Title: Book The Best Hotels in Matthews, MO for 2026 from CA $78 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Matthews](https://expedia.ca/Matthews-Vacation-Rentals.d553248634983428760.Travel-Guide-VacationRentals)[Matthews Car Rentals](https://expedia.ca/Car-Rentals-In-Matthews.d553248634983428760.Car-Rental-Guide)[Matthews Vacation Packages](https://expedia.ca/Matthews.d553248634983428760.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Matthews, MO from CA $78 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Matthews Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Matthews%2C+Missouri%2C+United+States+of+America®ionId=553248634983428760&latLong=36.759222%2C-89.586746&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&travelerType=family_friendly) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Matthews%2C+Missouri%2C+United+States+of+America®ionId=553248634983428760&latLong=36.759222%2C-89.586746&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Matthews%2C+Missouri%2C+United+States+of+America®ionId=553248634983428760&latLong=36.759222%2C-89.586746&adults=2&startDate=2026-01-15&d1=2026-01-15&endDate=2026-01-17&d2=2026-01-17&amenities=POOL) ## Check prices for these dates Tonight [Jan 1 - Jan 2](https://www.expedia.ca/Hotel-Search?regionId=553248634983428760&startDate=2026-01-01&endDate=2026-01-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=553248634983428760&startDate=2026-01-02&endDate=2026-01-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983428760&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983428760&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Matthews hotels ![Reception](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-e5745fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/68a43d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1907x0y6-58887435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/51b0d3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Malden Airport Inn [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) Malden 7.0/10 Good (68) "Clean room, quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/6497a67e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/cb936040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/59b72b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Dexter [](https://www.expedia.ca/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) Dexter 6.8/10 (253) "The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $81 CA $91 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/eea0b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/f5deab1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8865f485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Dexter [](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) Dexter 7.6/10 Good (390) "Clean room, friendly staff and quiet stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margo CA $107 CA $120 total includes taxes & fees Jan 2 - Jan 3 [](https://www.expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1002) "Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $86 CA $98 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) Sikeston 6.8/10 (570) "Excellent check-in process! Extremely friendly staff. Room is very adequate. Everything you need. Price was a great bargain." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald CA $81 CA $93 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Studio, 1 King Bed](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn By Hilton Dexter [](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) Dexter 10/10 Exceptional (5) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $145 CA $163 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d663210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking (Mobility, Roll-in Shower)](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/a7ce909b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/e6403655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) Marston 7.8/10 Good (39) "Great hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dmitry CA $79 CA $90 total includes taxes & fees Jan 4 - Jan 5 [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (456) "clean room, comfy bedding, nice staff, convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexa CA $140 CA $158 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1005) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $106 CA $121 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/664c9838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5be64f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very good (283) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen CA $121 CA $138 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/5704c6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/02df00ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/012f90a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self parking](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/21db18b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hickory House Inn [](https://www.expedia.ca/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) Dexter 5.6/10 (134) "We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert [](https://www.expedia.ca/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1004) "Great place. Friendly staff clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff CA $123 CA $142 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/501c540f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/6099e00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/a3f1cfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/825a993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) Marston 