Title: Book The Best Hotels in Advance, MO for 2025 from CA $87 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Advance](https://expedia.ca/Advance-Vacation-Rentals.d553248634983475122.Travel-Guide-VacationRentals)[Advance Car Rentals](https://expedia.ca/Car-Rentals-In-Advance.d553248634983475122.Car-Rental-Guide)[Advance Vacation Packages](https://expedia.ca/Advance.d553248634983475122.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Advance, MO from CA $87 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Advance Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Advance%2C+Missouri%2C+United+States+of+America®ionId=553248634983475122&latLong=37.104496%2C-89.910652&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=PETS) ## Check prices for these dates Tonight [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=553248634983475122&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=553248634983475122&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983475122&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248634983475122&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 109 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1019) "Very nice hotel and nice staff " CA $125 CA $141 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1016) "Was a clean room, nice staff, good parking " CA $125 CA $132 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1001) "Excellent place. Really friendly staff" CA $125 CA $141 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/fc288d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/5f50a8a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel Marble Hill 9.6/10 Exceptional (78) "Quiet small town vibe, great food and service! Definitely recommend " CA $146 CA $159 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (451) "The Staff was friendly The restaurant was good" CA $174 CA $197 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (65) "Great overall stay" CA $141 CA $160 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (129) "The hotel was very clean and updated and the staff was super friendly and very informative!" CA $129 CA $146 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1011) "My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there." CA $97 CA $110 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1009) "Staff was friendly, room was clean, good location, good rate." CA $97 CA $110 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (624) "Excellent place to stay. Breakfast was good and staff was friendly. " CA $117 CA $127 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1001) "It was right off the interstate with lots of restaurant options " CA $132 CA $149 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/cfaba55a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/4c2e6495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (747) "Would prefer onsite restaurant and bar" CA $152 CA $172 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.4/10 Exceptional (25) "Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good" CA $140 CA $159 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (398) "Nice property and friendly staff." CA $148 CA $167 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (431) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." CA $146 CA $165 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (734) "Great area, fast check in, quiet, very spacious" CA $124 CA $134 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/e322869e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/cc0ef67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG Cape Girardeau 8.0/10 Very good (848) "Great staff and convenient location " CA $103 CA $124 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (414) "It was easy and quiet and an easy check in " CA $80 CA $87 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (643) "nice stay" CA $80 CA $90 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a102ce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/dbe031d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/eaa414ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn Cape Girardeau 10/10 Exceptional (16) "We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! " CA $200 CA $226 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=553248634983475122&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FAdvance-Hotels.d553248634983475122.