Title: The 10 Best Hotels Near Mayo Clinic, Rochester from CA $104 | Expedia.ca [Mayo Clinic Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic.d6126906.Car-Rental-Guide)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic-Downtown-Rochester.d6126906.Vacation-Attraction) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Mayo Clinic, Rochester from CA $104 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6126906&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6126906&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6126906&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6126906&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Mayo Clinic ![Property amenity](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/5817de71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pub](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/ed3fe960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/3007907d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69690000/69681200/69681188/e2269273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Rochester Mayo Clinic Area Downtown Rochester, 0.4 km from Mayo Clinic 9.6/10 Exceptional (462) "Truly a great place to stay! " CA $166 CA $191 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/f4c0d6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/1213b471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area Downtown Rochester, 0.3 km from Mayo Clinic 9.6/10 Exceptional (518) "Great hotel and location. Will definitely select this property again for my next stay in Rochester. " CA $229 CA $264 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/4d028fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/5776b64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/36a69ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkman Folwell, 1.4 km from Mayo Clinic 9.6/10 Exceptional (354) "Excellent staff, great location and reasonable price." CA $128 CA $149 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/9bad372e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/93f8a6ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/39097f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/c8e01189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys Kutzky Park, 1.8 km from Mayo Clinic 9.6/10 Exceptional (664) "Very clean, friendly staff, great breakfast selection" CA $145 CA $167 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park, 1 km from Mayo Clinic 9.4/10 Exceptional (919) "Great stay! Looking forward to coming back next time we’re in the area!" CA $123 CA $144 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/d3d3fd48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/eaf81c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/7ee0db4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 2.6 km from Mayo Clinic 9.6/10 Exceptional (857) "everything was excellent" CA $167 CA $192 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/fe413203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/c5ed6677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/acf22658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/f5e99e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Towers At Kahler Grand Hotel Downtown Rochester, 0.1 km from Mayo Clinic 9.4/10 Exceptional (88) "Concierge was amazing! Breakfast and amazing dinner included with stay. Literally across the street from Mayo and Ruth Chris on the first level." CA $465 CA $536 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Rochester-Hotels-The-Towers-At-Kahler-Grand-Hotel.h16119557.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/2feb2cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/b9f9338b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/2c900d49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59810000/59802900/59802871/0b6104cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Rochester - Mayo Clinic Area by IHG Kutzky Park, 1 km from Mayo Clinic 9.4/10 Exceptional (411) "Breakfast is great, staff is chill, place is clean, comfortable. " CA $174 CA $203 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a8a8ab63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/66e376cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/fa38f94a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/130f3b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Broadway Plaza, Trademark Collection by Wyndham Downtown Rochester, 0.3 km from Mayo Clinic 9.2/10 Wonderful (163) "Great spacious apartments for long stay. " CA $226 CA $261 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26960000/26950400/26950395/18e66eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26960000/26950400/26950395/f2cecef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/27000000/26960000/26950400/26950395/7ef1c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/27000000/26960000/26950400/26950395/0402ae40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Rochester Mayo Clinic Area by IHG 2.6 km from Mayo Clinic 9.4/10 Exceptional (445) "Clean & easy access" CA $142 CA $163 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Rochester-Hotels-Candlewood-Suites-Rochester-Mayo-Clinic-Area.h26950395.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/43e42846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/92f12723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/ad8fe2d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Rochester/Mayo Clinic Area Downtown Rochester, 0.5 km from Mayo Clinic 9.0/10 Wonderful (1014) "Great location, great staff, great room." CA $184 CA $212 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/674459db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch flat-screen TV with premium channels, TV](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/4f8ac266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Accessible, Non Smoking (Roll-in Shower)](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/4974e79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/90603a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys Kutzky Park, 1.4 km from Mayo Clinic 9.2/10 Wonderful (461) "I love staying at Homewood Suites" CA $149 CA $171 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Rochester-Hotels-Homewood-Suites-By-Hilton-Rochester-Mayo-Clinic-Area-Saint-Marys.h9120037.