Best Western Hotels in Southern Minnesota
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A lake surrounded by dense forest and a distant hill with a fort.

Find Hotels by Best Western in Southern Minnesota from CA $141

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Our top choices for Southern Minnesota Best Western

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A modern building with a sign reading "Best Western."

A reception area with a modern design, including a patterned wall, a reception desk, and a sign indicating an event center.

A restaurant setting with round tables, chairs, and empty wine glasses.

1. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property

Rochester

8.2 out of 10, Very good, (1,002 reviews)

8.2/10

Very good

(1,002 reviews)

"clean room, great breakfast and nice we can walk to bar and grill for dinner at night."

jill

The price is CA $142

CA $142

CA $163 total

includes taxes & fees

Nov 22 - Nov 23

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

An indoor swimming pool with multiple levels, lounge chairs, and a staircase.

An outdoor patio with tables, chairs, and umbrellas, surrounded by trees and a building with arches.

A hotel room with a grey sofa, a wooden coffee table, a kitchenette with a microwave, and a bathroom visible through an open door.

A reception area with a flat-screen TV, decorative vases, and coffee dispensers.

2. Best Western Fairmont

Best Western Fairmont

3.0 star property

Fairmont

8.8 out of 10, Excellent, (255 reviews)

8.8/10

Excellent

(255 reviews)

"Nice location"

Harlsnd

The price is CA $189

CA $189

CA $210 total

includes taxes & fees

Nov 22 - Nov 23

Best Western Fairmont

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Top Southern Minnesota Hotel Reviews

A patio area with a round fire pit, outdoor furniture, and a view of a green landscape.

A modern hotel with a sign reading "Towneplace Suites" and a covered outdoor area with seating.

A modern hotel lobby with a grey sofa set, a wooden partition, and a view of a parking lot.

A modern lounge area with seating arrangements, tables, and a decorative wall.

TownePlace Suites by Marriott Mankato

Mankato

10/10 Excellent

Very modern, clean and well maintained. Highly recommend!

Janine

Reviewed June 1, 2026Reviewed June 1, 2026

TownePlace Suites by Marriott Mankato

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A Fairfield Inn & Suites by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

A hotel lobby with a large seating area, a television mounted on the wall, and a coffee station.

A modern lobby with a curved blue sofa, a stone fireplace, and a reception desk with a sign reading "Connect & Print".

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

10/10 Excellent

Nice and clean. Good breakfast. For additional food you have Danny's just around the corner.

Alexey

Reviewed July 24, 2024Reviewed July 24, 2024

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

A modern hotel room with a large window, a sofa set, a dining table, and a lamp.

A modern hotel entrance with a glass facade, a covered entrance area, and a visible 'Hilton' sign.

A spacious lobby with modern furniture, a staircase, and large windows.

Hilton Rochester Mayo Clinic Area

Downtown Rochester

10/10 Excellent

It was brand new and staff were helpful / friendly

Anonymous traveller

Reviewed April 29, 2019Reviewed April 29, 2019

Hilton Rochester Mayo Clinic Area

A large blue sign for the Americinn by Wyndham hotel with a clear sky and a parking lot in front.

An indoor swimming pool with a tiled deck, a lifeguard chair, and a wooden ceiling.

The entrance to AmericInn by Wyndham, featuring a stone facade, a blue sign with stars, and a number 240.

A hotel room with a large bed, two bedside tables with lamps, a wooden door, and three framed pictures on the wall.

AmericInn by Wyndham Mankato Event Center

Mankato

10/10 Excellent

Decent place to stay. Breakfast was good. Close to MSU campus

Neeru

Reviewed August 18, 2026Reviewed August 18, 2026

AmericInn by Wyndham Mankato Event Center

A living room with a brick fireplace, two armchairs with decorative pillows, and a framed map on the wall.

A hotel room with a large bed, a desk, a chair, a desk lamp, a TV, a window with curtains, a wall-mounted TV, a wall-mounted picture, a bedside table, a lamp, and a bathtub.

A lobby with a checkered floor, two blue armchairs, a table with a lamp, and a 'WELCOME' sign.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

Country Trails Inn & Suites

Preston

10/10 Excellent

Very Nice Staff friendly

TERESA

Reviewed July 30, 2025Reviewed July 30, 2025

Country Trails Inn & Suites

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern living room with a grey sectional sofa, a wooden coffee table, and a hanging light fixture.

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

10/10 Excellent

Hotel was very comfortable and was close walk to great restaurants nearby.

Heather

Reviewed July 18, 2024Reviewed July 18, 2024

EVEN Hotel Rochester - Mayo Clinic Area by IHG

A modern dining area with high tables, chairs, and pendant lighting.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A hotel room with a gray sofa, a small dining table, a microwave, a dishwasher, a coffee maker, and a large window with blinds.

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

Hampton Inn & Suites Rochester-North

Rochester

10/10 Excellent

The staff was courteous and flexible.

Anthony

Reviewed September 23, 2026Reviewed September 23, 2026

Hampton Inn & Suites Rochester-North

An outdoor patio area with tables and chairs, stone pillars, and a building labeled "Courtyard."

A Courtyard by Marriott hotel with outdoor seating, a water feature, and a well-maintained garden.

A hotel lobby with a bar area, seating arrangements, and a reception desk.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

Courtyard Mankato Marriott

Mankato

10/10 Excellent

Location to the ball fields for ISC Worlds was ideal with shopping and restaurants nearby

Catherine

Reviewed August 9, 2025Reviewed August 9, 2025

Courtyard Mankato Marriott

A modern hotel with a covered entrance, multiple floors, and a prominent 'Spark by Hilton' sign.

An indoor swimming pool with clear blue water, surrounded by white walls and blue accents, and a tiled floor.

A hotel with a covered entrance, multiple floors, and a parking lot.

Spark by Hilton Rochester South

Rochester

10/10 Excellent

Clean, new hotel within walking distance of restaurants, stores and a theatre.

Kimberly

Reviewed August 16, 2026Reviewed August 16, 2026

Spark by Hilton Rochester South

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Find Hotels by Best Western in Southern Minnesota from CA $141

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southern Minnesota Best Western

1. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2. Best Western Fairmont

Top Southern Minnesota Hotel Reviews

TownePlace Suites by Marriott Mankato

10/10 Excellent

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