Find hotels in Southern Minnesota, MN from CA $89

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Compare 1,177 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Southern Minnesota hotels

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very good, (1528)
"It was a very comfortable and clean place to stay."
The price is CA $178
CA $204 total
includes taxes & fees
Aug 23 - Aug 24
Kahler Grand Hotel

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.2 out of 10, Good, (1002)
"Loved the kid area in the pool"
The price is CA $100
CA $115 total
includes taxes & fees
Aug 24 - Aug 25
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
8.0 out of 10, Very good, (988)
"It was in a good location near the downtown."
The price is CA $105
CA $121 total
includes taxes & fees
Aug 26 - Aug 27
AmericInn by Wyndham Rochester Near Mayo Clinic

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (873)
"Excellent and very clean property, beds were amazing "
The price is CA $172
CA $201 total
includes taxes & fees
Aug 24 - Aug 25
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Aspen Suites

3.0 star property
9.0 out of 10, Wonderful, (642)
"Convenient and nice hotel. "
The price is CA $186
CA $236 total
includes taxes & fees
Aug 23 - Aug 24
Aspen Suites

The Plaza Hotel & Suites Winona

3.0 star property
8.8 out of 10, Excellent, (1000)
"Overall great location and restaurant connection to the hotel Pool is amazing "
The price is CA $223
CA $248 total
includes taxes & fees
Aug 26 - Aug 27
The Plaza Hotel & Suites Winona

AmericInn by Wyndham Lake City

2.5 star property
9.0 out of 10, Wonderful, (580)
"I love the location and the view. "
The price is CA $160
CA $176 total
includes taxes & fees
Sep 14 - Sep 15
AmericInn by Wyndham Lake City

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (813)
"Great place, staff was friendly. Beds were comfortable. Would stay again. "
The price is CA $107
CA $127 total
includes taxes & fees
Sep 12 - Sep 13
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
8.2 out of 10, Very good, (702)
"Nice place to stay"
The price is CA $118
CA $135 total
includes taxes & fees
Aug 27 - Aug 28
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Ramada by Wyndham Albert Lea

3.0 star property
7.4 out of 10, Good, (1002)
"Quiet, clean, great staff"
The price is CA $103
CA $114 total
includes taxes & fees
Sep 7 - Sep 8
Ramada by Wyndham Albert Lea

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
8.4 out of 10, Very good, (1002)
"Great place "
The price is CA $171
CA $197 total
includes taxes & fees
Aug 23 - Aug 24
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
8.4 out of 10, Very good, (1001)
"Nice and quiet neighborhood, but still conveniently located to wherever you need to go."
The price is CA $111
CA $128 total
includes taxes & fees
Sep 14 - Sep 15
Country Inn & Suites Rochester South Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
8.0 out of 10, Very good, (1002)
"I liked the quietness, cleanliness, and the breakfasts. The bus stop is ever so close. I was happy to see Mayo Clinic is within walking distance.l enjoyed my stay."
The price is CA $92
CA $106 total
includes taxes & fees
Sep 5 - Sep 6
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Mankato

2.0 star property
7.8 out of 10, Good, (1003)
"Very nice hotel"
The price is CA $85
CA $94 total
includes taxes & fees
Aug 31 - Sep 1
Microtel Inn & Suites by Wyndham Mankato

AmericInn by Wyndham Winona

2.5 star property
9.0 out of 10, Wonderful, (834)
"Looks new or newly renovated, nice property, very clean rooms, great breakfast."
The price is CA $171
CA $191 total
includes taxes & fees
Aug 24 - Aug 25
AmericInn by Wyndham Winona

St James Hotel, a Historic Hotel of America

3.5 star property
9.2 out of 10, Wonderful, (1000)
"A historic hotel ! "
The price is CA $224
CA $256 total
includes taxes & fees
Aug 24 - Aug 25
St James Hotel, a Historic Hotel of America

Med City Inn & Suites - Mayo Clinic Area

2.5 star property
7.8 out of 10, Good, (1002)
"Nice place to stay "
The price is CA $111
CA $128 total
includes taxes & fees
Aug 23 - Aug 24
Med City Inn & Suites - Mayo Clinic Area

Holiday Inn Express Rochester South - Mayo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (1002)
"Great staff and nice clean convenient hotel "
The price is CA $111
CA $128 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express Rochester South - Mayo Area by IHG

Aspen Select

3.5 star property
8.4 out of 10, Very good, (1001)
"great receptionist ! "
The price is CA $156
CA $189 total
includes taxes & fees
Aug 23 - Aug 24
Aspen Select

Country Inn & Suites by Radisson, Rochester, MN

2.5 star property
7.6 out of 10, Good, (1003)
"Friendly staff and great rate "
The price is CA $94
CA $108 total
includes taxes & fees
Aug 31 - Sep 1
Country Inn & Suites by Radisson, Rochester, MN
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Minnesota, MN

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Family-friendly hotels in Southern Minnesota you'll enjoy

Hotels with a water park in Southern Minnesota may fit your trip

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Learn more about Southern Minnesota

Discover the family-friendly area of Southern Minnesota—an opera house, a college vibe, and sights from Mount Kato Ski Area to Blakeslee Stadium.

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Open Photo by Howard Lower Photography

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