Title: Book the Best HISTORIC Hotels in Sikeston in 2025 | Expedia.ca [Hotels in Sikeston](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman # Find Historic Hotels in Sikeston, MO from CA $257 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sikeston Historic Hotels Tonight [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sikeston Historic Hotels ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/c59bcf0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (142) "Beautiful house. Great stay. Would definitely stay again!" CA $209 CA $342 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/52e075c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/46dd8c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/f5ad31e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/d1990eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Weber Farm - Enjoy a beautiful 100 acre farm! Frohna 10/10 Exceptional (31) "Hosts were great. I just wish they had a second bath or atleast a larger bathroom. " CA $157 CA $257 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h42533836.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/d22aee4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/6b2b149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/4a0f272b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/ded6701c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rest, Relax and Renew. Our log cabin experience awaits your arrival. Anna 10/10 Exceptional (396) "Clean comfortable cabin in a beautiful relaxing setting. Would definitely stay again." CA $163 CA $277 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anna-Hotels-Rest.h31189922.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/3f7db1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/c221a56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/30627e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cottage overlooking Lake Acre Dongola 10/10 Exceptional (99) "So Clean, Comfy and Serene!! Worth the drive for solitude." CA $220 CA $430 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/20000000/19790000/19785200/19785140/0ef68f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/20000000/19790000/19785200/19785140/ab72f577.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19790000/19785200/19785140/66e5e990.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19790000/19785200/19785140/b3b55c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded Cabin. Art. Fast WiFi. Fireplace. New Kitchen Pomona 10/10 Exceptional (91) "Our family decided on a simpler, closer to home vacation this year and this was the perfect spot! We live only about 4 hours away, but felt transported into another place because of the location. It was a wonderful time and we plan to visit again!" CA $252 CA $521 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Pomona-Hotels-Art-Fast-Wifi-Fire-Pit-New-Kitchen-Secluded.h19785140.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19670000/19663200/19663190/610174de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/20000000/19670000/19663200/19663190/aa5bc9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19670000/19663200/19663190/28dd4b91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/20000000/19670000/19663200/19663190/32e9f400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower Alto Pass 9.8/10 Exceptional (174) "We wanted a good central location for our time in wine country. This place was perfect…and we were able to check out several Wineries during our stay. " CA $347 CA $439 total includes taxes & fees Oct 10 - Oct 11 [](https://www.expedia.ca/Carbondale-Hotels-Walk-To-Wineries-Quaint-Village-Grill-Patio-Wifi-Amazing-Shower.h19663190.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=6058766&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Sikeston Hotel Reviews ## Frequently asked questions ### What can a history buff expect from a stay in Sikeston? > Significant historical sites in Sikeston are probably a big part of your travel plans. The array of shops and top-notch restaurants are some of the places to visit while you're here. You can also take some time enjoying the riverfront in this family-friendly area. ### How many historical hotels are located in Sikeston? > In Sikeston, you'll find 15 hotels and other accommodations bookable on Expedia but not many designated as historic hotels. ### What are the most important historical places and other sights to visit in Sikeston? > Sikeston is notable for landmarks like Sikeston Depot Museum. Additionally, you might want to add Central Park to your agenda. ### What is a historic hotel like in Sikeston? > Guests who choose historic hotels have a chance to stay in a building recognized with a national historic designation. Historic hotels throughout the world have had many former lives and uses, such as castles, stately homes, palaces or even pubs, lodges, old police stations or skyscrapers. These types of hotels in Sikeston often preserve original characteristics such as period features or traditional architecture in their communal spaces or guestrooms. ### What is the difference between a historic hotel and a heritage hotel? > The two are similar. "Historic hotel" is a term often used in the U.S., while "heritage hotel" is often used in Asia and Europe. Historic hotels tend to place more significance on the architecture and building. A heritage hotel draws meaning mainly from the cultural value and how it influenced the community. ### Do historic hotels in Sikeston have modern facilities? > Hotels have the safety features and modern conveniences you might expect, though efforts have been made to preserve the historic aspects and traditions. Private rooms with updated bathroom facilities, heating and air conditioning, free and fast Internet, and the normal amenities found in any hotel will also be available in a historic hotel. When you choose a historic hotel in Sikeston, don't worry that you'll be staying at a place that's uncomfortable for guests or simply rundown. ## Explore a world of travel with Expedia - Lodging - Flights - Cars - More ways to book - [B&B in Advance](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [Advance Hotels](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Lodges in Advance](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - 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