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FAdvance-Hotels.d553248634983475122.Travel-Guide-Hotels) ## More cheap stays in Advance ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO CA $171 CA $193 total Sep 28 - Sep 29 includes taxes & fees 9.2/10 Wonderful! (420 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO CA $97 CA $110 total Sep 28 - Sep 29 includes taxes & fees 8.8/10 Excellent! (1,003 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO CA $97 CA $110 total Sep 28 - Sep 29 includes taxes & fees 9/10 Wonderful! (1,007 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive, Sikeston, MO CA $148 CA $167 total Oct 5 - Oct 6 includes taxes & fees 8.8/10 Excellent! (397 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street, Cape Girardeau, MO CA $132 CA $149 total Oct 19 - Oct 20 includes taxes & fees 9.4/10 Exceptional! (1,008 reviews) [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Cape Girardeau 433 CAPE WEST CROSSINGS, Cape Girardeau, MO CA $129 CA $146 total Oct 2 - Oct 3 includes taxes & fees 9.2/10 Wonderful! (128 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ## Hotels in Advance with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_w.jpg) 3 Star Hotels 9 properties [](https://expedia.ca/3Star-Advance-Hotels.s30-0-d553248634983475122.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_w.jpg) 2 Star Hotels 24 properties [](https://expedia.ca/2Star-Advance-Hotels.s20-0-d553248634983475122.Travel-Guide-Filter-Hotels) ## Recent reviews of Advance hotels ![Fairfield Inn & Suites by Marriott Sikeston](//images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 5/5 Excellent "The stars tell it all😉" A verified traveller stayed at Fairfield Inn & Suites by Marriott Sikeston Posted 3 days ago [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 5/5 Excellent Definitely recommend "Very clean, sincerely friendly staff and very helpful. Pillows and bed comfy. Great location. " A verified traveller stayed at Pear Tree Inn Cape Girardeau West Posted 3 days ago [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 5/5 Excellent "Brand new hotel and it’s not even shown on Google maps. Great condition and service!" A verified traveller stayed at Tru By Hilton Cape Girardeau Posted 4 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 5/5 Excellent "My husband and I love this hotel. We stay here every single time we are in the area. While it’s a little pricier than a few other options it is definitely worth it for us. The hotel is beautiful and the staff is always very accommodating. Emily and the rest of the staff are so sweet and helpful. We will be back soon and can’t wait! " A verified traveller stayed at Courtyard by Marriott Cape Girardeau Downtown Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](//images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 5/5 Excellent "Good" A verified traveller stayed at Hampton Inn Cape Girardeau I 55 East Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 5/5 Excellent "It was right off the interstate with lots of restaurant options " A verified traveller stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 5/5 Excellent "Helpful staff." A verified traveller stayed at The Riverview Posted 6 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent Great hotel at a great location for a great price. "Drury Inn & Suites in Jackson Mo is always a great place to stay. We stay here every year for a local volleyball tournament and they always take care of us." A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 7 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Everything was good i would recommend this place to people" A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 7 days ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Advance hotel for you. ### How can I save on a Advance hotel booking with Expedia? > Members always get our best prices. Find our best Advance hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Advance hotel? > Prices for hotels in Advance often vary, but you can find a great deal from CA $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Benton](https://www.expedia.ca/Benton-Hotels-Cheap-Hotels.0-0-d553248634983369680-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Benton](https://www.expedia.ca/Benton-Hotels-Luxury-Hotel.0-0-d553248634983369680-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Benton Hotels](https://www.expedia.ca/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bernie Hotels](https://www.expedia.ca/Bernie-Hotels.d3000349284.Travel-Guide-Hotels) - [Bertrand Hotels](https://www.expedia.ca/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels](https://www.expedia.ca/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Apartments in Bloomfield](https://www.expedia.ca/Bloomfield-Apartments.d6351829-aaApartments.Travel-Guide-Accommodation) - [Bloomfield Hotels](https://www.expedia.ca/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Resorts in Bloomfield](https://www.expedia.ca/Bloomfield-Resort-Hotels.d6351829-aaResortHotels.Travel-Guide-Accommodation) - [Canalou Hotels](https://www.expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Rv Parks in Cape Girardeau County](https://www.expedia.ca/Cape-Girardeau-County-RV-Parks.d553248635976430467-aaRVParks.Travel-Guide-Accommodation) - [Cape Girardeau Hotels](https://www.expedia.ca/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Hotels near Cape Rock Park](https://www.expedia.ca/Cape-Rock-Park-Hotels.0-l553248621532655781-0.Travel-Guide-Filter-Hotels) - [Rv Parks in Chaffee](https://www.expedia.ca/Chaffee-RV-Parks.d553248634983269107-aaRVParks.Travel-Guide-Accommodation) - [Charleston Hotels](https://www.expedia.ca/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Wayne County Hotels](https://www.expedia.ca/Destinations-In-Wayne-County.d553248635976433836.Hotel-Destinations) - [Apartments in Dexter](https://www.expedia.ca/Dexter-Apartments.d55097-aaApartments.