St Mary Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for St Mary vacation rentals

A single-story house with a front porch, a garage, and a well-maintained lawn.

1. Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve

Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
Saint Mary
9.8 out of 10, Exceptional, (12 reviews)
"The house was very clean. It's located in a quiet and safe neighborhood. It was well stocked with cooking utensils. It was pet friendly with a secure fenced backyard. The host was responsive and accommodating. We stayed here while we were in town for work and would stay here again."
United States
Deborah H.
The price is CA $201
CA $593 total
includes taxes & fees
Nov 17 - Nov 18
Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

2. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (12 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is CA $124
CA $142 total
includes taxes & fees
Nov 11 - Nov 12
The Atrium - A Boutique Hotel
A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.

3. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (119 reviews)
"Recomend this location"
United States
Jose
The price is CA $123
CA $204 total
includes taxes & fees
Dec 7 - Dec 8
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A white two-story house with a covered porch, a chimney, and a small garden area with chairs and a table.

4. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (296 reviews)
"Absolutely beautiful place to stay!! Very clean!"
United States
Jimmy B.
The price is CA $207
CA $271 total
includes taxes & fees
Nov 18 - Nov 19
Beautiful Modern Loft In Wine Country!
Exterior

5. Cozy 2-bedroom cottage in charming Ste. Genevieve

Cozy 2-bedroom cottage in charming Ste. Genevieve
Ste. Genevieve
9.8 out of 10, Exceptional, (9 reviews)
"Great location!"
United States
Katie M.
The price is CA $191
CA $226 total
includes taxes & fees
Dec 2 - Dec 3
Cozy 2-bedroom cottage in charming Ste. Genevieve
A cozy kitchen with two chairs, a small table with snacks, a coffee machine, and a view through a large window.

6. Vallee Suite at Baetje Farms

Vallee Suite at Baetje Farms
Bloomsdale
9.8 out of 10, Exceptional, (6 reviews)
"It was beautiful, quite and everything we expected!! Thanks for a great stay!!"
United States
Heather
The price is CA $133
CA $185 total
includes taxes & fees
Nov 8 - Nov 9
Vallee Suite at Baetje Farms
A room with two chairs, a table with a fruit platter, a hanging light fixture, and a view through a window with a curtain.

7. Amoureux Suite at Baetje Farms

Amoureux Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (1 review)
The price is CA $133
CA $185 total
includes taxes & fees
Nov 11 - Nov 12
Amoureux Suite at Baetje Farms
A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

8. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is CA $283
CA $436 total
includes taxes & fees
Nov 9 - Nov 10
Urban Lofts
A small, single-story building with a porch, a covered outdoor seating area, and a stone foundation.

9. 5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana

5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
Ste. Genevieve
10.0 out of 10, Exceptional, (4 reviews)
"Perfect size cabin to get away and enjoy nature sitting on front porch. Very clean with all the amenities you need. Erin was very nice and prompt response to any of my questions."
United States
Matt H.
The price is CA $266
CA $365 total
includes taxes & fees
Nov 11 - Nov 12
5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
A modern kitchen with dark wood cabinets, a central island, and a brick wall.

10. Downtown Urban Loft #9

Downtown Urban Loft #9
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"The Zen atmosphere made it really relaxing and the spa bathroom was incredible"
United States
Hunter
The price is CA $273
CA $429 total
includes taxes & fees
Nov 9 - Nov 10
Downtown Urban Loft #9
A small, single-story building with a porch, red chairs, and a fan.

11. 5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana

5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
New Offenburg
10.0 out of 10, Exceptional, (2 reviews)
"This was one of the best places I’ve ever stayed. Owner thought of everything and it was so comfortable. The space was perfect, extra blankets, both types of coffee makers, firewood on site. This is a very new property and everything was immaculate and clean. Was easy to navigate check-in and house was so cute! Would definitely recommend to anyone heading to St Gen or any of surrounding areas."
United States
Carole J.
The price is CA $266
CA $365 total
includes taxes & fees
Nov 11 - Nov 12
5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
A spacious loft with exposed brick walls, large windows, a kitchen with bar seating, and a ceiling fan.

