Title: Book the Best Southern Minnesota LUXURY Hotels - Upscale Hotels in Southern Minnesota, MN | Expedia.ca [Southern Minnesota Travel Guide](https://expedia.ca/Southern-Minnesota.dx6059950)[Hotels in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[Vacation Rentals in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Vacation-Rentals.d6059950.Travel-Guide-VacationRentals)[Flights to Southern Minnesota](https://expedia.ca/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Minnesota.d6059950.Car-Rental-Guide)[Southern Minnesota Vacation Packages](https://expedia.ca/Southern-Minnesota.d6059950.Destination-Travel-Guides) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Minnesota Luxury Hotels Tonight [Jan 20 - Jan 21](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-01-20&endDate=2026-01-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-01-21&endDate=2026-01-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-01-30&endDate=2026-02-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Southern Minnesota luxury hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/978fdbcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/3144e2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/c5ed6677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/acf22658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Towers At Kahler Grand Hotel [](https://www.expedia.ca/Rochester-Hotels-The-Towers-At-Kahler-Grand-Hotel.h16119557.Hotel-Information) Downtown Rochester 9.4/10 Exceptional (96 reviews) "Excellent accommodations, amazing staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon CA $602 CA $693 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Rochester-Hotels-The-Towers-At-Kahler-Grand-Hotel.h16119557.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/fc2af524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/6a0aeefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/9472e74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) Kutzky Park 9.4/10 Exceptional (980 reviews) "Room was amazing and the staff was very courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $158 CA $184 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/03b116ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed (Lanai) | Minibar](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/33aa3792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/75ebda11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/6351153f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Austin, MN [](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Austin.h2270.Hotel-Information) Austin 8.2/10 Very good (559 reviews) "Super friendly. Jovial ladies. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn CA $135 CA $150 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Austin.h2270.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/57000000/56950000/56949100/56949056/3051fae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/57000000/56950000/56949100/56949056/d78acdbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/57000000/56950000/56949100/56949056/49e68d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/57000000/56950000/56949100/56949056/a8e72694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Owatonna [](https://www.expedia.ca/Owatonna-Hotels-DoubleTree-By-Hilton-Owatonna.h56949056.Hotel-Information) Owatonna 8.4/10 Very good (21 reviews) "Beautiful facility" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee CA $135 CA $149 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Owatonna-Hotels-DoubleTree-By-Hilton-Owatonna.h56949056.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10530000/10520400/10520324/0ce9e41f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/11000000/10530000/10520400/10520324/06383925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/11000000/10530000/10520400/10520324/2a1c1b2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10530000/10520400/10520324/2980f0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Charmant Hotel [](https://www.expedia.ca/La-Crosse-Hotels-The-Charmant-Hotel.h10520324.Hotel-Information) Historic Downtown La Crosse 9.6/10 Exceptional (1,000 reviews) "Great place!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn CA $186 CA $245 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/La-Crosse-Hotels-The-Charmant-Hotel.h10520324.Hotel-Information) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/90f9b86d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/w4500h3279x0y2-db2e0240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/b65aee43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/06ffc248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Viking Lakes Hotel [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) Eagan 9.6/10 Exceptional (1,005 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee CA $229 CA $254 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-04&endDate=2026-02-05®ionId=6059950&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Top Southern Minnesota Hotel Reviews ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "The amenities and the great customer service. " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Very helpful staff. Wasn't able to try breakfast due to my schedule" [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "Very clean great service." [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "Clean room...helpful staff. Thank you for a great experience. " [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "It is great but very noisy next to active construction. Very hard to rest in between appointments. BRING EAR PLUGS. " [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Clean and nice rooms" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![St James Hotel, a Historic Hotel of America](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "We checked in on Christmas Day 2025 and stayed 1 night. The hotel is in the heart of beautiful downtown Red Wing, MN. The hotel was beautifully decorated for the holidays and was warm and inviting. We had brunch at the beautiful Scarlet Kitchen and Bar and the food and service could not have been better. The restaurant was busy, yet the vibe was elegantly relaxed. Our room was a beautiful union of history in modern times. The beautiful 4-post bed was so comfortable and I need to know where I can get a set of those bed sheets! So buttery soft—best night’s sleep! I will be back St. James Hotel. Highly recommend. Beautiful and quaint shops and dining on-site and within walking distance in Red Wing. Beautiful and historic." [](https://expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg) ### Holiday Inn Express Rochester South - Mayo Area by IHG 10/10 Excellent "Clean room, clean hotel, friendly staff Would stay here again." 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