Title: Book The Best Hotels in Charleston, MO for 2025 from CA $85 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Charleston](https://expedia.ca/Charleston-Vacation-Rentals.d7182.Travel-Guide-VacationRentals)[Charleston Car Rentals](https://expedia.ca/Car-Rentals-In-Charleston.d7182.Car-Rental-Guide)[Charleston Vacation Packages](https://expedia.ca/Charleston.d7182.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Charleston, MO from CA $85 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Charleston Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2025-10-30&d1=2025-10-30&endDate=2025-11-01&d2=2025-11-01&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2025-10-30&d1=2025-10-30&endDate=2025-11-01&d2=2025-11-01&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2025-10-30&d1=2025-10-30&endDate=2025-11-01&d2=2025-11-01&amenities=POOL) ## Check prices for these dates Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=7182&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 89 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO Charleston 6.6/10 (597) "Tracey Allen checked me in. She was great!" CA $78 CA $86 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/fa992d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Charleston - Sikeston Charleston 6.8/10 (403) "I consistently choose to stay there due to positive past encounters." CA $92 CA $102 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/e769dedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/2b61a8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston Charleston 6.8/10 (102) "Comfortable bed, easy access to room" CA $93 CA $103 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1009) "Clean and comfortable " CA $88 CA $101 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (409) "Nice property and friendly staff." CA $149 CA $168 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8df39481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1013) "Wonderful place to stay" CA $105 CA $121 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1010) "Very convenient and great breakfast " CA $118 CA $135 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (432) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." CA $134 CA $151 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/3727e01c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/2dc19e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/a63c84b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (693) "The rooms are clean, staff very helpful. Could offer more variety for breakfast" CA $74 CA $85 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1007) "Very nice and quiet " CA $126 CA $145 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (557) "I enjoyed our stay" CA $83 CA $95 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1009) "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " CA $98 CA $111 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1017) "Great place" CA $126 CA $143 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1009) "Staff was very friendly and helpful would stay again " CA $98 CA $111 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1005) "Excellent place. Really friendly staff" CA $126 CA $143 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/af525dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/b77bd903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/a915fb4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (272) "The Jacuzzi was the Best!!! 👏" CA $124 CA $142 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1004) "It was right off the interstate with lots of restaurant options " CA $133 CA $151 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (455) "The Staff was friendly The restaurant was good" CA $176 CA $199 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.2/10 Wonderful (27) "Very clean and comfortable room. " CA $142 CA $161 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/4c2e6495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (756) "The property staff were lovely and the hotel was clean and renovated!" CA $149 CA $168 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=7182&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Hotels.d7182.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Hotels.d7182.Travel-Guide-Hotels) ## More cheap stays in Charleston ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO CA $156 CA $177 total Oct 26 - Oct 27 includes taxes & fees 9.2/10 Wonderful! (432 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO CA $98 CA $111 total Oct 19 - Oct 20 includes taxes & fees 8.8/10 Excellent! (1,008 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO CA $98 CA $111 total Oct 19 - Oct 20 includes taxes & fees 9/10 Wonderful! (1,008 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr, Sikeston, MO CA $88 CA $101 total Nov 2 - Nov 3 includes taxes & fees 7.2/10 Good! (1,004 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Sikeston 120 S Interstate Drive, Sikeston, MO CA $118 CA $135 total Oct 26 - Oct 27 includes taxes & fees 8.2/10 Very Good! (1,006 reviews) [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive, Sikeston, MO CA $149 CA $168 total Oct 26 - Oct 27 includes taxes & fees 8.8/10 Excellent! (404 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Hotels in Charleston with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_w.jpg) 3 Star Hotels 6 properties [](https://expedia.ca/3Star-Charleston-Hotels.s30-0-d7182.