Title: Book the Best BUSINESS Hotels in Southern Minnesota in 2026 | Expedia.ca [Southern Minnesota Travel Guide](https://expedia.ca/Southern-Minnesota.dx6059950)[Hotels in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[Vacation Rentals in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Vacation-Rentals.d6059950.Travel-Guide-VacationRentals)[Flights to Southern Minnesota](https://expedia.ca/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Minnesota.d6059950.Car-Rental-Guide)[Southern Minnesota Vacation Packages](https://expedia.ca/Southern-Minnesota.d6059950.Destination-Travel-Guides) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Minnesota Business Hotels Tonight [Mar 14 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-03-14&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Mar 15 - Mar 16](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-03-15&endDate=2026-03-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southern Minnesota business-friendly hotels ![Indoor pool, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/c875c14c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/21f7d30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffalo Tower Non-Smoking King Accessible](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/59f5dda6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/105000000/104470000/104463200/104463121/4e79af59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Treasure Island Resort & Casino [](https://www.expedia.ca/Welch-Hotels-Treasure-Island-Resort-And-Casino.h104463121.Hotel-Information) Welch 8.2/10 Very good (114 reviews) "Clean room, comfortable bed, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $110 CA $138 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Welch-Hotels-Treasure-Island-Resort-And-Casino.h104463121.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/580300/580253/d4d131dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/590000/580300/580253/17decd77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/590000/580300/580253/0bed0563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/590000/580300/580253/3c002bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Albert Lea at Trails Travel Center [](https://www.expedia.ca/Owatonna-Hotels-Comfort-Inn-Albert-Lea.h580253.Hotel-Information) Albert Lea 8.6/10 Excellent (540 reviews) "Great stay. Nice breakfast, hot tub, pool, room, and staff. Amy was very hospitable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Will CA $116 CA $132 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Owatonna-Hotels-Comfort-Inn-Albert-Lea.h580253.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e0e6ae12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/3fb15b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e13e365d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite) | Living area](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/80518cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Mill Hotel & Suites [](https://www.expedia.ca/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) Lanesboro 9.2/10 Wonderful (669 reviews) "Heather at the front desk gave terrific customer service Her knowledge of the town and places to eat made our stay that much more enjoyable. The owner Ann has done a wonderful job in running the hotel. Her friendliness and out going personality is top notch! Kudos to both of you ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $143 CA $154 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/036a88bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/80a0577c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/c9303a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/0ef4d851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Jackson [](https://www.expedia.ca/Worthington-Hotels-AmericInn-By-Wyndham-Jackson.h1245223.Hotel-Information) Jackson 8.4/10 Very good (440 reviews) "Clean, breakfast at Pennys excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randel CA $135 CA $150 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Worthington-Hotels-AmericInn-By-Wyndham-Jackson.h1245223.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22500/22473/d4d523ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22500/22473/18bb9f70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22473/92059b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22473/ca7a8e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus New Ulm [](https://www.expedia.ca/Mankato-Hotels-Best-Western-Plus-New-Ulm.h22473.Hotel-Information) New Ulm 8.6/10 Excellent (698 reviews) "We always enjoy our stay here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trish CA $153 CA $169 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Mankato-Hotels-Best-Western-Plus-New-Ulm.h22473.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/7134cbc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/b75bfa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/ad31d44c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/fbd34e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Albert Lea - Austin [](https://www.expedia.ca/Owatonna-Hotels-Country-Inn-Suites-By-Radisson.h538443.Hotel-Information) Albert Lea 8.8/10 Excellent (1,000 reviews) "Nice staff, good breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $115 CA $127 total includes taxes & fees Apr 14 - Apr 15 [](https://www.expedia.ca/Owatonna-Hotels-Country-Inn-Suites-By-Radisson.h538443.Hotel-Information) ![Indoor pool, a heated pool, open 6:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/7300/7291/c72d412e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7300/7291/1ea8aa7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/7300/7291/d9ac7848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/10000/7300/7291/51fba05a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Albert Lea [](https://www.expedia.ca/Owatonna-Hotels-Ramada-By-Wyndham-Albert-Lea.h7291.Hotel-Information) Albert Lea 7.2/10 Good (1,000 reviews) "Clean but.could use some attention " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $95 CA $105 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Owatonna-Hotels-Ramada-By-Wyndham-Albert-Lea.h7291.Hotel-Information) ![Suite, Accessible](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/0b6238a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/48e401fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/705a332b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/bc20b74a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites and Conference Center [](https://www.expedia.ca/Worthington-Hotels-Comfort-Suites-And-Conference-Center.h5991960.Hotel-Information) Worthington 9.0/10 Wonderful (476 reviews) "Very nice hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy CA $156 CA $173 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Worthington-Hotels-Comfort-Suites-And-Conference-Center.h5991960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/03a3b0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/50cfb9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/b87a239e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/78f67452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Marshall - University Area [](https://www.expedia.ca/Marshall-Hotels-Sleep-Inn-Suites-Marshall.h7332128.Hotel-Information) Marshall 9.0/10 Wonderful (475 reviews) "Gym was great, but had only one treadmill. Loved having a printed copy of my stay receipt slid under my door in the morning! Will stay here every-time I’m in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasper CA $133 CA $148 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Marshall-Hotels-Sleep-Inn-Suites-Marshall.h7332128.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/27999aed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/567d427e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/5ed80466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856300/856203/c30d1af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites Spring Valley [](https://www.expedia.ca/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) Spring Valley 8.2/10 Very good (441 reviews) "Attentive staff, clean room, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindy CA $116 CA $128 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Rochester-Hotels-Americas-Best-Value-Inn-Suites-Spring-Valley.h856203.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-28&endDate=2026-03-29®ionId=6059950&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AFFINITY_SPRING_PROMO_6059950) ## Top Southern Minnesota Hotel Reviews ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Quick check in, nice room. Insulation is lacking so be prepared to hear your neighbors. Breakfast has a lot of high carb options, so if you’re looking for a protein breakfast, you’ll likely need to eat offsite. " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/edb11216_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "While the room was adequate and cleaner than expected given the age the mattresses had seen better times and were a bit rough but still serviceable. The kitchen appliances while somewhat dated also very clean and worked well. Only downside was the pots and pans to cook with were a little rough. I suggest bring your favorites if you plan on cooking. The restaurant on site was really good and will even bring to your room. Arcade isn’t great so don’t expect the newest but air hockey is solid as is PAC man. Pool was nice our daughter liked it well enough. Didn’t try it out the hot tub out myself but everything was very clean. Another big plus here is the shuttle to hospital. The only real negative we had was the fiasco with billing while they were switching to a new credit card service. The hotel management was quick to help fix and assured us it wouldn’t happen again. It did but was fixed again just took time. " [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 4/10 Poor "The entire property smelled strongly of chlorine from the pool. That included in our room. My friend had irritated eyes and sinuses from it. I had a bad headache. It's a nice property with a great staff, but something needs to be done about the smell. " [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent " Very clean, nice breakfast and convenient to the clinic via walking subway. " [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/404886d5_y.jpg) ### Aspen Suites 10/10 Excellent "Great amenities" [](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg) ### Kahler Grand Hotel 6/10 Okay "For the price parking should be cheaper and breakfast should be free, especially since most people are staying here for medical reasons" [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e_y.jpg) ### Brentwood Inn & Suites 8/10 Good "Pillows were too flat. Only had 3 small pillows 4 would have been nice " [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Good place to stay " [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Rooms were clean, plenty of tasty breakfast options, staff members were very nice, pool and hot tub area were clean and warm." [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Southern Minnesota cost? ### What are the best business-friendly hotels in Southern Minnesota? ### How many business-friendly hotels are there in Southern Minnesota? ### What are the best cheap business-friendly hotels in Southern Minnesota? ### What are the top business-friendly motels in Southern Minnesota? ### Are there any family-friendly hotels in Southern Minnesota that are also business friendly? ### Are there any 5-star business-friendly hotels in Southern Minnesota? ### Why book your business-friendly hotel in Southern Minnesota with Expedia? ### How can I find cheap business-friendly hotels in Southern Minnesota? ### What is there to do in Southern Minnesota near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Springfield ](https://www.expedia.ca/5Star-Springfield-Hotels.s50-0-d6046558.Travel-Guide-Filter-Hotels) - 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