Historic Main Street Tours and Activities
Visit Historic Main Street
Plan a trip to see Historic Main Street

Hilton Garden Inn Chesterfield
Reviewed on Jul. 26, 2025


Home2 Suites by Hilton St. Louis Downtown
Reviewed on Aug. 1, 2025
Popular places to visit

Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this family-friendly area.
First Missouri State Capitol Historic Site
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
SSM Health St. Joseph Hospital
Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.
Lewis & Clark Boathouse and Nature Center
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
Frenchtown Heritage Museum
You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
Best Lodging Options Near Historic Main Street
Check availability on hotels close to Historic Main Street

Hollywood Casino & Hotel St. Louis

The St. Charles Guest House, lovely historic home, fun for families and groups

Ameristar Casino Resort and Spa

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

Country Inn & Suites by Radisson, St. Charles Historic District

HUGE 2 bedroom unit on Main Street

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

Luxurious couples retreat just steps from Historic Main Street in St. Charles!

The Wild West Getaway- 204-1
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Vacations and getaways similar to Historic Main Street
- Other Hotels near Historic Main Street, St. Charles Historic District
- Hotels near popular St. Louis Attractions
- More Hotel Options in Historic Main Street
- 3BR Historic St. Charles, MO-Walking distance to Main Street
- Relaxing South Main Apartment with Modern Comforts
- Scenic South Main Apartment with Breathtaking Views for 3 Guests
- The Historic Bricks on Main
- Western-Themed 2-Bedroom Hideout for Outlaws 204-2
- Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
- Walking distance to Historic Main Street, St. Charles, MO
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near Westport Plaza
- Hotels near Hollywood Casino
- Hotels near St Charles Convention Center
- Hotels near Saint Louis Galleria Mall
- Hotels near Missouri River
- Hotels near Lindenwood University
- Hotels near St. Louis Premium Outlets
- Hotels near Family Arena
- Hotels near The Factory
- Hotels near Lou Fusz Soccer Complex
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near SSM Health Rehabilitation Hospital
- Hotels near Mid Rivers Mall
- Hotels near CarShield Field
- Hotels near Centene Community Ice Center