Title: Best Sikeston Apart hotels from CA $89 | Expedia.ca [Hotels in Sikeston](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman # Search Apart Hotels in Sikeston ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=APART_HOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Sikeston Aparthotels We don't have any properties that match your exact search [See all properties in Sikeston](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6058766&adults=2) ## Recommended hotels in Sikeston ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1001) "Very nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charity CA $131 CA $148 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1003) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather CA $98 CA $110 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1009) "This was a wonderful stay. We will definitely stay again when we are in town!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trista CA $125 CA $133 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (643) "Stayed on our way south for vacation. It was a clean nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel CA $117 CA $127 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (132) "Excellent hotel…" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danny CA $123 CA $138 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (415) "Clean room, nice staff. Would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robbin CA $136 CA $154 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (700) "Stayed one night. Good rate for the Hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $78 CA $89 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1003) "Everything nice clean and friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $125 CA $142 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (434) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen CA $141 CA $159 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (457) "The Staff was friendly The restaurant was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sirron CA $162 CA $183 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/4de18ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/e322869e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG Cape Girardeau 8.2/10 Very good (860) "Great staff and convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg CA $105 CA $126 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1004) "Always enjoy our stay. Staff is very friendly, especially at breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $98 CA $110 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1001) "Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $131 CA $151 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8df39481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1001) "Wonderful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carrie CA $107 CA $123 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview Cape Girardeau 9.4/10 Exceptional (442) "Location was perfect for family weekend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $126 CA $143 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/cfaba55a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (763) "The property staff were lovely and the hotel was clean and renovated!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $136 CA $154 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1015) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine CA $117 CA $134 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.2/10 Wonderful (28) "Very clean and comfortable room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roxanne CA $141 CA $159 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1001) "It was right off the interstate with lots of restaurant options " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $138 CA $156 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (83) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $125 CA $142 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6058766&adults=2&lodging=APART_HOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Apart-Hotels.d6058766-aaApartHotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Apart-Hotels.d6058766-aaApartHotels.Travel-Guide-Accommodation) ## Top Sikeston Hotel Reviews ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Great service " [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Everything was up to par. Enjoyed our stay. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "It was a nice stay" [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Enjoyed the evening meal. Children enjoyed the hotdogs and nachos. Everything was great!" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The beds were so comfortable!" [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great stay" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "okay" [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Best Western Plus Sikeston](//images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "All good here" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](//images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "The room was clean and the property was well maintained. The breakfast had a waffle maker as well as bagels and pastry. Too bad they don't provide liquid coffee creamer instead of powder. It was a decent stay for the price." [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ## Find out more about Sikeston ## Sikeston Aparthotels information | Number of reviews | 13,984 | | --- | --- | | Accommodation | 1 Aparthotels | | Lowest Price | CA $89 | | Highest Price | CA $183 | ## Frequently asked questions ### What should I expect during my aparthotel stay in Sikeston? > You'll likely stay centrally in Sikeston when you choose an aparthotel. The array of shops and top-notch restaurants are some of the places to enjoy during your visit. Sikeston is also known for its riverfront. ### What are some top aparthotels in Sikeston? > Located 60.5 mi (97.4 km) from Sikeston, [Urban Lofts](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) is a favorite aparthotel featuring 9 apartments with kitchens and free WiFi as well as hotel amenities like free parking. ### How many aparthotels are there in Sikeston? > On Expedia, you'll find 15 lodging options in Sikeston. Though you won't find many aparthotels, we can suggest places to stay that are similar such as a condo or apartment. ### What are the must-see places to visit in Sikeston? > Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the larger area, you'll find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery. ### What is an aparthotel? > An aparthotel or serviced apartment offers more space and privacy like an apartment and the amenities you expect from a traditional hotel. By booking an aparthotel, you can stay longer and absorb more of the local color in Sikeston. 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