Title: Book The Best Hotels in Greencastle, MO for 2025 from CA $90 - Competitive Prices - Expedia.ca [Vacation Rentals in Greencastle](https://expedia.ca/Greencastle-Vacation-Rentals.d553248634983462000.Travel-Guide-VacationRentals)[Greencastle Car Rentals](https://expedia.ca/Car-Rentals-In-Greencastle.d553248634983462000.Car-Rental-Guide)[Greencastle Vacation Packages](https://expedia.ca/Greencastle.d553248634983462000.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Greencastle, MO from CA $90 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Greencastle Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Greencastle%2C+Missouri%2C+United+States+of+America®ionId=553248634983462000&latLong=40.262523%2C-92.877981&adults=2&startDate=2025-11-27&d1=2025-11-27&endDate=2025-11-29&d2=2025-11-29&amenities=PETS) ## Check prices for these dates Tonight [Nov 13 - Nov 14](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-11-13&endDate=2025-11-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 14 - Nov 15](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-11-14&endDate=2025-11-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248634983462000&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 45 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/59d144bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/093bb3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/f3c5f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Kirksville Kirksville 6.6/10 (1000) "Breakfast was great enjoyed the pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dara CA $80 CA $90 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator & Microwave](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/3ced37b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/0822c1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/ebcfa50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Kirksville Kirksville 9.2/10 Wonderful (562) "Clean and very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $162 CA $184 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/a6904e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/06554a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio Suite, 1 King Bed, Non Smoking | Jetted tub](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/b428c708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Kirksville University Area Kirksville 7.6/10 Good (892) "Our room was very clean, as was the hallway and lobby. The bed was comfortable. I think there has been a recent remodel. We will stay here again when visiting Kirksville." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $96 CA $108 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/4afe2a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/9c660a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/d203c711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Kirksville-University Area Kirksville 9.0/10 Wonderful (131) "Clean room, quick check in, very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $91 CA $102 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/a8e8f4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/35d9f717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/781fda5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Kirksville - University Area by IHG Kirksville 9.2/10 Wonderful (499) "Staff was polite and helpful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rochelle CA $167 CA $189 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/74b6e2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/45e37c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/7d76c669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kirksville Kirksville 7.6/10 Good (391) "It was clean and quiet, check went smooth i was worried alittle some review said bad and others said good i guess are stay was good i would d tay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) david CA $93 CA $120 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9afc2091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/9b5928a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/cf6ce139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Kirksville Kirksville 7.2/10 Good (249) "Cozy and cool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lois CA $95 CA $107 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-27&endDate=2025-11-28®ionId=553248634983462000&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGreencastle-Hotels.d553248634983462000.Travel-Guide-Hotels) ## More cheap stays in Greencastle ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr, Kirksville, MO CA $91 CA $102 total Nov 23 - Nov 24 includes taxes & fees 8.8/10 Excellent! (129 reviews) [](https://expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Kirksville 3805 S Baltimore St, Kirksville, MO CA $80 CA $90 total Nov 26 - Nov 27 includes taxes & fees 6.6/10 (1,001 reviews) [](https://expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Baymont by Wyndham Kirksville University Area](https://images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Kirksville University Area 2702 South Franklin, Kirksville, MO CA $96 CA $108 total Nov 26 - Nov 27 includes taxes & fees 7.6/10 Good! (892 reviews) [](https://expedia.ca/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Kirksville 2604 N. Baltimore Street, Kirksville, MO CA $162 CA $184 total Nov 28 - Nov 29 includes taxes & fees 9/10 Wonderful! (561 reviews) [](https://expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 2523 South Franklin St., Kirksville, MO CA $167 CA $189 total Nov 23 - Nov 24 includes taxes & fees 9.2/10 Wonderful! (499 reviews) [](https://expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Quality Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/20500/20482/2dd82658_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Kirksville 2209 N Baltimore St, Kirksville, MO CA $93 CA $120 total Nov 23 - Nov 24 includes taxes & fees 7.4/10 Good! (390 reviews) [](https://expedia.ca/Macon-Hotels-Quality-Inn-Kirksville.h20482.Hotel-Information) ## Hotels in Greencastle with star-rating ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_w.jpg) 2 Star Hotels 10 properties [](https://expedia.ca/2Star-Greencastle-Hotels.s20-0-d553248634983462000.Travel-Guide-Filter-Hotels) ## Recent reviews of Greencastle hotels ![Holiday Inn Express & Suites Kirksville - University Area by IHG](//images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 5/5 Excellent "Staff was polite and helpful!" A verified traveller stayed at Holiday Inn Express & Suites Kirksville - University Area by IHG Posted 2 days ago [](https://expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Hampton Inn Kirksville](//images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg) ### Hampton Inn Kirksville 5/5 Excellent "The king suite was HUGE! So much room for activities! And they had hot coffee available in the lobby when we came in at 9pm. Awesome stay!" A verified traveller from TROY stayed at Hampton Inn Kirksville Posted 3 days ago [](https://expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information) ![Thousand Hills](//images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg) ### Thousand Hills 5/5 Excellent "Room was in great shape and close to actities I did" A verified traveller stayed at Thousand Hills Posted 4 days ago [](https://expedia.ca/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information) ![Baymont by Wyndham Kirksville University Area](//images.trvl-media.com/lodging/1000000/130000/125500/125458/0cfe6b5f_y.jpg) ### Baymont by Wyndham Kirksville University Area 5/5 Excellent "Our room was very clean, as was the hallway and lobby. The bed was comfortable. I think there has been a recent remodel. We will stay here again when visiting Kirksville." A verified traveller stayed at Baymont by Wyndham Kirksville University Area Posted 4 days ago [](https://expedia.ca/Macon-Hotels-Baymont-By-Wyndham-Kirksville-University-Area.h125458.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](//images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 5/5 Excellent "Clean room friendly staff and surprised they had a hot breakfast. Good price as compared to other motels nearby." A verified traveller stayed at Super 8 by Wyndham Kirksville-University Area Posted 5 days ago [](https://expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![Days Inn by Wyndham Kirksville](//images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg) ### Days Inn by Wyndham Kirksville 4/5 Good "Room was decent " A verified traveller stayed at Days Inn by Wyndham Kirksville Posted 5 days ago [](https://expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information) ![Knights Inn Kirksville](//images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d_y.jpg) ### Knights Inn Kirksville 5/5 Excellent "Cozy and cool." A verified traveller stayed at Knights Inn Kirksville Posted 9 days ago [](https://expedia.ca/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information) ![New tiny home in an incredible private setting among all nature has to offer.](//images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg) ### New tiny home in an incredible private setting among all nature has to offer. 5/5 Excellent "Incredible stay! Jason and Joyce are extremely welcoming and " A verified traveller stayed at New tiny home in an incredible private setting among all nature has to offer. Posted 10 days ago [](https://expedia.ca/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information) ![Country's Edge Retreat](//images.trvl-media.com/lodging/121000000/120070000/120065000/120064921/58c67ab5_y.jpg) ### Country's Edge Retreat 5/5 Excellent "Very clean, everything was as stated, extremely convenient and will definitely stay again! " A verified traveller stayed at Country's Edge Retreat Posted 12 days ago [](https://expedia.ca/Greentop-Hotels-Countrys-Edge-Retreat.h120064921.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Greencastle. ### How can I save on a Greencastle hotel booking with Expedia? > Before booking your Greencastle hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Greencastle hotel? > Prices for hotels in Greencastle often vary, but you can find a great deal from CA $90 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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