6.0/10 (116) "Had a great time loved it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shyianne CA $69 CA $78 total includes taxes & fees Jan 2 - Jan 3 [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (445) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney CA $127 CA $144 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/8fbe165c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/f3b3697d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/00fa2fb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/9a624d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Inn [](https://www.expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) Dexter 7.0/10 Good (333) "Room was nice and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $89 CA $100 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/e7b8b662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (726) "Clean room and easy access to room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne CA $76 CA $87 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (45) "THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AHMAD CA $150 CA $170 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (121) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $73 CA $87 total includes taxes & fees Jan 2 - Jan 3 [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.0/10 Wonderful (10) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $168 CA $190 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.6/10 (615) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $85 CA $95 total includes taxes & fees Jan 2 - Jan 3 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-15&endDate=2026-01-16®ionId=553248634983428760&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMatthews-Hotels.d553248634983428760.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMatthews-Hotels.d553248634983428760.Travel-Guide-Hotels) ## More cheap stays in Matthews ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 100 Matthews Lane Sikeston MO CA $76 CA $87 total Jan 20 - Jan 21 includes taxes & fees 8.4/10 Very Good! (723 reviews) [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO CA $86 CA $98 total Jan 27 - Jan 28 includes taxes & fees 7.2/10 Good! (1,002 reviews) [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Sikeston 2602 E Malone Avenue Sikeston MO CA $103 CA $118 total Jan 25 - Jan 26 includes taxes & fees 9.2/10 Wonderful! (1,003 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Sikeston 120 S Interstate Drive Sikeston MO CA $106 CA $121 total Jan 6 - Jan 7 includes taxes & fees 8.2/10 Very Good! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO CA $140 CA $158 total Jan 11 - Jan 12 includes taxes & fees 8.8/10 Excellent! (452 reviews) [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Sikeston 1239 Commerce Drive Sikeston MO CA $150 CA $170 total Jan 6 - Jan 7 includes taxes & fees 9.2/10 Wonderful! (43 reviews) [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ## Hotels in Matthews with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 3 properties [](https://expedia.ca/3Star-Matthews-Hotels.s30-0-d553248634983428760.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 22 properties [](https://expedia.ca/2Star-Matthews-Hotels.s20-0-d553248634983428760.Travel-Guide-Filter-Hotels) ## Find out more about Matthews ### Top reasons to visit Matthews - **Outdoor Adventures:** Matthews is a haven for outdoor enthusiasts, offering stunning nature trails, hiking, and fishing opportunities amidst beautiful scenery. - **Local Attractions:** Explore unique venues, including history museums and parks that showcase the region's culture and heritage. - **Family-Friendly Atmosphere:** With a welcoming vibe and diverse activities, Matthews is perfect for family excursions throughout the year. - **Budget-Friendly Accommodations:** Enjoy a variety of 2 to 2.5-star hotels that cater to families and business travellers alike. - **Charming Landscapes:** Immerse yourself in Matthews' picturesque surroundings, ideal for relaxation and exploration. ### Find great hotels in Matthews Matthews, Missouri, offers an array of budget-friendly hotel accommodations, primarily featuring 2 to 2.5-star options. Whether you're travelling with family, on a business trip, or seeking pet-friendly amenities, you'll discover a variety of lodging types designed to enhance your stay. From comfortable rooms to essential services, Matthews has something for every traveller looking to explore this charming area. - **[Days Inn and Suites by Wyndham Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)** This hotel offers a welcoming atmosphere for both business and pet-friendly travellers, located 14.5km from Matthews. With a focus on convenience, it features multiple meeting rooms equipped for business needs, making it ideal for corporate stays. Additionally, the property is accommodating to pets with specific restrictions, allowing dogs and cats, ensuring that your furry companions can join you on your journey. Guests appreciate the comfortable rooms and the overall commitment to providing a practical experience for those on the go. - **[Pear Tree Inn Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)** Situated 16.1km from Matthews, Pear Tree Inn Sikeston is perfect for families and business travellers alike. Its family-friendly amenities include free cribs for infants, making it an excellent choice for those travelling with children. The hotel also offers a business centre for professionals needing to stay connected. Pet