Northeast Missouri Vacation Packages
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Your Northeast Missouri Vacation
When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Centre and Busch Stadium. St. Charles is another top city that draws travellers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.
Top Northeast Missouri Vacation Deals
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
CA $837
per person
Oct 22 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
9.2/10 Wonderful! (1,665 reviews)
Absolutely BEAUTIFUL!! Small town, quiet, extremely friendly! Would recommend to everyone staying in the area!!
Reviewed on Aug 27, 2026
Hotel Indigo St Louis - Central West End by IHG
Central West End
CA $958
per person
Oct 22 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.8/10 Excellent! (1,008 reviews)
Sheets were not clean when we arrived. Room was never cleaned when we came back to sleep for the 2nd night.
Reviewed on Aug 24, 2026
Where to stay in Northeast Missouri
Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Downtown West
3 out of top 10 points of interest in this area
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Ready to book your vacation to Northeast Missouri?
Northeast Missouri Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
CA $129
CA $151 total
Sep 6 - Sep 7
includes taxes & fees
9/10 Wonderful! (3,339 reviews)
"great location and friendly staff...would certainly stay here again"
Reviewed on Aug 27, 2026
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
CA $136
CA $200 total
Sep 7 - Sep 8
includes taxes & fees
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
CA $176
CA $206 total
Sep 13 - Sep 14
includes taxes & fees
8.4/10 Very good! (1,175 reviews)
"I was disappointed with my stay. The carpets need to be cleaned. The bed wasn’t that comfortable. There was a huge bug stuck to the bottom of the revolving door when you initially come in. We had issues with the air conditioner. The staff was very nice! Would not stay again or recommend!"
Reviewed on Aug 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Northeast Missouri attractions
Photo by Carl Guttovz
Busch Stadium
9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Photo by Jeff White
St. Louis Zoo
9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Dome at America’s Center
8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.
Forest Park
9.2/10 (3,389 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
St. Louis University
8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
City Museum
9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
America's Center Convention Complex
8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
What to do in Northeast Missouri
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
CA $49
per adult
Kansas City Haunted Pub Crawl Ghostly Drinks and Stories
CA $49
per adult
Frequently asked questions
How much does a Northeast Missouri vacation package cost?
Live it up in Northeast Missouri from as little as CA $837. Choose from a great selection of flights, hotels and rental cars to suit your travel style. You can score even more discounts when you add a few sightseeing activities to your vacation package.
How do I get a cheap travel package to Northeast Missouri?
Our Northeast Missouri vacation packages promise plenty of savings for the savvy explorer. For the best deal, simply bundle your flights, hotels and extras (including tours) into a handy package. But low prices are only the start of your next memorable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotel options around the globe to choose from. No matter your budget or style, there's a vacation package that's perfect for you.
Where should I stay in Northeast Missouri?
You'll love St. Louis. Popular attractions, like Busch Stadium and Gateway Arch, will keep you entertained in this happening city.
What are the top hotels in Northeast Missouri?
For properties in St. Louis with comfy beds and friendly service, you can't top Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay. If you're swinging by Wright City as well, you can look forward to a wonderful night's sleep at Holiday Inn Express Warrenton, an IHG Hotel or Super 7 Inn.
How far in advance should I book my Northeast Missouri vacation?
While not all airlines advertise ticket prices early, you can usually look up international flights on Expedia up to 12 months in advance. This is the time you'll bag some incredible deals. If you're booking late, you could still be in luck. Low prices sometimes become available a few weeks prior to departure.
What does an Expedia Northeast Missouri travel package include?
That depends on what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole crew to Northeast Missouri? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to customize your travel package.
What should I know before booking a Northeast Missouri travel package?
Discover deals that fit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save loads just for bundling your bookings. Whether you're embarking on a snow and ski adventure or kicking back on a warm beach, your dream getaway is only clicks away.
Can I choose my airline with a Northeast Missouri Expedia vacation package?
With a vacation package, the choice is in your hands. Whether you're hoping to fly to Northeast Missouri in business or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines globally.
If I'm not able to travel, can I cancel my Northeast Missouri vacation package?
If your vacation plans in Northeast Missouri have been upended, it's comforting to know that it's possible to amend or cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may impose a fee. To find out more, check our Customer Service Portal.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
