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Our top choices for St. Charles hotels

Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo ClinicRochester
8.8 out of 10, Excellent, (1,003 reviews)
The price is CA $90
CA $104 total
includes taxes & fees
May 17 - May 18

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.4 out of 10, Good, (1,058 reviews)
The price is CA $100
CA $115 total
includes taxes & fees
May 11 - May 12

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaHistoric Southwest
8.6 out of 10, Excellent, (1,009 reviews)
The price is CA $156
CA $180 total
includes taxes & fees
Jun 3 - Jun 4

Super 8 by Wyndham Winona MN
Super 8 by Wyndham Winona MNWinona
7.8 out of 10, Good, (1,010 reviews)
The price is CA $83
CA $95 total
includes taxes & fees
May 13 - May 14

Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-NorthRochester
9.2 out of 10, Wonderful, (1,004 reviews)
The price is CA $156
CA $179 total
includes taxes & fees
May 17 - May 18

AmericInn by Wyndham Winona
AmericInn by Wyndham WinonaWinona
9.0 out of 10, Wonderful, (932 reviews)
The price is CA $162
CA $180 total
includes taxes & fees
Jun 7 - Jun 8

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo ClinicRochester
8.0 out of 10, Very good, (1,009 reviews)
The price is CA $91
CA $104 total
includes taxes & fees
May 11 - May 12

Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic AreaDowntown Rochester
8.0 out of 10, Very good, (1,580 reviews)
The price is CA $178
CA $205 total
includes taxes & fees
May 10 - May 11

MainStay Suites Rochester South Mayo Clinic
MainStay Suites Rochester South Mayo ClinicRochester
7.0 out of 10, Good, (109 reviews)
The price is CA $81
CA $93 total
includes taxes & fees
May 17 - May 18

Extended Stay America Suites Rochester North
Extended Stay America Suites Rochester NorthRochester
7.6 out of 10, Good, (701 reviews)
The price is CA $85
CA $98 total
includes taxes & fees
May 27 - May 28

Express Suites Riverport Inn & Suites
Express Suites Riverport Inn & SuitesWinona
8.6 out of 10, Excellent, (1,005 reviews)
The price is CA $148
CA $165 total
includes taxes & fees
May 27 - May 28

Days Inn by Wyndham Winona
Days Inn by Wyndham WinonaWinona
7.8 out of 10, Good, (1,001 reviews)
The price is CA $92
CA $103 total
includes taxes & fees
May 10 - May 11

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sRochester
8.2 out of 10, Very good, (909 reviews)
The price is CA $129
CA $148 total
includes taxes & fees
May 24 - May 25

Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med CityRochester
7.0 out of 10, Good, (36 reviews)
The price is CA $88
CA $101 total
includes taxes & fees
May 10 - May 11

Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,007 reviews)
The price is CA $123
CA $142 total
includes taxes & fees
Jun 6 - Jun 7

Quality Inn near Medical Center
Quality Inn near Medical CenterRochester
7.8 out of 10, Good, (880 reviews)
The price is CA $86
CA $99 total
includes taxes & fees
Jun 1 - Jun 2

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,006 reviews)
The price is CA $126
CA $145 total
includes taxes & fees
May 24 - May 25

AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.2 out of 10, Very good, (1,312 reviews)
The price is CA $105
CA $121 total
includes taxes & fees
May 31 - Jun 1

Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.4 out of 10, Exceptional, (465 reviews)
The price is CA $105
CA $121 total
includes taxes & fees
Jun 7 - Jun 8

Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic AreaKutzky Park
7.8 out of 10, Good, (1,015 reviews)
The price is CA $100
CA $115 total
includes taxes & fees
May 20 - May 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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St. Charles awaits: its natural setting and more!

Top St. Charles Hotel Reviews
Recent Reviews in St. Charles

Hotel Indigo Rochester – Mayo Clinic Area by IHG
6/10 Okay
More cheap stays in St. Charles

Super 8 by Wyndham Winona MN
1025 Sugar Loaf Rd Winona MN
The price is CA $83 per night from May 13 to May 14
CA $83
CA $95 total
May 13 - May 14
includes taxes & fees
7.8/10 Good! (1,010 reviews)
Hotels in St. Charles with star rating

4 Star Hotels
2 properties
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