owners will be pleased to know that the property allows dogs and cats with some restrictions, ensuring your pets are welcome companions during your stay. The warm and inviting atmosphere makes it a wonderful retreat for all guests. - **[Best Western Plus Sikeston:](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)** Located 16.1km from Matthews, Best Western Plus Sikeston is a great choice for pet lovers seeking a comfortable stay. This hotel combines modern amenities with a pet-friendly policy, allowing pets with specific restrictions, ensuring your fur babies can enjoy the trip too. Guests appreciate the spacious accommodations and the hotel’s commitment to service, making it an ideal base for exploring the area. With a focus on comfort and convenience, this hotel is well-suited for both leisure and business travellers. ### Where to stay in Matthews Matthews, Missouri, offers a delightful blend of outdoor adventures and charming scenery perfect for family-friendly excursions. With its friendly atmosphere and a mix of weather conditions—from heavy snow to sunny days—visitors can enjoy a variety of activities year-round. Explore nearby cities and neighborhoods, where you’ll find welcoming locals and a budget-friendly vibe, making your vacation both enjoyable and memorable. - **[Sikeston:](https://www.expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)** Located a mere 12.9km from Matthews, Sikeston is a vibrant city that attracts visitors year-round, with peak travel occurring during the summer months. Known for its outdoor adventures and picturesque scenery, Sikeston offers activities that cater to both romance seekers and families. Enjoy the recreational areas, try your luck at the local casino, or catch a show at the arena entertainment facility. Nature lovers will appreciate the nearby lakes and national parks, making Sikeston a delightful stop for those looking to immerse themselves in the great outdoors. - **[Canalou:](https://www.expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels)** Just 9.7km from Matthews, Canalou is a charming city that boasts a steady flow of visitors throughout the year. While it may not have the same level of tourist attractions as larger cities, its quaint atmosphere offers a unique travel experience. Spend some time exploring the local community and enjoy the laid-back vibe that Canalou has to offer. The area is perfect for those who appreciate a slower pace and a taste of authentic small-town life. - **[Miner:](https://www.expedia.ca/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels)** Situated 16.1km from Matthews, Miner is a welcoming village ideal for families and outdoor enthusiasts. With peak travel times in January and the summer months, this village offers a blend of recreational activities, shopping, and community events. Visitors can explore the local stores, enjoy the recreational areas, and take advantage of nearby landmarks like lakes and national state parks. Whether you're looking for family-friendly fun or simply want to soak in the scenery, Miner has something for everyone. ### Things to do in Matthews Matthews, Missouri, offers a delightful escape for outdoor enthusiasts, boasting beautiful scenery and exciting adventures. Visitors can explore nature trails, enjoy recreational activities, and immerse themselves in the charming landscapes. Whether you’re hiking, fishing, or simply taking in the sights, Matthews provides a perfect backdrop for a memorable vacation experience. Embrace the great outdoors and discover the natural beauty that this hidden gem has to offer. **Shopping** The Book Bug, located 14.5km away from Matthews, offers a delightful selection of books and unique gifts. If you're up for a drive, there are larger shopping malls nearby that provide a wider variety of stores and boutiques for all your souvenir needs. **Recreation** At [Boot Heel Golf Club](https://www.expedia.ca/Boot-Heel-Golf-Club-Hotels.0-l6305606-0.Travel-Guide-Filter-Hotels), located 16.1km from Matthews, enjoy a round of golf amid beautiful outdoor scenery. The club’s inviting atmosphere provides a perfect blend of sport and relaxation, making it an ideal retreat for both golf enthusiasts and those seeking a refreshing day outdoors. ### Booking tips and Expedia advantages for Matthews Matthews, Missouri, offers budget-friendly travel options for Canadian tourists. To save on accommodation, visit between December and February, when prices are lower, particularly on Tuesdays. Utilize Expedia to find eco-certified hotels and arrange your stay by price for the best deals. Consider combining hotel, flight, and activity bookings for additional savings. For transportation, walking, biking, or renting a car are viable options. Explore free local attractions to stretch your budget further and ensure you check the weather forecast to pack appropriately. