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Our top choices for St. Charles hotels

1. Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.2 out of 10, Wonderful, (605 reviews)
The price is CA $94
CA $108 total
includes taxes & fees
Nov 22 - Nov 23

2. Stone Mill Hotel & Suites
Stone Mill Hotel & SuitesLanesboro
9.6 out of 10, Exceptional, (730 reviews)
The price is CA $147
CA $158 total
includes taxes & fees
Dec 6 - Dec 7

3. Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $120
CA $138 total
includes taxes & fees
Nov 14 - Nov 15

4. Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (1,005 reviews)
The price is CA $96
CA $111 total
includes taxes & fees
Dec 4 - Dec 5

5. Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo ClinicRochester
8.8 out of 10, Excellent, (1,006 reviews)
The price is CA $107
CA $123 total
includes taxes & fees
Dec 6 - Dec 7

6. Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic AreaRochester
8.8 out of 10, Excellent, (971 reviews)
The price is CA $93
CA $108 total
includes taxes & fees
Nov 28 - Nov 29

7. The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor WennesonPeterson
9.6 out of 10, Exceptional, (101 reviews)
The price is CA $146
CA $160 total
includes taxes & fees
Nov 11 - Nov 12

8. Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
The price is CA $156
CA $179 total
includes taxes & fees
Nov 27 - Nov 28

9. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.6 out of 10, Good, (1,059 reviews)
The price is CA $100
CA $115 total
includes taxes & fees
Nov 15 - Nov 16

10. AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.2 out of 10, Very good, (1,599 reviews)
The price is CA $102
CA $117 total
includes taxes & fees
Dec 7 - Dec 8

11. Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical CenterRochester
8.8 out of 10, Excellent, (668 reviews)
The price is CA $113
CA $130 total
includes taxes & fees
Nov 28 - Nov 29

12. Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical CenterRochester
9.0 out of 10, Wonderful, (725 reviews)
The price is CA $107
CA $123 total
includes taxes & fees
Nov 28 - Nov 29

13. Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHGDowntown Rochester
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $144
CA $166 total
includes taxes & fees
Nov 14 - Nov 15

14. Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,000 reviews)
The price is CA $137
CA $157 total
includes taxes & fees
Nov 29 - Nov 30

15. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaHistoric Southwest
8.6 out of 10, Excellent, (1,004 reviews)
The price is CA $160
CA $184 total
includes taxes & fees
Nov 7 - Nov 8

16. Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic AreaRochester
7.8 out of 10, Good, (1,000 reviews)
The price is CA $71
CA $82 total
includes taxes & fees
Nov 29 - Nov 30

17. Country Trails Inn & Suites
Country Trails Inn & SuitesPreston
9.4 out of 10, Exceptional, (163 reviews)
The price is CA $177
CA $195 total
includes taxes & fees
Dec 6 - Dec 7

18. Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic AreaKutzky Park
7.8 out of 10, Good, (1,052 reviews)
The price is CA $99
CA $114 total
includes taxes & fees
Dec 7 - Dec 8

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHGKutzky Park
8.6 out of 10, Excellent, (849 reviews)
The price is CA $142
CA $163 total
includes taxes & fees
Nov 14 - Nov 15

20. EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHGKutzky Park
9.4 out of 10, Exceptional, (1,012 reviews)
The price is CA $154
CA $196 total
includes taxes & fees
Nov 27 - Nov 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in St. Charles
![]() Spark by Hilton Rochester SouthRochester | ![]() Stone Mill Hotel & SuitesLanesboro | ![]() Holiday Inn Express Rochester South - Mayo Area by IHGRochester | ![]() Econo Lodge Mayo Clinic AreaRochester | ![]() Comfort Inn & Suites Rochester South Mayo ClinicRochester |
|---|---|---|---|---|
9.2 Wonderful 605 reviews | 9.6 Exceptional 730 reviews | 8.8 Excellent 1,000 reviews | 9.0 Wonderful 1,005 reviews | 8.8 Excellent 1,006 reviews |
The price is CA $94 CA $108 total includes taxes & fees Nov 22 - Nov 23 | The price is CA $147 CA $158 total includes taxes & fees Dec 6 - Dec 7 | The price is CA $120 CA $138 total includes taxes & fees Nov 14 - Nov 15 | The price is CA $96 CA $111 total includes taxes & fees Dec 4 - Dec 5 | The price is CA $107 CA $123 total includes taxes & fees Dec 6 - Dec 7 |
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Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
























































