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_w.jpg) 2 Star Hotels 27 properties [](https://expedia.ca/2Star-Charleston-Hotels.s20-0-d7182.Travel-Guide-Filter-Hotels) ## Recent reviews of Charleston hotels ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 5/5 Excellent "Room was a bit on the small side, but comfortable." A verified traveller stayed at Pear Tree Inn Cape Girardeau Near the Medical Center Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 5/5 Excellent "Great staff " A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 5/5 Excellent "Very clean room as were all the facilities I used...Staff very friendly & helpful. " A verified traveller stayed at Pear Tree Inn Sikeston Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 5/5 Excellent "Very tasty buffet-style food every morning and evening, the suites were large & clean. All of the staff members were friendly & helpful: From the people at the front desk, to the folks preparing the food, to the housekeeping staff keeping the rooms and public areas all nice & tidy. 5 Stars!" A verified traveller stayed at Drury Inn & Suites Cape Girardeau Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 5/5 Excellent "Clean room. " A verified traveller stayed at Courtyard by Marriott Cape Girardeau Downtown Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 5/5 Excellent "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " A verified traveller from Foley stayed at Pear Tree Inn Cape Girardeau West Posted 7 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Best Western Plus Sikeston](//images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 5/5 Excellent "Room was clean and relaxing." A verified traveller from Spring stayed at Best Western Plus Sikeston Posted 7 days ago [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 5/5 Excellent "One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe " A verified traveller stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 5/5 Excellent "Kayla at the front desk was very helpful and accommodating when I first arrived. The room was very generous in space, clean and comfortable. A very quiet place to spend a night after 12 hours on the saddle. " A verified traveller stayed at Days Inn and Suites by Wyndham Sikeston Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ## Frequently asked questions ### What are the best budget hotels in Charleston? > [Quality Inn Charleston - Sikeston](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) is a fantastic budget-friendly option that provides families with a comfortable and convenient stay. Guests appreciate the complimentary breakfast, which includes a buffet spread great for fueling up before a day of adventures. The hotel also offers free WiFi, ensuring that you can stay connected throughout your visit. Families traveling with pets will find it particularly accommodating, as pets are permitted, and children can enjoy their stay for free. > > > > [Eagle Inn Charleston](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) is another excellent choice for budget-conscious travellers. This hotel not only provides free self-parking and high-speed internet but also features a health club for those who want to maintain their fitness routine. Additionally, the availability of rollaway extra beds at no additional cost makes it a great option for families needing a bit more space. View all [budget hotels in Charleston](https://www.expedia.ca/Charleston-Hotels-Cheap-Hotels.0-0-d7182-tCheapHotels.Travel-Guide-Filter-Hotels). ### When is the best time to go to Charleston? > The most popular time to visit Charleston is April, when the city's vibrant gardens are in full bloom, and the weather is pleasantly warm, with average temperatures ranging from 16 to 24°C. This makes it an ideal season for leisurely strolls along historic streets or relaxing in one of the many beautiful parks. > > > > During the peak season, from March to May, Charleston experiences a delightful surge in tourist activity. The pleasant climate and stunning scenery create a superb backdrop for outdoor adventures, including exploring the picturesque waterfront or taking a scenic carriage ride through the historic district. Many visitors find this time particularly enchanting, as the city hosts various festivals and events that showcase its rich culture and history. > > > > For couples looking to enjoy a romantic getaway, April offers a fantastic opportunity to indulge in outdoor dining experiences. Many restaurants feature charming patio seating where you can savour the local cuisine, perhaps enjoying fresh seafood or traditional Lowcountry dishes while taking in the beautiful surroundings. > > > > If your travel preferences lean towards a more budget-friendly approach, consider visiting in September. This month often sees reduced accommodation rates and fewer crowds, allowing you to explore the city's attractions at a more leisurely pace. The weather remains warm, making it comfortable for outdoor activities and sightseeing. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Charleston hotel for you. ### How can I save on a Charleston hotel booking with Expedia? > Before booking your Charleston hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Charleston hotel? > Prices for hotels in Charleston often vary, but you can find a great deal from CA $85 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Advance Hotels](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Benton](https://www.expedia.ca/Benton-Hotels-Cheap-Hotels.0-0-d553248634983369680-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Benton](https://www.expedia.ca/Benton-Hotels-Luxury-Hotel.0-0-d553248634983369680-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Benton Hotels](https://www.expedia.ca/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bernie Hotels](https://www.expedia.ca/Bernie-Hotels.d3000349284.Travel-Guide-Hotels) - 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