Book The Best Hotels in St Mary, MO for 2026 from CA $85 - Fully Refundable Options

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Our top choices for St Mary hotels

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A gym with treadmills, a weight machine, and exercise balls.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

1. Baymont by Wyndham Chester IL

Chester

Keng

CA $129

CA $144 total

includes taxes & fees

Sep 15 - Sep 16

A row of single-story houses with attached garages, a paved driveway, and a clear sky.

A modern living room with a flat-screen TV, a desk with a computer, two armchairs, a coffee table, and large windows with a view.

A hotel dining area with tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

A reception desk with a digital map of the USA, a wooden reception area, and a sign for 'MICROHOTEL BY JYNDHAMI'.

2. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

CA $125

CA $147 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

3. Holiday Inn Express & Suites Perryville by IHG

Perryville

David

CA $135

CA $154 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

4. Super 8 by Wyndham Perryville

Perryville

Elizabeth

CA $97

CA $111 total

includes taxes & fees

Sep 13 - Sep 14

A compact kitchen with black cabinets, a black refrigerator, a microwave, and a sink.

A parking lot with a sign for Triangle Inn.

A building with a stone facade, a yellow door, a green chair, and a potted plant.

5. Triangle Inn Motel

Ste Genevieve

rocky

CA $75

CA $88 total

includes taxes & fees

Oct 1 - Oct 2

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

6. Perryville RV Resort

Perryville

Von

CA $92

CA $105 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

7. Days Inn by Wyndham Perryville

Perryville

Wanda

CA $99

CA $113 total

includes taxes & fees

Sep 15 - Sep 16

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

8. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

CA $94

CA $107 total

includes taxes & fees

Sep 13 - Sep 14

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

9. The Atrium - A Boutique Hotel

Perryville

Brian

CA $105

CA $221 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A Country Inn Motel sign, a parking lot, and a building with an American flag.

A hotel room with two beds, a television, a desk, and a window with curtains.

10. Red Bud Country Inn

Red Bud

Richard

CA $118

CA $131 total

includes taxes & fees

Sep 17 - Sep 18

A cabin with a large window, surrounded by trees.

A cabin with a cozy interior, a dining area, and a visible window.

11. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

Ronrecus

CA $140

CA $223 total

includes taxes & fees

Oct 1 - Oct 2

A large, two-story house with a wrap-around porch and a central tower.

A covered patio with a picnic table, surrounded by a brick pathway and greenery.

A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.

A four-poster canopy bed with a wooden headboard, a chandelier, and a radiator on the floor.

12. The Conner House B&B

Prairie du Rocher

James

CA $217

CA $240 total

includes taxes & fees

Sep 15 - Sep 16

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A hot tub area with a view of the parking lot through a glass door.

A large brick building with a central entrance flanked by columns, likely a hotel or office building.

13. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Joseph

CA $135

CA $150 total

includes taxes & fees

Sep 6 - Sep 7

A covered porch with a metal railing, a red carpet, and a green chair.

A bedroom with a floral bedspread, a wooden wardrobe, a white refrigerator, and a door with a sign.

A hotel room with a wooden TV stand, a door leading to a bathroom, and a hallway with a patterned ceiling.

A motel with multiple balconies, American flags, and outdoor seating.

14. K-River Motel & Campground

Baldwin

Joyce

CA $90

CA $100 total

includes taxes & fees

Sep 8 - Sep 9

A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.

A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.

A modern kitchen with granite countertops, wooden chairs, and a dining table. There are various food items and a sign indicating hot beverages.

An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.

15. Quality Inn Farmington

Farmington

Dave

CA $82

CA $94 total

includes taxes & fees

Sep 20 - Sep 21

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

A gym with cardio equipment, a bench press, and a squat rack.

A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.

16. Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

ILUNGA

CA $78

CA $85 total

includes taxes & fees

Sep 13 - Sep 14

A modern kitchen with a coffee machine, a refrigerator, and a microwave.

A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.

A laundry room with a front-loading washer and dryer, a door, and a light fixture.

A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

17. Super 8 by Wyndham Farmington

Farmington

John

CA $81

CA $89 total

includes taxes & fees

Sep 13 - Sep 14

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

18. Urban Lofts

Perryville

Grace

CA $279

CA $431 total

includes taxes & fees

Sep 28 - Sep 29

A modern bedroom with a large bed, a desk with a computer, a chair, and a window with a view of a lake.

