
Find hotels in Charleston, MO from CA $85
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Charleston
Pet friendly
Family friendly
Check prices for these dates
Our top choices for Charleston hotels

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (410 reviews)
The price is CA $121
CA $134 total
includes taxes & fees
Apr 21 - Apr 22

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (629 reviews)
The price is CA $88
CA $97 total
includes taxes & fees
Apr 12 - Apr 13

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
The price is CA $77
CA $85 total
includes taxes & fees
May 2 - May 3

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,009 reviews)
The price is CA $153
CA $176 total
includes taxes & fees
Apr 9 - Apr 10

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (172 reviews)
The price is CA $129
CA $145 total
includes taxes & fees
Apr 26 - Apr 27

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,000 reviews)
The price is CA $106
CA $121 total
includes taxes & fees
Apr 19 - Apr 20

La Center Motel
La Center MotelLa Center
7.6 out of 10, Good, (19 reviews)
The price is CA $75
CA $88 total
includes taxes & fees
Apr 8 - Apr 9

Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
The price is CA $168
CA $403 total
includes taxes & fees
Apr 14 - Apr 15

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (761 reviews)
The price is CA $91
CA $104 total
includes taxes & fees
Apr 8 - Apr 9

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,011 reviews)
The price is CA $139
CA $157 total
includes taxes & fees
Apr 19 - Apr 20

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,011 reviews)
The price is CA $100
CA $113 total
includes taxes & fees
Apr 12 - Apr 13

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (528 reviews)
The price is CA $143
CA $162 total
includes taxes & fees
Apr 12 - Apr 13

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (284 reviews)
The price is CA $104
CA $116 total
includes taxes & fees
Apr 19 - Apr 20

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (543 reviews)
The price is CA $169
CA $191 total
includes taxes & fees
Apr 8 - Apr 9

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (68 reviews)
The price is CA $153
CA $173 total
includes taxes & fees
Apr 19 - Apr 20

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (455 reviews)
The price is CA $146
CA $165 total
includes taxes & fees
Apr 26 - Apr 27

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
The price is CA $131
CA $148 total
includes taxes & fees
May 3 - May 4

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,003 reviews)
The price is CA $95
CA $108 total
includes taxes & fees
Apr 12 - Apr 13

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
The price is CA $192
CA $217 total
includes taxes & fees
Apr 20 - Apr 21

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is CA $164
CA $186 total
includes taxes & fees
May 7 - May 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Charleston
Quaint Charleston is calling! Discover its opera, entertainment, theater, and more.

Top Charleston Hotel Reviews
Recent Reviews in Charleston

Courtyard by Marriott Cape Girardeau Downtown
10/10 Excellent
More cheap stays in Charleston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
The price is CA $91 per night from Apr 8 to Apr 9
CA $91
CA $104 total
Apr 8 - Apr 9
includes taxes & fees
8.4/10 Very Good! (761 reviews)
Hotels in Charleston with star rating

3 Star Hotels
6 properties

2 Star Hotels
27 properties
Frequently asked questions
Explore a world of travel with Expedia
- Advance Hotels
- Apartments in Baker
- Apartments in Bell City
- Cheap Hotels in Benton
- Luxury Hotels in Benton
- Benton Hotels
- Bernie Hotels
- Cheap Hotels in Bertrand
- Hotels with a Pool in Bertrand
- Bertrand Hotels
- Motels in Bertrand
- Blodgett Hotels
- Bloomfield Hotels
- Apartments in Canalou
- Canalou Hotels
- Casino Hotels in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Hotels with a Pool in Cape Girardeau
- Hotels with Bar in Cape Girardeau
- Hotels with Free Airport Shuttle in Cape Girardeau
- Pet-Friendly Hotels in Cape Girardeau
- Spa Hotels in Cape Girardeau
- Cape Girardeau Hotels
- Inns in Cape Girardeau
- Rv Parks in Cape Girardeau
- Hotels near Cape Rock Park
- Catron Hotels
- Rv Parks in Chaffee
- Cabin Rentals in Commerce
- Mississippi County Hotels
- Dexter Hotels
- Hotels near eDen Spa & Salon
- East Prairie Hotels
- Essex Hotels
- Howardville Hotels
- Hotels near Isle Casino Cape Girardeau
- Jackson Hotels
- B&B in Kelso
- Marston Hotels
- Matthews Hotels
- Lodges in Matthews
- Hotels with smoking rooms in Miner
- Luxury Hotels in Miner
- Miner Hotels
- Lodges in Miner
- Apartments in Morehouse
- Morehouse Hotels
- Cheap Hotels in New Madrid
- Hotels with a Pool in New Madrid
- Luxury Hotels in New Madrid
- New Madrid Hotels
- B&B in Oran
- Hotels with a Pool in Oran
- Luxury Hotels in Oran
- Oran Hotels
- Inns in Oran
- Portageville Hotels
- Risco Hotels
- Cheap Hotels in Scott City
- Scott City Hotels
- Apartments in Sikeston
- Cheap Hotels in Sikeston
- Hotels with Kitchenettes in Sikeston
- Pet-Friendly Hotels in Sikeston
- Sikeston Hotels
- Hotels near Southeast Missouri State University
- Wilson City Hotels
- Flights to Cape Girardeau
- Flights from East Prairie
- Flights from Commerce
- Flights from Chaffee
- Flights from Scott City
- Flights from Cape Girardeau
- Flights from Accra (ACC) to Cape Girardeau (CGI)
- Flights from Bloomington (BMI) to Cape Girardeau (CGI)
- Flights from Buffalo (BUF) to Cape Girardeau (CGI)
- Flights from Colombo (CMB) to Cape Girardeau (CGI)
- Flights from Dhaka (DAC) to Cape Girardeau (CGI)
- Flights from Detroit (DTW) to Sikeston (SIK)
- Flights from Grand Island (GRI) to Cape Girardeau (CGI)
- Flights from New York (JFK) to Cape Girardeau (CGI)
- Flights from Las Vegas (LAS) to Cape Girardeau (CGI)
- Flights from Ocala (OCF) to Cape Girardeau (CGI)
- Flights from Pierre (PIR) to Cape Girardeau (CGI)
- Flights from St. Louis (STL) to Cape Girardeau (CGI)
- Flights from Edmonton (YEG) to Cape Girardeau (CGI)
- Flights from Toronto (YTO) to Cape Girardeau (CGI)
- Flights from Montreal (YUL) to Cape Girardeau (CGI)
- Flights from Vancouver (YVR) to Cape Girardeau (CGI)
- Flights from Winnipeg (YWG) to Cape Girardeau (CGI)
- Flights from Calgary (YYC) to Cape Girardeau (CGI)
- Flights from Toronto (YYZ) to Cape Girardeau (CGI)









































































