Title: Top Hotels in New Madrid County | Expedia.ca [Vacation Rentals in New Madrid County](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Vacation-Rental-Destinations)[New Madrid County Car Rentals](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Car-Rental-Destinations)[New Madrid County Vacations](https://expedia.ca/New-Madrid-County.d553248635976433157.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in New Madrid County ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Sikeston [](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) ![Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. . ](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### New Madrid [](https://expedia.ca/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Feb 10 - Feb 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 11 - Feb 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for New Madrid County hotels ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,004 reviews) "As always it was a perfect visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $122 CA $140 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,004 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $115 CA $131 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (478 reviews) "Great place for an overnight stay. I will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny CA $129 CA $146 total includes taxes & fees Feb 28 - Mar 1 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,001 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $92 CA $105 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/a2f06e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/0c032f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/d0c3544f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "Rooms were very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lydia [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (735 reviews) "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky CA $79 CA $90 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very good (740 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (56 reviews) "Clean rooms great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) IRA CA $137 CA $155 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/55187aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/97dfc357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) Sikeston 6.8/10 (593 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Misty CA $81 CA $92 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/ef46b494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) Marston 8.0/10 Very good (45 reviews) "Great hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dmitry CA $88 CA $100 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/5bb06af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/6099e00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/f23217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/501c540f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) Marston 6.0/10 (118 reviews) "Had a great time loved it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shyianne CA $68 CA $77 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (447 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney CA $149 CA $169 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.2/10 Wonderful (12 reviews) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $195 CA $221 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-f34c7d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1907x0y6-58887435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2274h1520x153y0-deab61df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1905x0y7-6be09486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Malden Airport Inn [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) Malden 7.0/10 Good (68 reviews) "Clean room, quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/07d69819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/1fa29b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very good (286 reviews) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen CA $123 CA $140 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.6/10 (122 reviews) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $59 CA $71 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1060h720x0y199-6f809fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h1439x0y1-2bafdfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/18e1eee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h809x0y1-d7340261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room! [](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) New Madrid 10/10 Exceptional (1 review) "The host was very quick to respond and so great to work with for on our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica S. CA $271 CA $462 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/aab8c593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/ee2b7138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/6045fc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Cozy Apartment with large windows and sunlight. [](https://www.expedia.ca/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handicap Room](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/6128b6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/60633b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) Tiptonville 7.2/10 Good (465 reviews) "Nice in clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jayla CA $80 CA $92 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/0d61a825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/342c28ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/5fe9a626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/8341e2b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny house on the lake with tv free internet walk shower [](https://www.expedia.ca/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information) Tiptonville 10/10 Exceptional (1 review) "Dave was very accommodating and the home was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine P. CA $183 CA $339 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=553248635976433157&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ## Top New Madrid County Hotel Reviews ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "The desk clerk was very welcoming. The