A bathroom with a beige sink, a mirror, a towel rack, and a trash bin.

A grassy field with a small building, a fenced area, and a few vehicles.

19. Briarwood Inn of Sparta

Sparta

Steve

CA $124

CA $137 total

includes taxes & fees

Sep 3 - Sep 4

A hotel room with two beds, a nightstand with a lamp, a small window, and curtains.

A small, enclosed shower stall with a drain, a towel rack, and a shower control knob.

A small, single-story wooden building with a flat roof, a front door, and windows.

A room with a sofa, a fan, a door with a sign, and a window.

20. Sparta Motel Near St. Louis / Mississippi River IL

Sparta

Stacey

CA $97

CA $117 total

includes taxes & fees

Sep 15 - Sep 16

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Top St Mary Hotel Reviews

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Absolutely fabulous hotel!"

Madison Inn Lodge

10/10 Excellent

"Nice and clean friendly staff"

Crown Pointe Lodge, BW Signature Collection

10/10 Excellent

"One of the cleanest hotels I have ever stayed at. Located in a very quiet area."

Super 8 by Wyndham Farmington

8/10 Good

"Best Super 8 stay I’ve had. Helpful and happy staff. Very clean rooms with daily service (something other hotels don’t seem to offer on long stays anymore). Close dining and shopping options. Close to state parks and other state attractions. Vending machine and a fair breakfast for food options. The pool, although I didn’t use, looked very well maintained. Blackout curtains and a pristine shower. My very minor complaints is plug in options. A lot of hotels nowadays have headlamps next to the bed with an outlet now. So to charge your phone the light needs to be left on…not great when you’re trying to sleep. Breakfast could also have more options than bread (bagels, biscuits, and toast), apples, and cereal. Besides that this was an excellent stay."

Private Hot Tub + Fire Pit | 4BR/2Bth Ranch | 10 Min to Historic Ste. Genevieve by Timber Oaks Vacation Rentals

10/10 Excellent

"Loved the quiet location close to great roads for our motorcycle trip. Very clean, plenty of room, and the host was quick to respond to questions. Would definitely stay here again if we're back in the area."

Missouri Castle w/ Private Lake, Pool & 100 Acres!

10/10 Excellent

"Fantastic property with a great location! Secluded with plenty to stay entertained, will definitely book again in the future!"

Holiday Inn Express & Suites Farmington by IHG

10/10 Excellent

"Clean and well maintained as you would expect from this chain."

Microtel Inn & Suites by Wyndham Sainte Genevieve

8/10 Good

"The Breakfast items were a bit stale. Staff was not super helpful."

Silo Farm Haus- located in the heart of wine country!

10/10 Excellent

"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire stay was starting each morning on the porch swing, watching the sunrise while listening to the sounds of nature. It was such a calming and memorable experience.The house itself was immaculate and thoughtfully equipped with every amenity you could possibly need. It was clear that every detail had been considered to make guests feel comfortable and at home.We couldn’t have asked for a better getaway and would absolutely stay here again. Highly recommend the Silo House to anyone looking for a peaceful, beautiful retreat!"

More cheap stays in St Mary

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

CA $78

CA $85 total

Sep 13 - Sep 14

includes taxes & fees

Super 8 by Wyndham Farmington

930 Valley Creek Dr Farmington MO

CA $81

CA $89 total

Sep 13 - Sep 14

includes taxes & fees

8/10 Very good! (669 reviews)

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

CA $97

CA $111 total

Sep 13 - Sep 14

includes taxes & fees

Baymont by Wyndham Chester IL

2150 State Street Chester IL

CA $129

CA $144 total

Sep 15 - Sep 16

includes taxes & fees

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

CA $135

CA $154 total

Sep 6 - Sep 7

includes taxes & fees

9.2/10 Wonderful! (621 reviews)

Crown Pointe Lodge, BW Signature Collection

4245 Hunt Rd Farmington MO

CA $152

CA $166 total

Sep 13 - Sep 14

includes taxes & fees

9/10 Wonderful! (673 reviews)

Hotels in St Mary with star rating

Find out more about St Mary

Top reasons to visit St Mary

Outdoor Adventures: Enjoy a variety of outdoor activities in St. Mary, perfect for nature enthusiasts and adventure seekers.
Charming Historic District: Stroll through picturesque streets filled with friendly locals and explore the rich history of the area.
Live Music Events: Experience the vibrant entertainment scene with daily live music, enhancing your visit with local culture.
Family-Friendly Activities: Engage in numerous family-friendly excursions and recreational opportunities available in the area.
Diverse Accommodations: Choose from budget-friendly motels to comfortable hotels, catering to every traveler's needs.

