Find hotels in East Prairie, MO from CA $91
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Sep 21 - Sep 22Tomorrow
Sep 22 - Sep 23This weekend
Sep 25 - Sep 27Next weekend
Oct 2 - Oct 4Our top choices for East Prairie hotels
1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Scott
CA $131
CA $151 total
includes taxes & fees
Sep 27 - Sep 28
2. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
Shelley
CA $122
CA $139 total
includes taxes & fees
Sep 27 - Sep 28
3. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
Jay
CA $93
CA $103 total
includes taxes & fees
Sep 24 - Sep 25
4. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
CA $141
CA $160 total
includes taxes & fees
Oct 4 - Oct 5
5. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Allen
CA $141
CA $160 total
includes taxes & fees
Sep 27 - Sep 28
6. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
William
CA $83
CA $92 total
includes taxes & fees
Sep 22 - Sep 23
7. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
John
CA $135
CA $153 total
includes taxes & fees
Sep 27 - Sep 28
8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
Sharika West
CA $87
CA $100 total
includes taxes & fees
Sep 24 - Sep 25
9. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
Hazlo
CA $93
CA $106 total
includes taxes & fees
Sep 24 - Sep 25
10. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
Stacy
CA $152
CA $173 total
includes taxes & fees
Oct 11 - Oct 12
11. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
Starlette
CA $124
CA $141 total
includes taxes & fees
Sep 27 - Sep 28
12. Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
Rachel
CA $81
CA $92 total
includes taxes & fees
Sep 23 - Sep 24
13. Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
William
CA $79
CA $94 total
includes taxes & fees
Oct 1 - Oct 2
14. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
Jackson
CA $108
CA $120 total
includes taxes & fees
Sep 22 - Sep 23
15. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
Santiago
CA $99
CA $110 total
includes taxes & fees
Oct 2 - Oct 3
16. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
William
CA $80
CA $91 total
includes taxes & fees
Sep 27 - Sep 28
17. Travel Inn Marston I-55 by Hotel O
Travel Inn Marston I-55 by Hotel OMarston
Frank
CA $62
CA $74 total
includes taxes & fees
Sep 22 - Sep 23
18. Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
Ben
CA $110
CA $130 total
includes taxes & fees
Oct 11 - Oct 12
19. Quality Inn Union City US 51
Quality Inn Union City US 51Union City
Trudy
CA $94
CA $112 total
includes taxes & fees
Oct 12 - Oct 13
20. Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
Jade
CA $84
CA $100 total
includes taxes & fees
Oct 8 - Oct 9
Stay near popular East Prairie attractions
Big Oak Tree State Park
8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.
See all hotels in East Prairie
Top East Prairie Hotel Reviews
Hampton Inn Union City
10/10 Excellent
"Clean room, friendly staff, good breakfast"
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Excellent hotel"
Quality Inn Union City US 51
10/10 Excellent
"Great stay for work. Really loved the hot tub."
Sleep Inn at Discovery Park of America
10/10 Excellent
"Great clean room and property!"
Hampton Inn Sikeston
10/10 Excellent
"Clean room not so friendly staff"
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
"The man at the front desk was very helpful and polite"
Holiday Inn Express & Suites Union City by IHG
8/10 Good
"Love the staff and the parking and the quiet"
The Riverstone Hotel Charleston-Sikeston
8/10 Good
"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8/10 Good
"Clean room. The front desk was very kind and helpful."
More cheap stays in East Prairie
Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
CA $80
CA $91 total
Sep 27 - Sep 28
includes taxes & fees
7/10 Good! (676 reviews)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
CA $87
CA $100 total
Sep 24 - Sep 25
includes taxes & fees
8.4/10 Very good! (821 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
CA $93
CA $106 total
Sep 24 - Sep 25
includes taxes & fees
7.2/10 Good! (1,006 reviews)
Sleep Inn at Discovery Park of America
1111 BLue Heron Lane Union City TN
CA $110
CA $130 total
Oct 11 - Oct 12
includes taxes & fees
9.2/10 Wonderful! (434 reviews)
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
CA $122
CA $139 total
Sep 27 - Sep 28
includes taxes & fees
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
CA $135
CA $153 total
Sep 27 - Sep 28
includes taxes & fees
9/10 Wonderful! (623 reviews)
Hotels in East Prairie with star rating
3 Star Hotels
6 properties
2 Star Hotels
25 properties
Frequently asked questions
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