Photo by Andrew Hershfeld
Find hotels in Northeast Missouri, MO from CA $105
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Northeast Missouri
Check prices for these dates
Our top choices for Northeast Missouri hotels
Best Western On The River
Best Western On The RiverHannibal
8.6 out of 10, Excellent, (1,016 reviews)
"Clean rooms, decent breakfast"
Christina
The price is CA $168
CA $194 total
includes taxes & fees
Jul 13 - Jul 14
Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal WestHannibal
8.0 out of 10, Very good, (1,005 reviews)
"Pet friendly hotel. The staff is amazingly friendly. The room was excellent. Nothing bad to say at all. This was our 2nd stay there and we will be going back!!!!"
Sandra
The price is CA $118
CA $138 total
includes taxes & fees
Aug 2 - Aug 3
Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal WestHannibal
9.6 out of 10, Exceptional, (1,003 reviews)
"Room was great and breakfast was fantastic "
Sheila
The price is CA $156
CA $181 total
includes taxes & fees
Aug 2 - Aug 3
Depot Inn and Suites
Depot Inn and SuitesLa Plata
9.8 out of 10, Exceptional, (687 reviews)
"Great little hotel, lots of character."
Carol
The price is CA $153
CA $166 total
includes taxes & fees
Jul 22 - Jul 23
Oak Hill Inn & Suites
Oak Hill Inn & SuitesCanton
9.2 out of 10, Wonderful, (984 reviews)
"Breakfast was good, room was clean, and staff was nice!"
Kaia
The price is CA $140
CA $160 total
includes taxes & fees
Jul 10 - Jul 11
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
7.8 out of 10, Good, (1,417 reviews)
"Will definitely stay again!"
Trevor
The price is CA $134
CA $155 total
includes taxes & fees
Jul 9 - Jul 10
Super 8 by Wyndham Kirksville-University Area
Super 8 by Wyndham Kirksville-University AreaKirksville
9.0 out of 10, Wonderful, (240 reviews)
"Well maintained, recently redecorated, nice staff, small rooms."
tjimothy
The price is CA $102
CA $115 total
includes taxes & fees
Jul 18 - Jul 19
Hampton Inn Kirksville
Hampton Inn KirksvilleKirksville
9.2 out of 10, Wonderful, (652 reviews)
"Our room was clean and the breakfast was excellent!"
Marjorie
The price is CA $174
CA $197 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express & Suites St Peters by IHG
Holiday Inn Express & Suites St Peters by IHGSt. Peters
9.4 out of 10, Exceptional, (423 reviews)
"Great stay. Easy and quick check in."
John
The price is CA $143
CA $173 total
includes taxes & fees
Jul 19 - Jul 20
Pinemark Inn & Suites
Pinemark Inn & SuitesSt. Clair
9.6 out of 10, Exceptional, (1,005 reviews)
"Loved it, would definitely visit again"
Brandi
The price is CA $169
CA $185 total
includes taxes & fees
Jul 12 - Jul 13
Best Western St. Louis Inn
Best Western St. Louis InnSt. Louis
8.4 out of 10, Very good, (1,026 reviews)
"Rooms were clean, nice staff"
Hamdija
The price is CA $112
CA $129 total
includes taxes & fees
Jul 19 - Jul 20
Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (1,005 reviews)
"Good location."
Kristin
The price is CA $119
CA $134 total
includes taxes & fees
Jul 22 - Jul 23
River City Casino & Hotel
River City Casino & HotelSt. Louis
9.2 out of 10, Wonderful, (1,656 reviews)
"Friendly staff and clean room, great value"
Christian
The price is CA $134
CA $176 total
includes taxes & fees
Jul 12 - Jul 13
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis AirportSt. Ann
9.2 out of 10, Wonderful, (3,079 reviews)
"A one night stay, very helpful and friendly staff, will stay again."
phillip
The price is CA $138
CA $162 total
includes taxes & fees
Jul 22 - Jul 23
The Wildwood Hotel
The Wildwood HotelWildwood
9.2 out of 10, Wonderful, (1,671 reviews)
"Very nice hotel for the price! Would definitely stay there again in the future!"