Find great hotels in St Mary

Discover a variety of hotel accommodations in St. Mary, Missouri, tailored to suit every traveler's needs. From budget-friendly motels to comfortable 3.5-star hotels, you'll find the perfect place to unwind. Ideal for pet lovers and adventure seekers, St. Mary offers an array of amenities to enhance your stay. Explore the best hotels in St. Mary to ensure a memorable vacation experience in this charming destination.

Super 8 by Wyndham Perryville: Located 19.3km from St Mary, Super 8 by Wyndham Perryville offers a welcoming atmosphere for both business and pet travellers. This motel is designed with practicality in mind, featuring essential business amenities such as a Meeting Room and a Business Centre, making it an excellent choice for corporate guests. Pet owners will appreciate the pet-friendly policy, allowing pets on-site with some restrictions. With a focus on comfort and convenience, Super 8 provides a great base for exploring the area while accommodating your furry friends.
Holiday Inn Express & Suites Perryville by IHG: Situated 19.3km away from St Mary, Holiday Inn Express & Suites Perryville is a modern hotel tailored for business travellers. It boasts a comprehensive Business Centre and accessible Meeting Rooms, ensuring that your corporate needs are met seamlessly. Guests can enjoy a complimentary breakfast to kickstart their day, and the hotel’s contemporary design promotes a relaxing atmosphere after work. Ideal for those seeking a professional yet comfortable stay, this hotel is a solid choice for your Perryville visit.
Baymont by Wyndham Chester IL: Located 12.9km from St Mary, Baymont by Wyndham Chester IL caters to both business and pet travellers with its versatile amenities. The hotel features a 24-hour Business Centre, ensuring that guests can attend to work matters at any time, along with standard business facilities. With a pet-friendly policy that welcomes dogs, this hotel provides a homey feel for those travelling with pets. Guests can enjoy a comfortable stay while balancing work and leisure in a charming setting.

Where to stay in St Mary

St. Mary, Missouri, offers a delightful blend of outdoor adventures and romantic escapes. Stroll through the charming streets near historic St. Mary, where friendly locals welcome you. Enjoy family-friendly excursions, explore local sports stadiums, or simply bask in the area's rich history. Nearby attractions provide great options for your next getaway, all within walking distance, making it easy to soak up the vibrant atmosphere of this inviting city.

Ste Genevieve: Located a mere 14.5km from St Mary, Ste Genevieve is a charming city steeped in history and natural beauty. This destination is perfect for those seeking outdoor adventures, romantic getaways, or entertaining experiences. From recreational areas to campgrounds, there's plenty to engage visitors year-round. Noteworthy landmarks include a national state park, a serene lake, and an event conference venue, making it a great stop for both leisure and festivities.
Perryville: Situated 17.7km from St Mary, Perryville boasts a picturesque landscape that draws visitors seeking outdoor activities and stunning scenery. The city is particularly popular during the warmer months, peaking from June to August. Visitors can enjoy recreational areas and renowned golf courses, while the nearby lake and national state park provide additional opportunities for exploration. Perryville's blend of romance and natural charm makes it an ideal retreat for couples and nature enthusiasts alike.
Menard: Nestled within the area of St Mary, Menard is a quaint village that invites visitors to immerse themselves in its outdoor and scenic offerings. With a steady flow of tourists, especially from June to November, Menard is known for its recreational areas and proximity to natural attractions. Local highlights include a beautiful lake, a peaceful park, and intriguing caves, providing ample opportunities for exploration and relaxation in a tranquil setting.

Things to do in St Mary

St. Mary, Missouri, offers a delightful mix of outdoor activities and romantic settings perfect for a memorable vacation. You can explore the local recreational area, enjoy leisurely strolls in the recreation park, and indulge in some shopping at the shopping centre. Don't miss out on the daily live music events that add to the town's vibrant entertainment scene, making it an enjoyable destination for all visitors.

