
Find hotels in San Diego Santa Fe Depot, CA from CA $104
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay near San Diego Santa Fe Depot
Resort
Apart hotel
Check prices for these dates
Our top choices for San Diego Santa Fe Depot hotels

Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHGMission Valley
8.0 out of 10, Very good, (1,034 reviews)
The price is CA $152
CA $176 total
includes taxes & fees
May 10 - May 11

Sheraton San Diego Resort
Sheraton San Diego ResortHarbor Island
8.4 out of 10, Very good, (3,445 reviews)
The price is CA $204
CA $304 total
includes taxes & fees
May 10 - May 11

Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorldPoint Loma
7.4 out of 10, Good, (4,225 reviews)
The price is CA $136
CA $156 total
includes taxes & fees
Apr 12 - Apr 13

Westgate Hotel
Westgate HotelDowntown San Diego
9.2 out of 10, Wonderful, (1,008 reviews)
The price is CA $175
CA $251 total
includes taxes & fees
May 10 - May 11

Bahia Resort Hotel
Bahia Resort HotelCentral Mission Beach
8.6 out of 10, Excellent, (1,967 reviews)
The price is CA $220
CA $330 total
includes taxes & fees
May 10 - May 11

Wyndham San Diego Bayside
Wyndham San Diego BaysideDowntown San Diego
8.4 out of 10, Very good, (6,127 reviews)
The price is CA $211
CA $292 total
includes taxes & fees
May 10 - May 11

Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHGMission Hills
9.2 out of 10, Wonderful, (1,063 reviews)
The price is CA $195
CA $224 total
includes taxes & fees
Apr 26 - Apr 27

Hilton Garden Inn San Diego Old Town/SeaWorld Area
Hilton Garden Inn San Diego Old Town/SeaWorld AreaOld Town San Diego
8.8 out of 10, Excellent, (1,397 reviews)
The price is CA $201
CA $231 total
includes taxes & fees
Apr 26 - Apr 27

Hotel Narcissus
Hotel NarcissusLogan Heights
9.8 out of 10, Exceptional, (9 reviews)
The price is CA $101
CA $253 total
includes taxes & fees
Apr 22 - Apr 23

Best Western San Diego Pacific Beach/Mission Bay
Best Western San Diego Pacific Beach/Mission BayBay Park
8.2 out of 10, Very good, (339 reviews)
The price is CA $145
CA $167 total
includes taxes & fees
May 4 - May 5

Marriott Marquis San Diego Marina
Marriott Marquis San Diego MarinaDowntown San Diego
9.2 out of 10, Wonderful, (2,081 reviews)
The price is CA $331
CA $449 total
includes taxes & fees
May 1 - May 2

Best Western Plus Hacienda Hotel Old Town
Best Western Plus Hacienda Hotel Old TownOld Town San Diego
8.4 out of 10, Very good, (1,948 reviews)
The price is CA $186
CA $213 total
includes taxes & fees
Apr 26 - Apr 27

San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay
8.4 out of 10, Very good, (1,392 reviews)
The price is CA $242
CA $351 total
includes taxes & fees
May 10 - May 11

Kings Inn San Diego
Kings Inn San DiegoMission Valley
8.8 out of 10, Excellent, (3,667 reviews)
The price is CA $131
CA $151 total
includes taxes & fees
Apr 27 - Apr 28

Lafayette Hotel & Club
Lafayette Hotel & ClubUniversity Heights
9.2 out of 10, Wonderful, (1,571 reviews)
The price is CA $345
CA $396 total
includes taxes & fees
Apr 16 - Apr 17

Hilton San Diego Bayfront
Hilton San Diego BayfrontDowntown San Diego
8.6 out of 10, Excellent, (2,024 reviews)
The price is CA $282
CA $395 total
includes taxes & fees
May 10 - May 11

Bay Club Hotel & Marina
Bay Club Hotel & MarinaPoint Loma
9.2 out of 10, Wonderful, (3,532 reviews)
The price is CA $228
CA $262 total
includes taxes & fees
Apr 27 - Apr 28

Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty StationSan Diego
9.2 out of 10, Wonderful, (1,713 reviews)
The price is CA $230
CA $265 total
includes taxes & fees
Apr 26 - Apr 27

The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier CollectionDowntown San Diego
8.8 out of 10, Excellent, (1,340 reviews)
The price is CA $187
CA $217 total
includes taxes & fees
Apr 27 - Apr 28