12. Downtown Urban Loft #1

Downtown Urban Loft #1
Perryville
The price is CA $273
CA $429 total
includes taxes & fees
Nov 9 - Nov 10
Downtown Urban Loft #1
A modern cabin with a wooden deck, a spiral staircase, and a fireplace.

13. New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp
Perryville
10.0 out of 10, Exceptional, (9 reviews)
"Absolutely stunning oasis. Thank you, Waylon & Kaci, for such a beautifully-crafted, unique paradise."
United States
Brett H.
The price is CA $487
CA $745 total
includes taxes & fees
Dec 2 - Dec 3
New! Luxury Meets Nature - TreeRise at BaseCamp
A wooden treehouse with a glass window, surrounded by dense forest.

14. TreeLoft at BaseCamp

TreeLoft at BaseCamp
Perryville
10.0 out of 10, Exceptional, (5 reviews)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
The price is CA $484
CA $740 total
includes taxes & fees
Nov 24 - Nov 25
TreeLoft at BaseCamp
A hot tub with a wooden deck surrounding it, a window above, and a view of trees outside.

15. Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
Ste. Genevieve
10.0 out of 10, Exceptional, (63 reviews)
"Wonderful place to stay in Ste Genevieve wine country"
United States
Nicholas S.
The price is CA $378
CA $522 total
includes taxes & fees
Nov 11 - Nov 12
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
A two-story cylindrical building with a covered porch and a welcoming sign.

16. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (160 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
The price is CA $335
CA $519 total
includes taxes & fees
Nov 9 - Nov 10
Silo Farm Haus- located in the heart of wine country!
A modern house with a stone facade, large windows, and a porch with two chairs.

17. Coeur de la Crème Suite at Baetje Farms

Coeur de la Crème Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (3 reviews)
"It was super cozy and relaxed, the kind of place that makes you want to slow down and just hang out. Really warm vibe, almost like a little hidden getaway"
United States
Eric C.
The price is CA $140
CA $192 total
includes taxes & fees
Nov 11 - Nov 12
Coeur de la Crème Suite at Baetje Farms
A modern outdoor seating area with Adirondack chairs and a fire pit, surrounded by a gravel patio.

18. THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek

THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
Ste. Genevieve
10.0 out of 10, Exceptional, (13 reviews)
"Lovely place, communicative owners, would definitely stay there again!"
United States
Jana R.
The price is CA $276
CA $371 total
includes taxes & fees
Nov 11 - Nov 12
THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
A compact living space with a sofa, dining table, kitchen area, and a ceiling fan.

19. Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.4 out of 10, Exceptional, (11 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
The price is CA $100
CA $202 total
includes taxes & fees
Nov 9 - Nov 10
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Interior

20. The Cabin at Charleville

The Cabin at Charleville
Ste. Genevieve
The price is CA $414
CA $526 total
includes taxes & fees
Nov 17 - Nov 18
The Cabin at Charleville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Find vacation rentals that suit your style

cabin image
Cabins
Cabins
apart-hotel image
Aparthotels
Aparthotels

Top St Mary Hotel Reviews

A hotel lobby with a reception desk, seating area, and a patterned carpet.
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville

10/10 Excellent

Great Place to Stay! Customer so friendly and nice there!
Canada
Shavanie
Reviewed March 3, 2025
Holiday Inn Express & Suites Perryville by IHG

Frequently Asked Questions

Can I find vacation rentals in St Mary?

Yes, you can find vacation rentals close to the most popular local attractions in St Mary, or you can select a secluded option if you want a relaxing place to stay.

What's the top vacation rental in St Mary?

Private Hot Tub + Fire Pit | 4BR/2Bth Ranch | 10 Min to Historic Ste. Genevieve by Timber Oaks Vacation Rentals: Visitors give good reviews to this St Mary vacation home rental, which offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation. Our travelers also rate Missouri Castle w/ Private Lake, Pool & 100 Acres! as a favorite home for rent in St Mary.

What’s there to see and do in St Mary?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Popeye Museum and Felix Valle House State Historic Site.

What are vacation rentals like in St Mary?

Vacation rentals are private accommodations you can reserve for a short or long stay in St Mary. Vacation rentals feature extras like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.