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester, 0.3 km from Mayo Clinic 8.8/10 Excellent (839) "Very convenient to Mayo clinic and good restaurants. " CA $98 CA $113 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/8b35b717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/13abbe0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites 1.2 km from Mayo Clinic 9.0/10 Wonderful (665) "Great stay, breakfast options could use some work but waffle was great. " CA $155 CA $188 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/f77375e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites Downtown Rochester, 0.3 km from Mayo Clinic 8.8/10 Excellent (1002) "Decent room, clean and friendly staff! Great stay!" CA $158 CA $182 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/b39d1efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/74573dc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/8c8d6f87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1270000/1263400/1263391/a82abe94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys Kutzky Park, 1.4 km from Mayo Clinic 9.0/10 Wonderful (748) "The staff was friendly and helpful. The hotel was very clean. " CA $146 CA $168 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Courtyard-By-Marriott-Rochester-Mayo-Clinic-AreaSaint-Marys.h1263391.Hotel-Information) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/67ee8968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/a4f912ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/91d3eb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/3da7831f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Rochester Downtown, MN Downtown Rochester, 0.3 km from Mayo Clinic 8.8/10 Excellent (821) "Wonderful breakfast options and staff." CA $135 CA $156 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area 3 km from Mayo Clinic 9.0/10 Wonderful (835) "Liked our stay!" CA $91 CA $104 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/90393dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/403ba836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/79a3373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4920000/4913700/4913635/a7ddf3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG Kutzky Park, 1.6 km from Mayo Clinic 8.8/10 Excellent (746) "Clean room, pleasant staff, easy parking." CA $150 CA $173 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Express-Suites-Rochester-Mayo-Clinic-Area.h4913635.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/90-7c7f5126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/09aaef0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Rochester-South 2.9 km from Mayo Clinic 9.0/10 Wonderful (1028) "Nice accommodations and great breakfast selection." CA $111 CA $128 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01®ionId=6126906&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Mayo Clinic Hotel Reviews ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Kahler inn & suites is so conveniently close to Mayo. The rooms are clean and comfortable, and breakfast was great!" [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "every thing is go o d" [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Brentwood Inn & Suites](//images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "Decent room, clean and friendly staff! Great stay!" [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "Shower was great! Breakfast was awesome!!" [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Clean room, great options without having to go outside and easy access to parking ramp and skyway" [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hampton Inn Rochester-South](//images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Great place to stay. Awesome some breakfast." [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Aspen Select](//images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 10/10 Excellent "Friendly staff. Nice rooms. Several good restaurants nearby. Convenient access to the hospital." [](https://expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](//images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Good experience overall." [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Hilton Garden Inn Rochester Downtown, MN](//images.trvl-media.com/lodging/1000000/220000/214700/214679/67ee8968_y.jpg) ### Hilton Garden Inn Rochester Downtown, MN 10/10 Excellent "The service was great, especially the shuttle service." [](https://expedia.ca/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ## Hotels near other Mayo Clinic attractions [](https://www.expedia.ca/Soldiers-Field-Veterans-Memorial-Hotels.0-l6212573-0.Travel-Guide-Filter-Hotels) ### Soldiers Field Veterans Memorial 4.5/5 (30 reviews) You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6212573) [](https://www.expedia.ca/Plummer-Building-Hotels.0-l950929261322485760-0.Travel-Guide-Filter-Hotels) ### Plummer Building You can find out about the history of Rochester when you stop by Plummer Building. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950929261322485760) [](https://www.expedia.ca/Shops-University-Square-Hotels.0-l6188938-0.Travel-Guide-Filter-Hotels) ### Shops University Square 4.4/5 (206 reviews) During your visit to Rochester, you can browse for the perfect souvenirs at Shops University Square. You can attend a sporting event while in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6188938) [](https://www.expedia.ca/Rochester-Public-Library-Hotels.0-l940731566819536896-0.Travel-Guide-Filter-Hotels) ### Rochester Public Library Rochester Public Library is just one of the places to see in Rochester, so why not enjoy the other things to explore during your travels? [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=940731566819536896) [](https://www.expedia.ca/Mayo-Civic-Center-Hotels.0-l6126914-0.Travel-Guide-Filter-Hotels) ### Mayo Civic Center 4.5/5 (411 reviews) Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6126914) [](https://www.expedia.ca/Rochester-Civic-Theater-Hotels.0-l6092555-0.Travel-Guide-Filter-Hotels) ### Rochester Civic Theater You can make plans for a show at Rochester Civic Theater during your trip to Rochester. Attend a sporting event or simply visit the area's shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092555) [](https://www.expedia.ca/Rochester-Art-Center-Hotels.0-l6126920-0.Travel-Guide-Filter-Hotels) ### Rochester Art Center You can spend time exploring the galleries in Rochester Art Center in Rochester. Attend a sporting event or simply visit the area's shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6126920) [](https://www.expedia.ca/Mayo-Park-Hotels.0-l697571812817879040-0.Travel-Guide-Filter-Hotels) ### Mayo Park After visiting Mayo Park, make a plan to see the other sights and activities in Rochester. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=697571812817879040) ## Frequently asked questions ### What are the top-rated hotels near Mayo Clinic? > Discovering the top-rated hotels near Mayo Clinic ensures a comfortable and convenient stay during your visit to Rochester, Minnesota. > > > > [Home2 Suites by Hilton Rochester Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) > > > > Home2 Suites by Hilton Rochester Mayo Clinic Area is a welcoming 3-star hotel located just 4.5 km from Mayo Clinic, rated 9.6 by travellers. Guests appreciate the modern amenities, including a kitchenette with a dishwasher and microwave, as well as a cozy sofa bed. The hotel features complimentary daily breakfast and an accessible indoor pool, making it a perfect choice for those seeking a relaxed atmosphere. With additional perks like Egyptian cotton sheets and a fitness centre, this hotel ensures comfort and convenience for every traveler. > > > > [Residence Inn by Marriott Rochester Mayo Clinic Area South](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) > > > > Residence Inn by Marriott Rochester Mayo Clinic Area South is another excellent option, situated 4.5 km from Mayo Clinic and a review rating of 9.6. This 3-star hotel offers spacious rooms with full kitchens and a convenient wet bar, ideal for longer stays. Guests can enjoy a complimentary breakfast and take advantage of the indoor pool and hot tub. The fitness centre is accessible 24 hours, ensuring travellers can maintain their routine while away from home. > > > > [Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information) > > > > Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is perfectly located just 2.4 km from Mayo Clinic, earning an impressive review rating of 9.6. This hotel features comfortable suites and an inviting atmosphere, complete with an indoor pool and a rooftop garden for relaxation. Guests can enjoy complimentary breakfast and easy access to an onsite tennis court, making it a great choice for those looking to stay active during their visit. ### What hotels are within walking distance to Mayo Clinic? > Discover the convenience of top-rated hotels within walking distance to Mayo Clinic, perfect for travellers seeking comfort and accessibility. > > > > [Hilton Rochester Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) > > > > Hilton Rochester Mayo Clinic Area is a welcoming 3.5-star hotel located just a 6-minute walk from Mayo Clinic, with an impressive review rating of 9.6. This hotel features an indoor pool, a full-service spa offering massages and aromatherapy treatments, and a fitness centre open 24 hours. Guests can also enjoy relaxing moments in the hot tub and steam room, making it an excellent choice for relaxation after a day at the clinic. > > > > [TownePlace Suites by Marriott Rochester Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-TownePlace-Suites-By-Marriott-Rochester-Mayo-Clinic-Area.h69681188.Hotel-Information) > > > > TownePlace Suites by Marriott Rochester Mayo Clinic Area is a cozy 3-star hotel that is only a 5-minute stroll from Mayo Clinic, rated 9.6 by travellers. It offers a complimentary buffet breakfast and 24-hour fitness facilities. Guests appreciate the rooftop garden and the convenience of in-room kitchens, perfect for those looking to prepare their own meals. The hotel also provides free area shuttle services, adding to its overall convenience for travellers. > > > > [Staybridge Suites Rochester - Mayo Clinic Area by IHG](https://www.expedia.ca/Rochester-Hotels-Staybridge-Suites-Rochester-St-Marys-Area.h59802871.Hotel-Information) > > > > Staybridge Suites Rochester - Mayo Clinic Area by IHG is a comfortable 3-star hotel located a 12-minute walk from Mayo Clinic, with a solid review rating of 9.4. This hotel features an indoor pool and a hot tub, along with spacious suites equipped with kitchens and premium bedding. Guests can enjoy a complimentary breakfast daily and take advantage of the free area shuttle service, making it an ideal base for those visiting the clinic. ### How much is a hotel near Mayo Clinic? > Staying near Mayo Clinic is a treat, with plenty of hotels from CA $104 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays. ### What are the most popular family-friendly hotels near Mayo Clinic? > For families visiting Mayo Clinic, finding the perfect family-friendly hotel is essential for a comfortable stay. Here are some of the top-rated options that cater to families. > > > > [Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) > > > > Located just an 8-minute walk from Mayo Clinic, the Centerstone Plaza Hotel Soldiers Field is a family-friendly haven with a review rating of 8.4 and a 3-star rating. This hotel features an indoor pool with a children's area, free daily breakfast, and kitchens in select rooms, perfect for families. Guests will appreciate the comfortable accommodations and easy access to the clinic. > > > > [Med City Inn & Suites - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) > > > > Med City Inn & Suites offers an inviting atmosphere just 2.1 km from Mayo Clinic, perfect for families. With a great traveler rating score of 8.0, this hotel features a fantastic waterslide and a children's pool to keep the little ones entertained. Guests can also enjoy complimentary breakfast, a kitchenette in the rooms, and a game room designed for family