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Dexter](https://www.expedia.ca/Dexter-Hotels-Beach-Hotel.0-0-d55097-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Dexter](https://www.expedia.ca/Dexter-Hotels-Cheap-Hotels.0-0-d55097-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Dexter](https://www.expedia.ca/Dexter-Hotels-Hotel-With-Pool.0-0-d55097-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Dexter](https://www.expedia.ca/Dexter-Hotels-Hotels-With-Free-Breakfast.0-0-d55097-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Dexter](https://www.expedia.ca/Dexter-Hotels-Pet-Friendly-Hotel.0-0-d55097-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Dexter Hotels](https://www.expedia.ca/Dexter-Hotels.d55097.Travel-Guide-Hotels) - [Motels in Dexter](https://www.expedia.ca/Dexter-Motels.d55097-aaMotels.Travel-Guide-Accommodation) - [Resorts in Dexter](https://www.expedia.ca/Dexter-Resort-Hotels.d55097-aaResortHotels.Travel-Guide-Accommodation) - [Dudley Hotels](https://www.expedia.ca/Dudley-Hotels.d553248634983299889.Travel-Guide-Hotels) - [Hotels near eDen Spa & Salon](https://www.expedia.ca/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels) - [Essex Hotels](https://www.expedia.ca/Essex-Hotels.d553248634983169000.Travel-Guide-Hotels) - [Fruitland Hotels](https://www.expedia.ca/Fruitland-Hotels.d553248635975866670.Travel-Guide-Hotels) - [Glen Allen Hotels](https://www.expedia.ca/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Vacation Homes in Glen Allen](https://www.expedia.ca/Glen-Allen-Private-Vacation-Homes.d553248634983455025-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Greenville Hotels](https://www.expedia.ca/Greenville-Hotels.d553248634983564794.Travel-Guide-Hotels) - [Hotels near Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels) - [B&B in Jackson](https://www.expedia.ca/Jackson-Bed-And-Breakfast.d55765-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Free Breakfast in Jackson](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Free-Breakfast.0-0-d55765-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Jackson](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Hot-Tubs.0-0-d55765-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Jackson](https://www.expedia.ca/Jackson-Hotels-Hotels-With-Kitchenettes.0-0-d55765-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Jackson](https://www.expedia.ca/Jackson-Hotels-Pet-Friendly-Hotel.0-0-d55765-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Jackson Hotels](https://www.expedia.ca/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Palaces in Jackson](https://www.expedia.ca/Jackson-Palaces.d55765-aaPalaces.Travel-Guide-Accommodation) - [B&B in Kelso](https://www.expedia.ca/Kelso-Bed-And-Breakfast.d553248634983171130-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Malden Regional](https://www.expedia.ca/Malden-Regional-Airport-Hotels.0-aMAW-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Marble Hill](https://www.expedia.ca/Marble-Hill-Hotels-Cheap-Hotels.0-0-d3000445212-tCheapHotels.Travel-Guide-Filter-Hotels) - [Marble Hill Hotels](https://www.expedia.ca/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Matthews Hotels](https://www.expedia.ca/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Luxury Hotels in Miner](https://www.expedia.ca/Miner-Hotels-Luxury-Hotel.0-0-d553248634983441802-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Miner Hotels](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Apartments in Morehouse](https://www.expedia.ca/Morehouse-Apartments.d553248634983462037-aaApartments.Travel-Guide-Accommodation) - [Morehouse Hotels](https://www.expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [B&B in Oran](https://www.expedia.ca/Oran-Bed-And-Breakfast.d3000445386-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with a Pool in Oran](https://www.expedia.ca/Oran-Hotels-Hotel-With-Pool.0-0-d3000445386-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Oran](https://www.expedia.ca/Oran-Hotels-Luxury-Hotel.0-0-d3000445386-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oran Hotels](https://www.expedia.ca/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Inns in Oran](https://www.expedia.ca/Oran-Inns.d3000445386-aaInns.Travel-Guide-Accommodation) - [Puxico Hotels](https://www.expedia.ca/Puxico-Hotels.d553248634983343452.Travel-Guide-Hotels) - [Cheap Hotels in Scott