Recreation

Experience the thrill of ice skating at Chester Skating Rink, just 12.9km from St Mary, where you can enjoy sports and entertainment. For a relaxing day outdoors, visit Pickle Springs Natural Area, 32.2km away, offering serene trails and a chance to unwind in nature.

Adventure

The World Shooting and Recreational Complex, located 38.6km from St Mary, offers thrilling shooting ranges and outdoor activities. Experience archery, sporting clays, and various events that cater to all skill levels, making it an exciting destination for adventure enthusiasts and families alike.

Booking tips and Expedia advantages for St Mary

To save money during your visit to St. Mary, Missouri, take advantage of free attractions like the National Shrine of Our Lady of the Miraculous Medal and Elzie C. Segar Memorial Park. Opt for walking or cycling to explore the area affordably. Consider visiting during the cheaper months of January to February or November, and stay on a Wednesday for the best hotel rates. Use Expedia to find budget-friendly accommodations, and consider combining your hotel, flights, and activities for additional savings. Look for eco-certified hotels to support sustainable travel while keeping costs down.

The most and least expensive months on average to stay in a hotel: The cheapest months to stay in St Mary are January to February and November, where the prices are slightly lower. This is in comparison to April and July to August, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay in St Mary is Wednesday. The most expensive day to stay in St Mary is Saturday.
Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your choices based on your budget, desired location, and preferred type of accommodation. For instance, by selecting the "Eco-certified" option, you'll be able to view sustainable and environmentally friendly hotels that are currently available. To discover the most affordable rates and special offers, simply arrange the price filter from lowest to highest.
Consider bundling your trip: You can save some money by combining your St. Mary hotel reservation with your flights and activities through an Expedia package.

Find the best attractions in St Mary

St. Mary, Missouri is a charming destination perfect for outdoor enthusiasts, couples, and those seeking entertainment. Visitors can explore historic sites, engaging museums, and beautiful islands, all while enjoying a rich cultural experience. Don't miss the chance to discover the history of St. Mary, as it offers a delightful blend of family-friendly activities and scenic adventures. Whether you're in search of romance or outdoor fun, St. Mary has something for everyone.

Fort Kaskaskia: Located 9.7km from St Mary, this historic fort offers a glimpse into early American history. Enjoy the stunning views of the Mississippi River while exploring the remnants of this once-vital military post, where you can immerse yourself in the rich cultural heritage of the region.
Popeye Museum: Situated 11.3km away, this quirky museum celebrates the beloved cartoon character Popeye. Dive into the world of animated nostalgia, featuring memorabilia, artwork, and exhibits that showcase the cultural impact of this iconic sailor.
Pierre Menard Home: Also located 9.7km from St Mary, this historic house is a beautifully preserved example of early 19th-century architecture. Wander through its rooms to discover the life of Pierre Menard, the first lieutenant governor of Illinois, and learn about the area's rich history.

Best time to go to St Mary

Visitor numbers in St Mary is generally unchanged in popularity throughout the year. The best time to visit St Mary is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	32.9°F (0.5°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low
February	36.0°F (2.2°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low
March	46.9°F (8.3°C)	Light Rain	Mostly Sunny	Average	Average
April	56.1°F (13.4°C)	Light Rain	Mostly Sunny	Average	Slightly High
May	66.0°F (18.9°C)	Light Rain	Mostly Sunny	Average	Average
June	75.4°F (24.1°C)	Light Rain	Mostly Sunny	Slightly High	Average
July	78.1°F (25.6°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
August	76.1°F (24.5°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
September	70.2°F (21.2°C)	Light Rain	Mostly Sunny	Average	Average
October	58.5°F (14.7°C)	Light Rain	Mostly Sunny	Average	Average
November	46.0°F (7.8°C)	Light Rain	Mostly Sunny	Average	Slightly Low
December	38.1°F (3.4°C)	Light Rain	Mostly Sunny	Slightly Low	Average

The nearest major airports for your trip to St Mary

If you're planning to visit St. Mary, Missouri, two major airports serve the area: Williamson County Regional Airport (MWA) in Marion, IL, located 83.7km away, and Cape Girardeau Municipal Airport (CGI) in Cape Girardeau, MO, situated 80.5km from St. Mary. Nearby Marion hotels include the 3-star Drury Inn & Suites Marion, 3.2km from MWA, and the Baymont by Wyndham Marion, 4.8km away. In Cape Girardeau, consider the 3-star Drury Plaza Hotel Cape Girardeau Conference Center, 9.7km from CGI, or the Drury Inn & Suites Cape Girardeau, 8.0km away, for convenient accommodations.

