Title: Car Rental Mayo Clinic, MN - Expedia.ca [Downtown Rochester Travel Guide](https://expedia.ca/Rochester-Downtown-Rochester.dx553248635976481217)[Mayo Clinic Hotels](https://expedia.ca/Mayo-Clinic-Hotels.0-l6126906-0.Travel-Guide-Filter-Hotels)[Mayo Clinic Vacations](https://expedia.ca/Mayo-Clinic-Downtown-Rochester.d6126906.Vacation-Attraction) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Mayo Clinic Car Rental ## Search and Compare from Car Companies in Mayo Clinic ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in Mayo Clinic \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Rochester, Minnesota, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo%20Clinic,%20Rochester,%20Minnesota,%20United%20States%20of%20America&dpln=6126906&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Rochester, Minnesota, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo%20Clinic,%20Rochester,%20Minnesota,%20United%20States%20of%20America&dpln=6126906&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Rochester, Minnesota, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo%20Clinic,%20Rochester,%20Minnesota,%20United%20States%20of%20America&dpln=6126906&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Rochester, Minnesota, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo%20Clinic,%20Rochester,%20Minnesota,%20United%20States%20of%20America&dpln=6126906&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Mayo Clinic [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo%20Clinic,%20Rochester,%20Minnesota,%20United%20States%20of%20America&dpln=6126906&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### Can I rent a car near Mayo Clinic? ### How much is car rental near Mayo Clinic? ### Which car rental companies have a drop off near Mayo Clinic? ### How much is parking near Mayo Clinic? ### Are there electric car charging stations near Mayo Clinic? ### What is the closest airport to Mayo Clinic? ### Where is Mayo Clinic in Rochester? ### What else is there to do near Mayo Clinic? ### What time does Mayo Clinic open and close? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - 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