City](https://www.expedia.ca/Scott-City-Hotels-Cheap-Hotels.0-0-d553248634983544376-tCheapHotels.Travel-Guide-Filter-Hotels) - [Scott City Hotels](https://www.expedia.ca/Scott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) - [Apartments in Sikeston](https://www.expedia.ca/Sikeston-Apartments.d6058766-aaApartments.Travel-Guide-Accommodation) - [Cheap Hotels in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Cheap-Hotels.0-0-d6058766-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Hotels-With-Kitchenettes.0-0-d6058766-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Sikeston](https://www.expedia.ca/Sikeston-Hotels-Pet-Friendly-Hotel.0-0-d6058766-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Sikeston Hotels](https://www.expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Southeast Missouri Hotels](https://www.expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Hotels near Southeast Missouri State University](https://www.expedia.ca/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Wappapello](https://www.expedia.ca/Wappapello-Hotels-Cheap-Hotels.0-0-d183505-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Wappapello](https://www.expedia.ca/Wappapello-Hotels-Luxury-Hotel.0-0-d183505-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Flights to Dexter](https://www.expedia.ca/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights) - [Flights to Jackson](https://www.expedia.ca/Cheap-Flights-To-Jackson.d55765.Travel-Guide-Flights) - [Flights from Chaffee](https://www.expedia.ca/lp/flights/553248634983269107/flights-from-chaffee) - [Flights from Scott City](https://www.expedia.ca/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Accra (ACC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/acc/cgi/accra-to-cape-girardeau) - [Flights from Bloomington (BMI) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/bmi/cgi/bloomington-to-cape-girardeau) - [Flights from Buffalo (BUF) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/buf/cgi/buffalo-to-cape-girardeau) - [Flights from Colombo (CMB) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/cmb/cgi/colombo-to-cape-girardeau) - [Flights from Dhaka (DAC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/dac/cgi/dhaka-to-cape-girardeau) - [Flights from Detroit (DTW) to Sikeston (SIK)](https://www.expedia.ca/lp/flights/dtw/sik/detroit-to-sikeston) - [Flights from Grand Island (GRI) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/gri/cgi/grand-island-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from Las Vegas (LAS) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/las/cgi/las-vegas-to-cape-girardeau) - [Flights from Ocala (OCF) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/ocf/cgi/ocala-to-cape-girardeau) - [Flights from Pierre (PIR) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/pir/cgi/pierre-to-cape-girardeau) - [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Edmonton (YEG) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yeg/cgi/edmonton-to-cape-girardeau) - [Flights from Toronto (YTO) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yto/cgi/toronto-to-cape-girardeau) - [Flights from Montreal (YUL) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yul/cgi/montreal-to-cape-girardeau) - [Flights from Vancouver (YVR) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yvr/cgi/vancouver-to-cape-girardeau) - [Flights from Winnipeg (YWG) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/ywg/cgi/winnipeg-to-cape-girardeau) - [Flights from Calgary (YYC) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yyc/cgi/calgary-to-cape-girardeau) - [Flights from Toronto (YYZ) to Cape Girardeau (CGI)](https://www.expedia.ca/lp/flights/yyz/cgi/toronto-to-cape-girardeau) - [Wappapello Vacations](https://www.expedia.ca/Wappapello.d183505.Destination-Travel-Guides) - [Avis Rental Cars in Sikeston](https://www.expedia.ca/Avis-Car-Rentals-In-Sikeston.d6058766-c41.Car-Rental-Guide-Suppliers) - [Rental cars Cape Girardeau Municipal airport](https://www.expedia.ca/Car-Rentals-In-Cape-Girardeau-Municipal.d6026978.Car-Rental-Guide) - [Car rental Sikeston](https://www.expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide) - [Car rentals near Cape Girardeau County](https://www.expedia.ca/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Rental-Destinations) - [Hertz Rental Cars in Marble Hill](https://www.expedia.ca/Hertz-Car-Rentals-In-Marble-Hill.d3000445212-c40.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Sikeston](https://www.expedia.ca/Hertz-Car-Rentals-In-Sikeston.d6058766-c40.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Sikeston](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Sikeston.d6058766-c42.Car-Rental-Guide-Suppliers) - [Marble Hill Vacation Rentals](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals) - [Book Hotels in Advance on Expedia.com](https://www.expedia.com/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)