Northeast Missouri Vacation Packages

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Your Northeast Missouri Vacation

When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Centre and Busch Stadium. St. Charles is another top city that draws travellers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.

Top Northeast Missouri Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

CA $1,260
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8/10 Very good! (1,001 reviews)
The Wildwood Hotel

The Wildwood Hotel

CA $1,437
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
9.2/10 Wonderful! (1,679 reviews)
The room was super clean and the jacuzzi was such a fun touch!

Reviewed on Oct 12, 2026

The Cheshire

The Cheshire

CA $1,733
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.8/10 Excellent! (1,011 reviews)
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport
CA $1,345
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
7.8/10 Good! (1,005 reviews)
Saw two roaches in my room. There was cereal up and down the hall floor. No pillows or sheets for the pull out bed. Breakfast was picked over by 8 am.

Reviewed on Oct 11, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

CA $1,825
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.6/10 Excellent! (1,062 reviews)
Wonderful stay for a small bachelorette party. Had a wonderful time!

Reviewed on Oct 10, 2026

Where to stay in Northeast Missouri

Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

An ornate hall with arched ceilings and intricate patterns.

Downtown West

2 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Ready to book your vacation to Northeast Missouri?

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Northeast Missouri Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
CA $127
CA $148 total
Oct 25 - Oct 26
includes taxes & fees
9/10 Wonderful! (3,478 reviews)
"No comment. not applicable"

Reviewed on Oct 12, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
CA $128
CA $152 total
Oct 18 - Oct 19
includes taxes & fees
9.2/10 Wonderful! (3,298 reviews)
"Ants. The staff acted like it wasn’t the first time they heard about it."

Reviewed on Oct 12, 2026

Pear Tree Inn St. Louis Airport
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
CA $135
CA $179 total
Nov 1 - Nov 2
includes taxes & fees
Hollywood Casino & Hotel St. Louis
See all 2,998 properties in Northeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Northeast Missouri attractions

The Saint Louis Zoo sign with vines on the wall.

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
See properties
A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
See properties
A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
Photo by Carl Guttovz

Busch Stadium

9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A stone fountain with water cascading down a tiered structure, surrounded by a pond and a grassy area with a building in the background.

Forest Park

9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
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A colorful LEGO display with various shapes and figures.

Magic House - St. Louis Children's Museum

9.2/10 (184 reviews)
St. Louis’ Children’s Museum is packed with activities to make learning fun, from stocking supermarket shelves to building a firehouse.
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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.
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America's Center Convention Complex

8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's acclaimed art scene and great live music.
See properties

What to do in Northeast Missouri

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

CA $49
per adult
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds

Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds

CA $21
per adult
Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds
Kansas City Downtown Smartphone Guided Audio Walking Tour

Kansas City Downtown Smartphone Guided Audio Walking Tour

CA $11
per adult
Kansas City Downtown Smartphone Guided Audio Walking Tour
See all activities in Northeast Missouri

Frequently asked questions

How much does a Northeast Missouri vacation package cost?
Live it up in Northeast Missouri from as little as CA $1,260. Choose from a great selection of flights, hotels and rental cars to suit your travel style. You can score even more discounts when you add a few sightseeing activities to your vacation package.
How do I get a cheap travel package to Northeast Missouri?
Our Northeast Missouri vacation packages promise plenty of savings for the savvy explorer. For the best deal, simply bundle your flights, hotels and extras (including tours) into a handy package. But low prices are only the start of your next memorable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotel options around the globe to choose from. No matter your budget or style, there's a vacation package that's perfect for you.
Where should I stay in Northeast Missouri?
You'll love St. Louis. Popular attractions, like Busch Stadium and Gateway Arch, will keep you entertained in this happening city.
What are the top hotels in Northeast Missouri?
For properties in St. Louis with comfy beds and friendly service, you can't top Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay. If you're swinging by Wright City as well, you can look forward to a wonderful night's sleep at Holiday Inn Express Warrenton, an IHG Hotel or Super 7 Inn.
How far in advance should I book my Northeast Missouri vacation?
While not all airlines advertise ticket prices early, you can usually look up international flights on Expedia up to 12 months in advance. This is the time you'll bag some incredible deals. If you're booking late, you could still be in luck. Low prices sometimes become available a few weeks prior to departure.
What does an Expedia Northeast Missouri travel package include?
That depends on what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole crew to Northeast Missouri? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to customize your travel package.
What should I know before booking a Northeast Missouri travel package?
Discover deals that fit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save loads just for bundling your bookings. Whether you're embarking on a snow and ski adventure or kicking back on a warm beach, your dream getaway is only clicks away.
Can I choose my airline with a Northeast Missouri Expedia vacation package?
With a vacation package, the choice is in your hands. Whether you're hoping to fly to Northeast Missouri in business or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines globally.
If I'm not able to travel, can I cancel my Northeast Missouri vacation package?
If your vacation plans in Northeast Missouri have been upended, it's comforting to know that it's possible to amend or cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may impose a fee. To find out more, check our Customer Service Portal.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.