out of 10, (122 reviews)
The price is CA $70
CA $84 total
includes taxes & fees
Mar 8 - Mar 9

Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHGUnion City
9.4 out of 10, Exceptional, (313 reviews)
The price is CA $145
CA $172 total
includes taxes & fees
Mar 8 - Mar 9

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
The price is CA $93
CA $106 total
includes taxes & fees
Feb 9 - Feb 10

Quality Inn Union City US 51
Quality Inn Union City US 51Union City
8.4 out of 10, Very good, (493 reviews)
The price is CA $92
CA $109 total
includes taxes & fees
Feb 22 - Feb 23

Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (170 reviews)
The price is CA $151
CA $179 total
includes taxes & fees
Feb 15 - Feb 16

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
The price is CA $87
CA $97 total
includes taxes & fees
Mar 9 - Mar 10

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very good, (286 reviews)
The price is CA $118
CA $134 total
includes taxes & fees
Feb 22 - Feb 23
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Fairfield Inn & Suites by Marriott Sikeston
10/10 Excellent
More cheap stays in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
The price is CA $80 per night from Feb 9 to Feb 10
CA $80
CA $91 total
Feb 9 - Feb 10
includes taxes & fees
8.4/10 Very Good! (733 reviews)
Hotels in East Prairie with star rating

3 Star Hotels
5 properties

2 Star Hotels
28 properties
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