East Prairie Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Ready to book your vacation to East Prairie?

 

Choose your dates

East Prairie Hotel Deals

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is CA $107 per night from Sep 4 to Sep 5
CA $107
CA $122 total
Sep 4 - Sep 5
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
"This property is very nice and clean.The only issue is need a better quality of bath tissue, but all places that we have stayed needs that lol"

Reviewed on Aug. 20, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is CA $116 per night from Sep 14 to Sep 15
CA $116
CA $133 total
Sep 14 - Sep 15
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
"The room i was in bathroom was horrible. Wall falling apart, tub nasty need tocbe replaced because i brought cleaning supplies and cleaned myself"

Reviewed on Aug. 22, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Sep 1 to Sep 2
CA $124
CA $143 total
Sep 1 - Sep 2
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
"The food options were great, the hotel was very clean, the staff were nice and friendly. The room was perfect and the bed was comfortable."

Reviewed on Aug. 18, 2025

Drury Inn & Suites Sikeston, MO
See all 80 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does an East Prairie vacation package cost?
You can grab a vacation package to this destination on Expedia. However, how much your vacation to East Prairie costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to East Prairie?
If you're looking to book a cheap East Prairie vacation package, consider visiting in January, February and November. You'll usually find lower prices on accommodations and flights during these quieter months — perfect for budget-conscious travellers.
How many days is enough for East Prairie?
With a well-organized itinerary, you can easily tick off the main East Prairie attractions in a handful of days. But if you want to discover lesser-known spots or go on day tours, think about booking your East Prairie vacation for longer.
How to find the best East Prairie package deals?
Use Expedia's filter tool to find some of the best East Prairie package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your break for midweek, or search for East Prairie package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to book your vacation package well in advance.
Is it cheaper to book an East Prairie vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll usually score a better deal than booking each component separately. And you'll still enjoy the flexibility to create a personalized East Prairie vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to East Prairie?
Score incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment East Prairie trip.
How to plan a trip to East Prairie?

  1. Choose your travel dates: The things you'd like to do in East Prairie and your preferred season can help you decide when to travel.
  2. Set your budget: Factor in expenses such as food, flights and transportation when calculating how much to set aside for your trip to East Prairie. Then, choose a hotel that fits your budget, whether that's a low-cost stay or a more luxurious getaway.
  3. Decide how long to go away for: Now that you know more about East Prairie, you can figure out the right length of your vacation. Pull together a rough itinerary and allocate enough time for all the things you want to do.
  4. Combine your airfare and accommodations: After you've nailed down your dates and duration, book the perfect East Prairie vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.