COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Mexico Vacation Rentals

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Vacation Rentals in Mexico

Spencer Estate Blue Room

Spencer Estate Blue Room

Mexico, MO
The price is CA $169 per night from Apr 23 to Apr 24
Situated in Mexico, this vacation home is within 1 mi (2 km) of Hillside Mini Golf, Presser Performing Arts Center, and Audrain County Historical Society. American ...
5/5Exceptional! (1 review)
Snow Seeker
"Can’t say enough kind words about the property owner, thoroughly enjoyed our visit with her by the fire pit 😊 Although we were there in January, it is evident the home and grounds are very well kept and spectacular in the spring/summer season. We reserved the guest house, a lovely private space ..."

Reviewed on Jan. 7, 2021

Spencer Estate Blue Room
Private Room in Victorian Home Surrounded by English Gardens

Private Room in Victorian Home Surrounded by English Gardens

Mexico, MO
The price is CA $169 per night from Apr 24 to Apr 25
Situated in Mexico, this vacation home is within 1 mi (2 km) of Hillside Mini Golf, Presser Performing Arts Center, and Audrain County Historical Society. American ...
Private Room in Victorian Home Surrounded by English Gardens
Lakefront Columbia Cabin w/ Views & Porch!

Lakefront Columbia Cabin w/ Views & Porch!

Columbia, MO
Situated on the waterfront, this cabin is 2.9 mi (4.6 km) from Mark Twain National Forest and within 12 mi (20 km) of Serenity Valley Winery and Landmark Hospital. ...
4.8/5Exceptional! (13 reviews)
Fantastic Time!
"We wanted to have a nice local getaway and settled on this semi-remote cabin on the lake. The boats can be obtained rent free. The management team has a constant presence which i found comforting. My only complaint is that the online description says that you can contact the management if there are ..."

Reviewed on Sep. 11, 2020

Lakefront Columbia Cabin w/ Views & Porch!
You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Rustic Log Cabin on Mark Twain Lake

Rustic Log Cabin on Mark Twain Lake

Stoutsville, MO
Situated on a lake, this cabin is within 6 mi (10 km) of Mark Twain State Park, Mark Twain State Park Beach, and Mark Twain Birthplace State Historic Site. Mark ...
4.9/5Exceptional! (11 reviews)
Get away from it all
"The property was a great little get away, perfect for a weekend with someone special or a family. The owners are very easy to work with and communication is great. Definitely would go back!"

Reviewed on Mar. 28, 2021

Rustic Log Cabin on Mark Twain Lake
New! Cozy Perry Cabin - 8 Mi to Mark Twain Lake!

New! Cozy Perry Cabin - 8 Mi to Mark Twain Lake!

Perry, MO
Located in the heart of Perry, this cabin is within 12 mi (20 km) of Mark Twain State Park, Mark Twain Birthplace State Historic Site, and Mark Twain State Park ...
New! Cozy Perry Cabin - 8 Mi to Mark Twain Lake!
Luxury Modern Downtown Columbia Lofts. 2 Beds, 2 Baths

Luxury Modern Downtown Columbia Lofts. 2 Beds, 2 Baths

Columbia, MO
The price is CA $281 per night from Apr 25 to Apr 26
Located in North Central Columbia, this apartment building is within a 15-minute walk of Stephens College and University of Missouri. Mizzou Arena is 1.7 mi ...
4.9/5Exceptional! (40 reviews)
Great location
"Great location, parked literally steps from door. Would highly recommend."

Reviewed on Apr. 2, 2021

Luxury Modern Downtown Columbia Lofts. 2 Beds, 2 Baths
The Night Owl Cottage

The Night Owl Cottage

Columbia, MO
Situated in Columbia, this vacation home is 1.9 mi (3.1 km) from Missouri Heart Institute and 2.8 mi (4.5 km) from University of Missouri. Boone Hospital Center ...
4.5/5Wonderful! (2 reviews)
Mizzou Dad’s weekend at the Nite Owl Cottage
"We really enjoyed the cottage and the beautiful property. It was a better alternative than a hotel room while visiting our daughter at Mizzou. Cottage was clean, cozy and quiet."

Reviewed on Sep. 24, 2019

The Night Owl Cottage
Mark Twain Lake Condo

Mark Twain Lake Condo

Monroe City, MO
Situated in Monroe City, this condo building is within 25 mi (40 km) of Hannibal Regional Hospital, Mark Twain Lake, and Mark Twain Birthplace State Historic ...
4.5/5Wonderful! (2 reviews)
Clean, spacious condo
"We stayed in the Hannibal MO area for a short trip. We wanted to be out of town for quiet and relaxation. We felt the location was nice, quiet, 30 minutes to Hannibal, 45 to Quincy Il. The condo was clean, had all the amenities in the listing, ie games, soap, towels."

Reviewed on Apr. 8, 2021

Mark Twain Lake Condo
Celebrate Christmas in a Rustic Log Home

Celebrate Christmas in a Rustic Log Home

Auxvasse, MO
The price is CA $500 per night from Apr 19 to Apr 20
5/5Exceptional! (2 reviews)
Perfect Christmas Getaway
"Our daughter is in her last year of veterinary school at Mizzou and was on-call for Christmas. She couldn't come home so we went to her. The log cabin was a perfect getaway and only 35 minutes to Columbia. The house was beautifully decorate for Christmas! It is secluded and on a large piece of land. ..."

Reviewed on Dec. 30, 2020

Celebrate Christmas in a Rustic Log Home
Downtown/close to Stadium 4-bedroom Ranch House Entertaining Set Up

Downtown/close to Stadium 4-bedroom Ranch House Entertaining Set Up

Columbia, MO
The price is CA $688 per night from Apr 25 to Apr 26
Situated in Columbia, this vacation home is within 3 mi (5 km) of Faurot Field, University of Missouri, and Mizzou Arena. Columbia Mall is 2.6 mi (4.1 km) ...
Downtown/close to Stadium 4-bedroom Ranch House Entertaining Set Up
Don't see what you're looking for?
See all available properties in Mexico
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Mexico you may be interested in

Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

2 out of 5
2902 S. Clark, Mexico, MO
Free cancellationReserve now, pay when you stay
The price is CA $83 per night from Apr 24 to Apr 25
Days Inn by Wyndham Mexico
Best Western Teal Lake Inn

Best Western Teal Lake Inn

2.5 out of 5
3602 S Clark St, Mexico, MO
Free cancellationReserve now, pay when you stay
The price is CA $138 per night from Apr 19 to Apr 20
Best Western Teal Lake Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.