A large eye sculpture in a park surrounded by trees.

4 Stars Hotels in Northeast Missouri, Missouri from CA $146

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Check availability on Northeast Missouri 4 Star Hotels

Our top choices for Northeast Missouri 4-star hotels

1. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
The price is CA $203
CA $244 total
includes taxes & fees
Dec 8 - Dec 9
21C Museum Hotel St Louis

2. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,200 reviews)
"Great Hotel."
United States
Joy
The price is CA $157
CA $184 total
includes taxes & fees
Nov 27 - Nov 28
Renaissance St. Louis Airport Hotel

3. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,058 reviews)
"Cool hotel!"
United States
Rebecca
The price is CA $197
CA $234 total
includes taxes & fees
Nov 16 - Nov 17
Moonrise Hotel

4. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,366 reviews)
"Great place to stay."
United States
brandon
The price is CA $196
CA $233 total
includes taxes & fees
Nov 15 - Nov 16
Live by Loews - St.Louis

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,094 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
The price is CA $225
CA $286 total
includes taxes & fees
Nov 16 - Nov 17
Ameristar Casino Resort and Spa

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,008 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is CA $210
CA $290 total
includes taxes & fees
Nov 22 - Nov 23
The Royal Sonesta Chase Park Plaza St. Louis

7. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (802 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is CA $215
CA $253 total
includes taxes & fees
Nov 22 - Nov 23
Le Méridien St. Louis Clayton

8. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is CA $173
CA $202 total
includes taxes & fees
Nov 23 - Nov 24
The Westin St. Louis

9. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,004 reviews)
"Was a great stay"
United States
Loney
The price is CA $201
CA $242 total
includes taxes & fees
Nov 21 - Nov 22
Marriott St. Louis Airport

10. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,843 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is CA $107
CA $146 total
includes taxes & fees
Dec 10 - Dec 11
River City Casino & Hotel

11. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,007 reviews)
"The nicest room for the best price at this location. We stay in St Louis once per year and this was the best room! Love the proximity to the dome, and riverfront as well as nice restaurants"
United States
MARY BETH
The price is CA $179
CA $213 total
includes taxes & fees
Nov 22 - Nov 23
Marriott St. Louis Grand

12. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,410 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
The price is CA $134
CA $160 total
includes taxes & fees
Nov 26 - Nov 27
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

13. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,011 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is CA $181
CA $215 total
includes taxes & fees
Nov 22 - Nov 23
Drury Plaza Hotel St. Louis Brentwood

14. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,007 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is CA $210
CA $250 total
includes taxes & fees
Nov 29 - Nov 30
The Cheshire

15. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,370 reviews)
"Loved our stay!"
United States
Megan
The price is CA $149
CA $177 total
includes taxes & fees
Dec 10 - Dec 11
Embassy Suites by Hilton St. Louis Downtown

16. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,175 reviews)
"Loved the hotel!"
United States
Stephanie
The price is CA $146
CA $172 total
includes taxes & fees
Nov 24 - Nov 25
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

17. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,290 reviews)
"AMAZING STAY! AMAZING VIEWS FEOM ROOFTOP BAR!"
United States
Kella
The price is CA $196
CA $233 total
includes taxes & fees
Nov 23 - Nov 24
Hilton St. Louis at the Ballpark

18. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,004 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
The price is CA $219
CA $260 total
includes taxes & fees
Nov 24 - Nov 25
St. Louis Union Station Hotel, Curio Collection by Hilton

19. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,163 reviews)
"I enjoyed my stay and parking was safe."
United States
Jacqueline
The price is CA $155
CA $181 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Pennywell St. Louis at the Arch

20. DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport
4.0 star property
Woodson Terrace
7.8 out of 10, Good, (1,004 reviews)
"Great place!!"
United States
Kimberly
The price is CA $136
CA $160 total
includes taxes & fees
Nov 23 - Nov 24
DoubleTree by Hilton St. Louis Airport
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Northeast Missouri.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
The price is CA $790 per night from Nov 27 to Nov 28
CA $790
CA $922 total
Nov 27 - Nov 28
includes taxes & fees
9.2/10 Wonderful! (588 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld
Open Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

Find out more about Northeast Missouri

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Northeast Missouri are calling your name. Known for providing first-rate service in amazing locations, each of the Northeast Missouri 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Northeast Missouri. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Northeast Missouri, Missouri, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Northeast Missouri hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

What are the best 4-star hotels in Northeast Missouri?
If your Northeast Missouri getaway leads you to St. Louis, check in to St. Louis Union Station Hotel, Curio Collection by Hilton. With loads of amenities such as a swimming pool and concierge services, it gets high marks from many of our customers. Another popular pick in this city is 21C Museum Hotel St Louis. It's also rated 4 stars and comes with a swimming pool and concierge services.
How much does it cost to stay in a 4-star hotel in Northeast Missouri?
With Expedia's sort and search filters, bagging a superb deal on a 4-star hotel in Northeast Missouri just got easier. Start by keying in your chosen travel dates and length of your getaway. Then list the results by price and pick a property that best matches your budget and style.

  • Search for the lowest price from CA $922

What's the difference between 5-star and 4-star hotels in Northeast Missouri?
If you decide to spend your vacation at a 4-star hotel in Northeast Missouri, you'll typically find plenty of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience excellent service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few extra bells and whistles — think on-site spas, around-the-clock concierge and indulgent turndown services. You'll most likely get extra amenities and premium services at a 5-star stay, but both are great options for luxury guests.

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