Comfort Inn Sea World Area
Comfort Inn Sea World AreaPoint Loma
8.6 out of 10, Excellent, (3,567 reviews)
The price is CA $147
CA $169 total
includes taxes & fees
May 10 - May 11
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in San Diego Santa Fe Depot
Aparthotel

Little Italy Inn - Limited Service Apart Hotel
Little Italy Inn - Limited Service Apart HotelDowntown San Diego
8.4 out of 10, Very good, (117 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Top San Diego Santa Fe Depot Hotel Reviews
Recent Reviews in San Diego Santa Fe Depot

Paradise Point Resort & Spa
10/10 Excellent
More cheap stays in San Diego Santa Fe Depot

Heritage Inn San Diego
3333 Channel Way San Diego CA
The price is CA $90 per night from Apr 12 to Apr 13
CA $90
CA $104 total
Apr 12 - Apr 13
includes taxes & fees
7.4/10 Good! (1,365 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in San Diego
- Hotels near 5th Avenue Station
- Hotels near B Street Cruise Ship Terminal
- Apartments in Civic Center Station
- Hotels near Civic Center Station
- Beach Hotel Hotels in Columbia
- Boutique Hotels in Columbia
- Cheap Hotels in Columbia
- Hotels with Kitchenettes in Columbia
- Columbia Hotels
- Hotels near Convention Center Station
- Hotels near Copley Symphony Hall
- Cortez Hill Hotels
- All Inclusive Resorts and in San Diego County
- Beach Hotel Hotels in San Diego County
- Casino Hotels in San Diego County
- Cheap Hotels in San Diego County
- Family Hotels in San Diego County
- Golf Hotels in San Diego County
- Hotels with Free Airport Shuttle in San Diego County
- Hotels with Waterslides in San Diego County
- Luxury Hotels in San Diego County
- Oceanfront Hotels in San Diego County
- San Diego County Hotels
- Cheap Hotels in Downtown San Diego
- Hotels with Free Parking in Downtown San Diego
- Oceanfront Hotels in Downtown San Diego
- Downtown San Diego Hotels
- East Village Hotels
- Gaslamp Quarter Hotels
- Hotels near Gaslamp Quarter Station
- Harborview Hotels
- Little Italy Hotels
- All Inclusive Resorts and in Marina District
- Cheap Hotels in Marina District
- Golf Hotels in Marina District
- Hotels with Balconies in Marina District
- Hotels with an Indoor Pool in Marina District
- Oceanfront Hotels in Marina District
- Spa Hotels in Marina District
- Marina District Hotels
- Hotels near Maritime Museum of San Diego
- Hotels near Navy Pier
- Hotels near New Children's Museum
- Hotels near Petco Park
- Hotels near Port of San Diego
- Hotels near San Diego Civic Theatre
- Hotels near San Diego Convention Center
- Resorts in San Diego County
- Hostels in San Diego
- All Inclusive Resorts and in San Diego
- Cheap Hotels in San Diego
- Hotels with Free Airport Shuttle in San Diego
- Hotels with Free Breakfast in San Diego
- Hotels with Kitchenettes in San Diego
- San Diego Hotels
- Hotels near San Diego Intl.
- Hotels near Seaport Village
- B&B in Seaport Village Station
- Hotels near Seaport Village Station
- Resorts in Seaport Village Station
- Hotels near Star of India
- Hotels near The Rady Shell at Jacobs Park
- Hotels near USS Midway Museum
- Hotels near Waterfront Park
- Flights to San Diego
- Flights to San Diego County
- Flights from Toronto to San Diego
- Flights from Edmonton to San Diego
- Flights from Kelowna to San Diego
- Flights from Regina to San Diego
- Flights from Los Angeles (LAX) to San Diego (SAN)
- Flights from Edmonton (YEG) to San Diego (SAN)
- Flights from Montreal (YUL) to San Diego (SAN)
- Flights from Vancouver (YVR) to San Diego (SAN)
- Flights from Calgary (YYC) to San Diego (SAN)
- Flights from Toronto (YYZ) to San Diego (SAN)
- Avis Rental Cars in Downtown San Diego
- Car rentals near B Street Cruise Ship Terminal
- Car rentals near Downtown San Diego
- Car rentals near Port of San Diego
- Rental cars San Diego Intl. airport
- Car rental San Diego
- Car rentals near San Diego County
- Luxury Car Rentals near USS Midway Museum
- Suv Car Rentals near USS Midway Museum



























































































