hotel was clean and our room was nice. Good breakfast selection. Would definitely stay here again if in the area." [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Yes" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg) ### The Farmstead Hotel 10/10 Excellent "room was good and staff were nice but they arent joking in the listing that you will hear everything. wont stop me from coming back though. defiently the best hotel in the area." [](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![Drury Inn & Suites Hayti Caruthersville](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031_y.jpg) ### Drury Inn & Suites Hayti Caruthersville 10/10 Excellent "Room was clean and comfortable. Bathroom was clean. Addition of drinks/appetizers for a few hours in the evening is nice. The breakfast was also a nice addition. We would definitely stay again. " [](https://expedia.ca/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Great" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg) ### Super 8 by Wyndham Sikeston/Miner Area 10/10 Excellent "Greatness" [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Clean comfy stay ! Thanks" [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 10/10 Excellent "Clean rooms great staff" [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in New Madrid County - [Marston Hotels ](https://expedia.ca/Marston-Hotels.d55824.Travel-Guide-Hotels) - [New Madrid Hotels ](https://expedia.ca/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Matthews Hotels ](https://expedia.ca/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Gideon Hotels ](https://expedia.ca/Gideon-Hotels.d3000349377.Travel-Guide-Hotels) - [Lilbourn Hotels ](https://expedia.ca/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels) - [Morehouse Hotels ](https://expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [Risco Hotels ](https://expedia.ca/Risco-Hotels.d3000349516.Travel-Guide-Hotels) - [Tallapoosa Hotels ](https://expedia.ca/Tallapoosa-Hotels.d553248634983263480.Travel-Guide-Hotels) - [Howardville Hotels ](https://expedia.ca/Howardville-Hotels.d553248634983363505.Travel-Guide-Hotels) - [Canalou Hotels ](https://expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near New Madrid Historical Museum ](https://expedia.ca/New-Madrid-Historical-Museum-Hotels.0-l553248621532655748-0.Travel-Guide-Filter-Hotels) - [Hotels near Marston Community Center ](https://expedia.ca/Marston-Community-Center-Hotels.0-l553248622945532712-0.Travel-Guide-Filter-Hotels) - [Hotels near River Ridge Winery ](https://expedia.ca/River-Ridge-Winery-Hotels.0-l553248621532655749-0.Travel-Guide-Filter-Hotels) - [Hotels near Hunter-Dawson State Historic Site ](https://expedia.ca/Hunter-Dawson-State-Historic-Site-Hotels.0-l553248621532655794-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River ](https://expedia.ca/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake ](https://expedia.ca/Reelfoot-Lake-Hotels.0-l553248635976195913-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake State Park ](https://expedia.ca/Reelfoot-Lake-State-Park-Hotels.0-l553248621532655205-0.Travel-Guide-Filter-Hotels) - [Hotels near Century Casino Caruthersville ](https://expedia.ca/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels) - [Hotels near Hayti Park ](https://expedia.ca/Hayti-Park-Hotels.0-l6245776-0.Travel-Guide-Filter-Hotels) - [Hotels near The Heritage House ](https://expedia.ca/The-Heritage-House-Hotels.0-l553248621592342444-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in New Madrid County - [Vacation Homes in New Madrid County ](https://expedia.ca/New-Madrid-County-Private-Vacation-Homes.d553248635976433157-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Lodges in New Madrid County ](https://expedia.ca/New-Madrid-County-Lodges.d553248635976433157-aaLodges.Travel-Guide-Accommodation) - [Motels in New Madrid County ](https://expedia.ca/New-Madrid-County-Motels.d553248635976433157-aaMotels.Travel-Guide-Accommodation) - [Cottages in New Madrid County ](https://expedia.ca/New-Madrid-County-Cottages.d553248635976433157-aaCottages.Travel-Guide-Accommodation) - [Apartments in New Madrid County ](https://expedia.ca/New-Madrid-County-Apartments.d553248635976433157-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in New Madrid County ](https://expedia.ca/New-Madrid-County-Cabins.d553248635976433157-aaCabins.Travel-Guide-Accommodation) - [RV Parks in New Madrid County ](https://expedia.ca/New-Madrid-County-RV-Parks.d553248635976433157-aaRVParks.Travel-Guide-Accommodation) ### Explore more hotels - [Hampton Inn Sikeston ](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) - [Fairfield Inn & Suites by Marriott Sikeston ](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) - [New Orleans Inn Portageville ](https://expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) - [Super 8 By Wyndham Marston ](https://expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) - [Holiday Inn Express & Suites Sikeston Southwest by IHG ](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) - [Travel Inn ](https://expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) - [TownePlace Suites by Marriott Sikeston ](https://expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) - [Drury Inn & Suites Sikeston, MO ](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) - [The Farmstead Hotel ](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) - [Drury Inn & Suites Hayti Caruthersville ](https://expedia.ca/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information) [See a list of all hotels in New Madrid County](https://expedia.ca/All-New-Madrid-County-Hotels.d553248635976433157.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in New Madrid County on Expedia.com ](https://www.expedia.com/Destinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Best Hotels in Wentzville](https://expedia.ca/Wentzville-Hotels.d7679.Travel-Guide-Hotels) - 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[Visit Downtown St. Louis](https://expedia.ca/St-Louis-Downtown-St-Louis.dx800136) - [Visit Downtown Kansas City](https://expedia.ca/Kansas-City-Downtown-Kansas-City.dx6058828) - [Visit Parkville](https://expedia.ca/Parkville.dx9973) - [Visit River Market](https://expedia.ca/Kansas-City-River-Market.dx6192918) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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