Italy may have travel restrictions in place due to COVID-19.

Find out moreOpens in new tab or window

Hotels in Santissima Annunziata, Florence from CA $49

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Santissima Annunziata hotels and places to stay

Ostello 7 Santi
Viale Dei Mille 11, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $56 per night
3.8/5Good! (174 reviews)

"Decent distance from museums, about 30 min walkwalk"…"

Reviewed on Feb. 11, 2019

Ostello 7 Santi
Your "beautiful" View ON Florence!
27 Via della Colonna, Florence, Tuscany
Get Rates
5/5Exceptional! (4 reviews)
Fantastic Home to stay in while in Florence

"We had a wonderful stay at this property. Rosie was a delight, extremely passionate about her city and very helpful to us. The apartment is lovely and very well appointed. It was more than comfortable for 4 adults. The location is ideal, safe and had a very local vibe. We would stay again and certainly ..."…"

Reviewed on Jul. 26, 2019

Your "beautiful" View ON Florence!
Four Seasons Hotel Firenze
5 out of 5
Borgo Pinti, 99, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $1,096 per night
4.8/5Exceptional! (181 reviews)
My eternal smile

"It is rare that an elegant hotel is professional, elegant and fun. The Four Seasons in Florence, Italy has managed to achieve all of these qualities. Although we were there for my birthday, I wanted to surprise my friend with a pastry that she loves. We can not get it in the U.S. I asked the restaurant ..."…"

Reviewed on Apr. 10, 2020

Four Seasons Hotel Firenze
3 out of 5
Via Vittorio Alfieri 9, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $100 per night
4.8/5Exceptional! (68 reviews)

"Excellent boutique hotel. Could not fault"…"

Reviewed on Feb. 25, 2020

Hotel Astro Mediceo
3 out of 5
Via Frà Bartolommeo 54/56, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $76 per night
4.4/5Excellent! (251 reviews)

"The hotel had a lot of charm. The rooms were very clean, simple, and comfortable. Great down pillows and comforters.The breakfast was wonderful. Great place to stay in Florence."…"

Reviewed on Feb. 3, 2020

Hotel Astro Mediceo
My Forte Relais de Charme
Viale Antonio Gramsci 16/3, Lungarno del Tempio, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $155 per night
4.4/5Excellent! (38 reviews)

"We stayed here for 4 nights and loved it. We booked the family room with two different rooms (the main one with access to a little courtyard) and a shared bathroom, the set up was very good as the kids could be in bed and we could enjoy a glass of wine outside. Breakfast was very nice, not hot cooked ..."…"

Reviewed on Oct. 27, 2019

My Forte Relais de Charme
Bric à Brac
VIA MASACCIO 104, Florence
Free cancellationReserve now, pay when you stay
The price is CA $49 per night
4.5/5Wonderful! (6 reviews)

"Nice place, close to train station"…"

Reviewed on Jan. 5, 2020

Bric à Brac
Hotel Regency
5 out of 5
Piazza M. D'Azeglio, 3, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $1,242 per night
4.6/5Exceptional! (337 reviews)

"Loved everything about this hotel. Rooms were beautiful and comfortable and the staff were so helpful and friendly. Looking forward to visiting again one day."…"

Reviewed on Nov. 3, 2019

Hotel Regency
Messori Suites
Via Antonio Giacomini 25, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $93 per night
4.8/5Exceptional! (119 reviews)
Great place

"good location and a very comfortable room, and nice staff. They think about every little detail for your comfort. A very good place to stay when you go to Florence"…"

Reviewed on Jan. 8, 2020

Messori Suites
Palazzo Lombardo
Viale Dei Mille 6, Florence, FI
Free cancellationReserve now, pay when you stay
The price is CA $63 per night
4.1/5Very Good! (87 reviews)

"The lady at the front desk was very nice. As we were coming up the stairs she didn’t want us to carry up Incase we were at the wrong location. She also speak multiple languages like French Spanish English and Italian!"…"

Reviewed on Sep. 3, 2019

Palazzo Lombardo
Don't see what you're looking for?
See all available properties in Santissima Annunziata
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santissima Annunziata Hotels Guide offers a selection of 373 hotels in Santissima Annunziata. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. will not only save you time, but also money when booking your stay at a hotel in Santissima Annunziata. Making reservations so you can stay within your budget is easy with us. even provides you with a map so you may find hotels in the Santissima Annunziata neighborhood you prefer.

Go ahead. Enter your travel dates to view the best offers on hotel rooms in Santissima Annunziata, Florence now!

Frequently asked questions

What's it like in Santissima Annunziata?
Santissima Annunziata is a historic neighborhood known for its picturesque gardens and biking. Looking for sights you might find in a travel guide about Santissima Annunziata? Consider a visit to Gallery of the Academy of Florence while you’re in the neighborhood.
What's a favorite hotel to stay in Santissima Annunziata?
Based on Expedia customer reviews, Messori Suites is the highest ranked property in Santissima Annunziata. This B&B is a short 13-minute walk from Gallery of the Academy of Florence, and it offers free WiFi and a bar. Other favorite options in the area include Alfieri9 and Residenza Il Villino B&B.
How many hotels are there in the Santissima Annunziata area?
If you’re searching for places to stay in Florence, Expedia has something to meet your needs with 373 Santissima Annunziata hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santissima Annunziata, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if cancelled before the accommodation’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on “Search”, then filter by “free cancellation” to get the best deals in Santissima Annunziata.
What are the top things to see and do in Santissima Annunziata?
Attractions like Gallery of the Academy of Florence, Hospital of the Innocents, and National Archaeological Museum highlight Florence’s cultural scene. Palazzo Capponi and Great Synagogue of Florence are also a couple of places to visit in the neighborhood. Don’t miss favorite places to visit in the surrounding area, such as Piazza del Duomo, Cattedrale di Santa Maria del Fiore, and Piazza della Signoria. Palazzo Vecchio and Uffizi Gallery are also worth a visit when you’re out sightseeing in Florence.
How can I get around Santissima Annunziata and the greater Florence area?
If you want to head out of town, you can hop aboard a train at Florence Campo Di Marte Station.

Recent Reviews in Santissima Annunziata

More trip options