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Matthews are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Matthews is Tuesday. The most expensive day to stay in Matthews is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred type of accommodation. For instance, selecting the "Eco-certified" filter will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and offers, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save some money by combining your hotel stay in Matthews with your flights and activities when you book an Expedia package. ### Find the best attractions in Matthews Matthews, Missouri, is an ideal destination for outdoor enthusiasts and adventure seekers, offering stunning scenery and a variety of activities. Visitors can explore local attractions such as event conference venues, national and state parks, and history museums. Whether you’re interested in culture, outdoor experiences, or business opportunities, Matthews provides a diverse range of points of interest that cater to every type of traveller, ensuring a memorable vacation experience. - **[Sikeston Depot Museum:](https://www.expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)** Explore the rich history and culture of the region at the Sikeston Depot Museum, an art museum located 12.9km from Matthews. The museum showcases local art and historical exhibits, providing a unique glimpse into the area's heritage. - **[Central Park:](https://www.expedia.ca/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)** Enjoy a family-friendly atmosphere at Central Park, an urban park also 12.9km away. With its spacious green areas, playgrounds, and walking trails, it’s perfect for outdoor activities and relaxation amidst the city vibes. - **[Hunter-Dawson State Historic Site:](https://www.expedia.ca/Hunter-Dawson-State-Historic-Site-Hotels.0-l553248621532655794-0.Travel-Guide-Filter-Hotels)** Discover the charm of the Hunter-Dawson State Historic Site, a historic house situated 19.3km from Matthews. This site reflects the cultural heritage of the region, offering guided tours that delve into its fascinating past. ### Best time to go to Matthews Visitor numbers in Matthews is generally unchanged in popularity throughout the year. The best time to visit Matthews can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Matthews falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Matthews falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 36.1°F (2.3°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 39.2°F (4.0°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average | | April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Average | | June | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average | | October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Average | Average | | November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Average | Average | | December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Matthews When visiting Matthews, Missouri, you have a few airport options to consider. Paducah, KY (PAH-Barkley Regional) is situated 80.5km away, with nearby accommodations like [The Respite Bed and Breakfast](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information), a charming 4.5-star B&B located 14.5km from the airport. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is closer at 51.5km, featuring hotels such as Drury Plaza Hotel, just 9.7km away. Cairo, IL (CIR-Cairo Regional) is another option, located 214.5km from Matthews, with the [Quality Inn Cairo I-57](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) being 3.2km from the airport. Each location offers various transport services for easy access to Matthews. ## Recent reviews of Matthews hotels ![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg) ### Super 8 by Wyndham Sikeston/Miner Area 5/5 Excellent "Excellent check-in process! Extremely friendly staff. Room is very adequate. Everything you need. Price was a great bargain." A verified traveller stayed at Super 8 by Wyndham Sikeston/Miner Area Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Hampton Inn By Hilton Dexter](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2_y.jpg) ### Hampton Inn By Hilton Dexter 5/5 Excellent "Everything was brand new and super clean. The staff were all friendly. Good location , beautiful decor" A verified traveller stayed at Hampton Inn By Hilton Dexter Posted 6 days ago [](https://expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Travelodge by Wyndham Dexter](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86_y.jpg) ### Travelodge by Wyndham Dexter 5/5 Excellent "Great Staff, Easy Check-in & Check-out!!! Bed was extremely comfortable and loved the variety in cable channels…The only recommendation would be the shower towels be a little thicker…" A verified traveller stayed at Travelodge by Wyndham Dexter Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da_y.jpg) ### Holiday Inn Express & Suites Sikeston Southwest by IHG 5/5 Excellent "Stay was excellent " A verified traveller stayed at Holiday Inn Express & Suites Sikeston Southwest by IHG Posted 6 days ago [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 5/5 Excellent "Rooms are clean and location is very convenient. " A verified traveller stayed at Fairfield Inn & Suites by Marriott Sikeston Posted 7 days ago [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 5/5 Excellent "Great place to stay to stop over for the night. Very clean. Great value. " A verified traveller stayed at Best Western Plus Sikeston Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 5/5 Excellent "Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays." A verified traveller stayed at Days Inn and Suites by Wyndham Sikeston Posted 9 days ago [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 5/5 Excellent "clean room, comfy bedding, nice staff, convenient location " A verified traveller stayed at Hampton Inn Sikeston Posted 9 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 5/5 Excellent "Affordable and confortable" A verified traveller stayed at Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Posted 10 days ago [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Matthews hotel booking with Expedia? ### How much is the nightly rate at a Matthews hotel? ## Explore a world of travel with Expedia - 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