A sunset over a calm lake with tall trees reflected in the water.

Charleston Vacation Rentals

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Our top choices for Charleston vacation rentals

1. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (44 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is CA $159
CA $186 total
includes taxes & fees
Nov 9 - Nov 10
Cozy cabins on beautiful Horseshoe Lake

2. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (32 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is CA $159
CA $186 total
includes taxes & fees
Nov 9 - Nov 10
The Rested Duck Mallard Room

3. Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (40 reviews)
"Great place in a beautiful location. "
United States
George B.
The price is CA $198
CA $290 total
includes taxes & fees
Nov 15 - Nov 16
Peaceful secluded cabin located near Horseshoe Lake

4. Perfect Couples Retreat - firepit

Perfect Couples Retreat - firepit
Carlisle County
10.0 out of 10, Exceptional, (1 review)
"This is such a quaint unique property. The host was very responsive and communicative. Highly recommend"
United States
Russell
The price is CA $173
CA $253 total
includes taxes & fees
Nov 9 - Nov 10
Perfect Couples Retreat - firepit

5. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is CA $211
CA $410 total
includes taxes & fees
Nov 9 - Nov 10
Quiet Country Stay: Modern Home Near Paducah

6. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is CA $114
CA $141 total
includes taxes & fees
Nov 9 - Nov 10
Little Blue Cottage on Spanish

7. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
10.0 out of 10, Exceptional, (4 reviews)
"Host was great. "
United States
Sheila C.
The price is CA $154
CA $401 total
includes taxes & fees
Nov 9 - Nov 10
Quiet Country Stay: Modern Home Near Paducah

8. Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (26 reviews)
"Location was great. Beds were so comfortable, place was so clean and nice. Very cute place to stay. Would stay here again!"
United States
Deannena H.
The price is CA $155
CA $279 total
includes taxes & fees
Nov 22 - Nov 23
Charming Home just minutes from Interstate and Mall

9. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (6 reviews)
"Great place to stay with our dogs while in town visiting family. We were kept busy by the activities available in the cabin and enjoyed the peace outside. We were tempted to ride the trails, which looked nice, but only didn’t because we opted for mud. High likelihood we will be back. Our dogs were happy and so were we."
United States
Alexia G.
The price is CA $254
CA $358 total
includes taxes & fees
Nov 22 - Nov 23
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

10. The Roost | Hot Tub, Ponds & Farm Views

The Roost | Hot Tub, Ponds & Farm Views
Carlisle County
The price is CA $202
CA $286 total
includes taxes & fees
Nov 11 - Nov 12
The Roost | Hot Tub, Ponds & Farm Views

11. Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (10 reviews)
"The home was spotless, very comfortable and a great location for what we needed."
United States
Sherrie S.
The price is CA $141
CA $218 total
includes taxes & fees
Nov 9 - Nov 10
Vacation rental attached to our house out in the country.

12. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is CA $151
CA $250 total
includes taxes & fees
Dec 1 - Dec 2
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

13. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is CA $283
CA $478 total
includes taxes & fees
Nov 9 - Nov 10
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

14. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is CA $253
CA $427 total
includes taxes & fees
Nov 9 - Nov 10
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

15. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is CA $507
CA $782 total
includes taxes & fees
Nov 9 - Nov 10
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Charleston Hotel Reviews

Find out more about Charleston

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Charleston. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Charleston?

Yes, we have vacation rentals close to the most popular sights in Charleston, or you can go with a secluded option if you want a relaxing place to stay. Our travelers say Charleston has a good selection of restaurants. Make sure you have time to check out the entertainment choices and theaters during your trip.

What are some of the best vacation rentals that Charleston has to offer?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: Visitors like this Charleston vacation home rental. It is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in Charleston?

Mississippi River and Ohio River are a couple of lovely local spots to get outside and enjoy nature. Ballard Wildlife Management Area and Columbus-Belmont State Park are a couple of places you'll find in the larger area.

What are vacation rentals like in Charleston?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Charleston. Vacation rentals feature extras like WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for family trips.