The best area to stay in Mexico, Missouri, is near the town centre, particularly around the intersection of West Liberty Street and South Muldrow Street.This central area is the most convenient for visitors, offering easy access to local amenities and attractions. It's where you'll find the historic downtown square. Accommodations here often include hotels with modern conveniences, making it a comfortable base for exploring.For couples or those seeking a relaxed stay, choosing a hotel within walking distance of the Audrain County Historical Society or the Graceland Museum offers a pleasant experience. You'll be close to local eateries and shops, superb for an evening stroll.Business travellers will also find this central location ideal due to its proximity to local businesses and the main thoroughfares.