Frequently asked questions

What is the best area to stay in St Mary?

The best area to stay in St Mary is the historic downtown area, particularly around Main Street and the surrounding blocks.This neighbourhood is the heart of St Mary, offering a convenient and pleasant base for visitors. You'll find a selection of local shops, eateries, and historic buildings, all within easy walking distance. The general layout is quite compact, making it simple to explore on foot.Couples looking for a relaxing getaway will appreciate the historic downtown. It provides a quiet setting with opportunities for leisurely strolls, enjoying local cuisine, and exploring the town's heritage. The proximity to the Mississippi River also offers scenic views and a chance for a peaceful walk along the riverfront.For travellers interested in local history and a sense of community, staying in the downtown area is ideal.

When is the best time to go to St Mary?

The best time to visit St Mary, Missouri, is during the spring (April to May) and autumn (September to October) months, when the weather is most pleasant for exploring.During these periods, the temperatures are mild and comfortable, making it ideal for outdoor activities like visiting the nearby state parks or exploring the historic downtown area. Spring brings blooming wildflowers, while autumn offers beautiful fall foliage, adding to the scenic appeal of the region.Families often find these seasons great for a trip. The milder weather makes it easier to enjoy attractions like the Mastodon State Historic Site or the hiking trails at Hawn State Park without the extreme heat of summer or the chill of winter. It's also a great time for leisurely strolls through the town, visiting local shops and eateries.For couples looking for a relaxed getaway, the spring and autumn months provide a tranquil setting. You can enjoy wine tasting at local vineyards or simply unwind in the peaceful surroundings.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in St Mary.

How much is the nightly rate at a St Mary hotel?

Prices for hotels in St Mary often vary, but you can find a great deal from CA $85 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Book Hotels in St Mary on Expedia.com

Find hotels in St Mary, MO from CA $85

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St Mary

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St Mary hotels

1. Baymont by Wyndham Chester IL

2. Microtel Inn & Suites by Wyndham Sainte Genevieve

3. Holiday Inn Express & Suites Perryville by IHG

4. Super 8 by Wyndham Perryville

5. Triangle Inn Motel

6. Perryville RV Resort

7. Days Inn by Wyndham Perryville

8. Quality Inn Perryville I-55

9. The Atrium - A Boutique Hotel

10. Red Bud Country Inn

11. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

12. The Conner House B&B

13. Holiday Inn Express Hotel & Suites Sparta by IHG

14. K-River Motel & Campground

15. Quality Inn Farmington

16. Baymont Inn and Suites by Wyndham Farmington, MO

17. Super 8 by Wyndham Farmington

18. Urban Lofts

19. Briarwood Inn of Sparta

20. Sparta Motel Near St. Louis / Mississippi River IL

Top St Mary Hotel Reviews

Holiday Inn Express & Suites Perryville by IHG

Madison Inn Lodge

Crown Pointe Lodge, BW Signature Collection

Super 8 by Wyndham Farmington

Private Hot Tub + Fire Pit | 4BR/2Bth Ranch | 10 Min to Historic Ste. Genevieve by Timber Oaks Vacation Rentals

Missouri Castle w/ Private Lake, Pool & 100 Acres!

Holiday Inn Express & Suites Farmington by IHG

Microtel Inn & Suites by Wyndham Sainte Genevieve

Silo Farm Haus- located in the heart of wine country!

More cheap stays in St Mary

Baymont Inn and Suites by Wyndham Farmington, MO

Super 8 by Wyndham Farmington

Super 8 by Wyndham Perryville

Baymont by Wyndham Chester IL

Holiday Inn Express & Suites Perryville by IHG

Crown Pointe Lodge, BW Signature Collection

Hotels in St Mary with star rating

Find out more about St Mary

Top reasons to visit St Mary

Find great hotels in St Mary

Where to stay in St Mary

Things to do in St Mary

Booking tips and Expedia advantages for St Mary

Find the best attractions in St Mary

Best time to go to St Mary

The nearest major airports for your trip to St Mary

Frequently asked questions

Explore a world of travel with Expedia