fun, ensuring a memorable stay. > > > > [Kahler Grand Hotel](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) > > > > Just a 3-minute walk from Mayo Clinic, Kahler Grand Hotel is an ideal family-friendly choice with a review rating of 8.2 and a 3-star rating. Families will enjoy amenities like free cribs, connecting rooms, and a children's menu at the on-site restaurant. With its indoor pool and convenient location, travellers can easily balance relaxation and access to the clinic. ### What are the best affordable hotels near Mayo Clinic? > Finding a budget-friendly hotel near Mayo Clinic can enhance your stay and provide peace of mind during your visit. Here are some top-rated options that offer great amenities without breaking the bank. > > > > [Home2 Suites by Hilton Rochester Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) > > > > Home2 Suites by Hilton Rochester Mayo Clinic Area is a 3-star hotel located just 4.5 km from Mayo Clinic, with an impressive review rating of 9.6. This family-friendly hotel features complimentary breakfast daily, including a buffet on weekends, and offers a variety of amenities such as a fitness centre, free WiFi, and a kitchenette in each suite. Guests can also enjoy the convenience of free area shuttle service and on-site grocery shopping service. > > > > [Residence Inn by Marriott Rochester Mayo Clinic Area South](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) > > > > Residence Inn by Marriott Rochester Mayo Clinic Area South is another excellent 3-star option, situated 4.5 km from Mayo Clinic with a stellar review rating of 9.6. Ideal for families, this hotel features a complimentary continental breakfast and an indoor pool perfect for relaxation. Guests will appreciate the fully equipped kitchens in the suites, free WiFi, and accessible fitness facilities to maintain their routine while traveling. > > > > [Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys](https://www.expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information) > > > > Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys stands out with a prime location just 2.4 km from Mayo Clinic and a popular review rating of 9.6. This family-friendly hotel offers free breakfast options and access to an indoor pool, making it a great choice for leisure and relaxation. Additional amenities include free parking, WiFi, and a fitness centre, ensuring travellers have all they need for a comfortable stay. ### Are there any hotels with pools close to Mayo Clinic? > If you're looking for hotels with pools near Mayo Clinic, Rochester offers some great options that cater to travellers seeking relaxation and comfort during their stay. > > > > [Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) > > > > Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area is located only 8 minutes from Mayo Clinic and has an excellent review rating of 8.4. This hotel offers an indoor pool with features for children and accessibility options. Guests can also take advantage of free buffet breakfast, 24-hour fitness facilities, and easy access to nearby golf courses and historical sites. > > > > [Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) > > > > Best Western Rochester Hotel Mayo Clinic Area/St. Mary's is conveniently located just 3.5 km from Mayo Clinic, making it an ideal choice for travellers. With an impressive review rating of 8.2, this hotel features an indoor pool complete with a waterslide and children's area—perfect for families. Guests can also enjoy free breakfast, a hot tub, and easy access to local golf courses. > > > > [Kahler Inn and Suites - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) > > > > Kahler Inn and Suites - Mayo Clinic Area is just a 3-minute walk from Mayo Clinic and boasts a great traveler rating score of 7.8. This family-friendly hotel features an indoor pool with accessibility options, making it suitable for everyone. Guests can enjoy amenities like a kitchenette in the rooms, free breakfast, and covered parking, ensuring a comfortable stay. ### What are the best pet-friendly hotels near Mayo Clinic? > For travellers seeking pet-friendly accommodations near the Mayo Clinic, these top-rated hotels offer welcoming stays for both you and your furry friend. > > > > [Residence Inn by Marriott Rochester Mayo Clinic Area South](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) > > > > Residence Inn by Marriott stands out with an impressive 9.6 travellers' rating and is located 4.5 km from the Mayo Clinic. This 3-star hotel allows both dogs and cats, making it a perfect choice for travellers with pets. Guests will appreciate the complimentary breakfast, an indoor pool, and a fitness centre. Additional features include a fully equipped kitchen in every suite and convenient parking options. > > > > [Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) > > > > Centerstone Plaza Hotel Soldiers Field is just an 8-minute walk from the Mayo Clinic and has a welcoming atmosphere for pets, earning a review rating of 8.4. This 3-star hotel features an indoor pool, free buffet breakfast, and a fitness centre. Guests can also enjoy nearby golf, a terrace, and family-friendly amenities such as cribs and kid-friendly meals. > > > > [Med City Inn & Suites - Mayo Clinic Area](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) > > > > Med City Inn & Suites is a cozy and inviting option just 2.1 km from the Mayo Clinic, with a solid review rating of 8.0. This pet-friendly hotel welcomes dogs and offers essential amenities like free breakfast, an indoor pool, and a hot tub, ensuring a comfortable stay. Guests can also enjoy a fitness centre, kitchenette options, and complimentary toiletries. ### Can I book a fully refundable hotel close to Mayo Clinic? > Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mayo Clinic", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore [deals with free cancellation](https://www.expedia.ca/deals/free-cancellation) options on Expedia. ### Can I find Expedia discounts for hotels near Mayo Clinic? > Sign in to your account to unlock instant savings and access Member Prices on Expedia. 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