Name: Hyatt House Rochester/Mayo Clinic Area
Price range: CA $191
Rating: 9

Photo by Chad Johnson

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Your Rochester Vacation

From its highlights to its hidden gems, this city is best explored with a Rochester vacation package. Check out hotels located in Downtown Rochester, which is great for bars and pubs, history and culture. Make your trip to Rochester even more fun and exciting by going sightseeing. Mayo Civic Center, Apache Mall and National Volleyball Center are among the most popular attractions you'll want to explore. Stop daydreaming and start doing. Check out the many options on Expedia today and finally put your Rochester vacation plans into gear!

Where to stay in Rochester

Find the best Rochester areas and neighborhoods for the activities you enjoy most. Learn more about Rochester

Downtown Rochester

3 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Ready to book your vacation to Rochester?

Choose your dates

Rochester Hotel Deals

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

Fully refundableReserve now, pay when you stay

CA $172

per night

May 22 - May 23

8.4/10 Very Good! (2,098 reviews)

"The best part of our stay was the staff. Everyone was friendly and helpful. Parking was rough. The garage next to the hotel was full and I did not want to pay $34 for valet parking. The next nearest garage was a couple blocks away. With all the construction, the hotel has provided great unloading ..."

Reviewed on May 20, 2026

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw Rochester MN

Fully refundableReserve now, pay when you stay

CA $179

per night

May 22 - May 23

8/10 Very Good! (1,565 reviews)

"Room was clean, the breakfast was very good, only thing we didn't like was the underground parking."

Reviewed on May 20, 2026

Hyatt House Rochester/Mayo Clinic Area

110 Civic Center Drive NW Rochester MN

Fully refundableReserve now, pay when you stay

CA $191

per night

May 31 - Jun 1

9/10 Wonderful! (1,000 reviews)

"breakfast was amazing and the soup of the day was great"

Reviewed on May 19, 2026

See all 437 properties in Rochester

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.