Name: Comfort Suites St Charles - St Louis
Price range: CA $128
Rating: 8.4

Your St. Charles Vacation

Spend less time planning and more time having fun adventures with a St. Charles vacation package. The neighborhood of Old Jamestown, which is great for nature and walking, makes a great base for your city escape. Fill your free time with tours of Ameristar Casino St. Charles, Hollywood Casino Amphitheatre and Historic Main Street, some of the top attractions you just have to see during a trip to St. Charles. A couple of clicks is all it takes to build your perfect St. Charles vacation on Expedia.

Top St. Charles Vacation Deals

Price found within the past 48 hours. Click for updated prices.

River City Casino & Hotel

CA $798

per person

Jun 1 - Jun 5

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to St. Louis (STL)

9.2/10 Wonderful! (1,521 reviews)

Excellent except our room wasn't ready to ck in till after 8pm!

Reviewed on Apr 25, 2026

Nebraska

Benton Park West

CA $2,560

per person

Jun 1 - Jun 5

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to St. Louis (STL)

No reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

CA $1,097

per person

Jun 1 - Jun 5

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to St. Louis (STL)

8.8/10 Excellent! (1,059 reviews)

Room with Queen bed was very basic and not worth $500 one night stay. Table in room was dusty and no microwave provided in room. bed was extremely comfortable though.

Reviewed on Apr 25, 2026

The Knight Center at Washington University

CA $1,015

per person

Jun 1 - Jun 5

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to St. Louis (STL)

9.4/10 Exceptional! (523 reviews)

Uneven front desk team. Some incredibly caring & friendly. Some downright rude. For $400/night, you are paying for the convenience of being on campus. Amenities basic.

Reviewed on Apr 19, 2026

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

CA $1,495

per person

Jun 1 - Jun 5

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to St. Louis (STL)

8.8/10 Excellent! (1,030 reviews)

Dated property, no closet, nice bed.

Reviewed on Apr 24, 2026

Ready to book your vacation to St. Charles?

Choose your dates

St. Charles Hotel Deals

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

CA $218

CA $277 total

Apr 27 - Apr 28

includes taxes & fees

8.6/10 Excellent! (1,004 reviews)

The outside hot tub was very cold, indoor hot tub was nice but not hot. The room was amazing and it was such an experience. I will definitely be staying here again.

Reviewed on Apr 24, 2026

Drury Plaza Hotel St. Louis St. Charles

380 Mulholland Drive St. Charles MO

Fully refundableReserve now, pay when you stay

CA $198

CA $230 total

May 10 - May 11

includes taxes & fees

9.6/10 Exceptional! (1,006 reviews)

Elevator out of service

Reviewed on Apr 25, 2026

Comfort Suites St Charles - St Louis

1400 S 5th St St. Charles MO

Fully refundable

CA $128

CA $147 total

May 3 - May 4

includes taxes & fees

8.4/10 Very Good! (1,002 reviews)

This was the most awful experience ever got there on Thursday April 23rd and got in the room a none smoking room someone had been smoking got moved to another room it hqd bed bigs have proof videos and pictures had to stay there wasnt any hotels available because of a event in town left as fast as ...

Reviewed on Apr 25, 2026

See all 2,391 properties in St. Charles

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.