A calm lake with a row of canoes on the shore and a single canoe on the water.

Find Hotels by Best Western in Southern Minnesota from CA $149

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Check prices for these dates

Tonight
Aug 21 - Aug 22
Tomorrow
Aug 22 - Aug 23
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Our top choices for Southern Minnesota Best Western

1. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
CA $130
CA $149 total
includes taxes & fees
Aug 27 - Aug 28
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2. Best Western Fairmont

Best Western Fairmont
Fairmont
United States
Kalkidan
CA $177
CA $196 total
includes taxes & fees
Sep 10 - Sep 11
Best Western Fairmont
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Top Southern Minnesota Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good
"I stayed; be night. The front desk was courteous and helpful. The room was affordable and clean. Loved the water pressure in the shower. 😊"
Wendy 1-night trip
Posted 2 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Best Hotel ibe stayed at. Place was clean. Staff was friendly, hot tub was hot which never happens and rooms are very nice"
James 1-night trip
Posted 2 hours ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

8/10 Good
"NA"
Atta Ur Rehman 7-night trip
Posted 3 hours ago
Hyatt House Rochester/Mayo Clinic Area
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"Good breakfast"
Denis 1-night trip
Posted 6 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"You can't beat the Kahler for being close to the Mayo Clinic. The rooms have been remodeled and are generally very clean. Some of the bathroom fixtures are dated, but still functional. For a clean room, nice bed and close to Mayo, it's still my choice when I travel to Rochester."
Bradley 1-night trip
Posted 9 hours ago
Kahler Grand Hotel
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Excellent stay... good breakfast"
Joseph 3-night trip
Posted 21 hours ago
Hampton Inn Rochester-South
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good
"Great location for a visit to Mayo, within walking distance, which I would totally recommend rather than navigating a car in that craziness. The Twigs Bar and Restaurant were delicious and the outdoor patio was lovely."
jeani 2-night trip
Posted 22 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America

10/10 Excellent
"Port bar a must"
Kent 1-night trip
Posted 1 day ago
St James Hotel, a Historic Hotel of America
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

10/10 Excellent
"Nice place to stay!"
Carol 1-night trip
Posted 2 days ago
Express Suites Riverport Inn & Suites

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