Name: Best Western Plus Sikeston I-55
Price range: CA $131
Rating: 8.4

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East Prairie Hotel Deals

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Fully refundableReserve now, pay when you stay

CA $153

CA $176 total

Jun 21 - Jun 22

includes taxes & fees

9.6/10 Exceptional! (1,001 reviews)

"Breakfast was good,pool hot tub excellent"

Reviewed on May 17, 2026

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

CA $146

CA $165 total

Jun 7 - Jun 8

includes taxes & fees

9/10 Wonderful! (563 reviews)

"Everything was good"

Reviewed on May 10, 2026

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

Fully refundableReserve now, pay when you stay

CA $131

CA $149 total

Jun 8 - Jun 9

includes taxes & fees

8.4/10 Very Good! (1,000 reviews)

"Breakfast was fresh and the room was clean. It's a good place to stay. Friendly staff."

Reviewed on May 20, 2026

See all 89 properties in East Prairie

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.