Lori
The price is CA $138
CA $161 total
includes taxes & fees
Jul 21 - Jul 22
Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (366 reviews)
"Was a good place to stay"
Blake
The price is CA $135
CA $156 total
includes taxes & fees
Jul 12 - Jul 13
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,047 reviews)
"Easy access to the building was clean and friendly staff good breakfast and good internet ."
Joseph
The price is CA $119
CA $140 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,009 reviews)
"Very kid friendly. Love the popcorn and buffet, makes life super easy after a long day of travel."
Kiley
The price is CA $156
CA $180 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express & Suites Kirksville - University Area by IHG
Holiday Inn Express & Suites Kirksville - University Area by IHGKirksville
9.2 out of 10, Wonderful, (544 reviews)
"Very clean and close to town. Breakfast was good, all of the staff we encountered were kind."
Andrea
The price is CA $168
CA $190 total
includes taxes & fees
Jul 19 - Jul 20
Heritage Hotel Quincy
Heritage Hotel QuincyQuincy
8.8 out of 10, Excellent, (402 reviews)
"Great spot for the week."
John
The price is CA $100
CA $113 total
includes taxes & fees
Jul 13 - Jul 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Northeast Missouri
Cabin
9.2 out of 10, Wonderful, (20 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Northeast Missouri attractions
Learn more about Northeast Missouri
Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.
Top Northeast Missouri Hotel Reviews
Pear Tree Inn St. Louis Near Union Station
10/10 Excellent
More cheap stays in Northeast Missouri
Motel 6 Hazelwood, MO
5781 Campus Ct Hazelwood MO
The price is CA $86 per night from Jul 22 to Jul 23
CA $86
CA $105 total
Jul 22 - Jul 23
includes taxes & fees
8.4/10 Very good! (2,099 reviews)
Hotels in Northeast Missouri with star rating
5 Star Hotels
1 properties
Explore a world of travel with Expedia
- Days Inn by Wyndham Mexico
- Bethel Hotels
- Macon Hotels
- Shelbyville Hotels
- B&B in Palmyra
- Condo Rentals in Hannibal
- Apartments in Elmer
- Shelbina Hotels
- Cottages in Hunnewell
- Stoutsville Hotels
- Kahoka Hotels
- Comfort Inn & Suites Macon
- Purdin Hotels
- Cabin Rentals in Ralls County
- B&B in Northeast Missouri
- Condo Rentals in Alexandria
- Days Inn by Wyndham Hannibal
- Renick Hotels
- West Quincy Hotels
- B&B in Linn County
- Greencastle Hotels
- Bevier Hotels
- Condo Rentals in Frankford
- Cottages in Wyaconda
- Cabin Rentals in Wayland
- Cabin Rentals in Stoutsville
- Motels in Paris
- Vacation Homes in La Belle
- Vandalia Hotels
- Hampton Inn Kirksville
- Aimbridge Hospitality Hotels in Mexico
- Browning Hotels
- Farmstay in Ashburn
- Monroe City Hotels
- Cabin Rentals in Hannibal
- America's Value Inn Mexico
- Aparthotels in Green City
- Condo Rentals in Clark
- Pet-Friendly Hotels in Moberly
- Hannibal Hotels
- Motels in Alexandria
- Lodges in Chariton County
- Cabin Rentals in Holliday
- Cabin Rentals in Clark
- Fairbridge Inn Express
- Millard Hotels
- Days Inn by Wyndham Kirksville
- Farmstay in Benton City
- Cabin Rentals in Lentner
- New Cambria Hotels
- B&B in Novinger
- Best Western On The River
- Howard Johnson BY Wyndham Hannibal
- Apartments in Madison
- 5 Star Hotels in Mexico
- Marceline Hotels
- Paris Hotels
- Cabin Rentals in Livonia
- Flights from Grand Island (GRI) to Kirksville (IRK)
- Flights from Hannibal
- Flights from Vancouver (YVR) to Kirksville (IRK)
- Flights from Gibbs
- Flights to Kirksville
- Flights from Bucklin
- Flights to Mexico
- Flights from Queen City
- Flights from Toronto (YYZ) to Kirksville (IRK)
- Flights from Moberly
- Flights from Mexico
- Flights from Calgary (YYC) to Kirksville (IRK)
- Flights to Moberly
- Flights from Chicago (CHI) to Kirksville (IRK)
- Flights to Macon
