Northeast Missouri Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Andrew Hershfeld

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Northeast Missouri Vacation

When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Centre and Busch Stadium. St. Charles is another top city that draws travellers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.

Top Northeast Missouri Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Rockwood Resort Motel

Rockwood Resort Motel

2.5 out of 5
Price was CA $1,309, price is now CA $1,287 per person
CA $1,287
per person
Aug 1 - Aug 8
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
8/10 Very Good! (51 reviews)
Just an older hotel but was clean and convenient to the area we wanted to stay.

Reviewed on May 6, 2026

Buddy's Harbor

Buddy's Harbor

2.5 out of 5
Price was CA $1,737, price is now CA $1,595 per person
CA $1,595
per person
Aug 1 - Aug 8
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
9.4/10 Exceptional! (48 reviews)
We stayed with my family of 6 adults and 4 kids, and we thoroughly enjoyed the property. The access to the lake is convenient, the staff is friendly and the cottages are amazing. They have thought about every small detail. Would certainly come back.

Reviewed on May 26, 2026

Prime Spot, Breathtaking Views, Nearby Attractions

Prime Spot, Breathtaking Views, Nearby Attractions

2 out of 5
Price was CA $1,807, price is now CA $1,710 per person
CA $1,710
per person
Aug 1 - Aug 8
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
No reviews
Latibe Retreat Lakefront Condo for 4 w/ Balcony & Pool Access

Latibe Retreat Lakefront Condo for 4 w/ Balcony & Pool Access

4 out of 5
Price was CA $1,879, price is now CA $1,832 per person
CA $1,832
per person
Aug 1 - Aug 8
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
10/10 Exceptional! (1 review)
The lake view was beautiful and so was the room

Reviewed on Sep 16, 2025

Highland Lake View Incredible Location!

Highland Lake View Incredible Location!

4 out of 5
Price was CA $1,730, price is now CA $1,701 per person
CA $1,701
per person
Aug 1 - Aug 8
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
9.4/10 Exceptional! (3 reviews)
Very nice property and we had an amazing time!!

Reviewed on Jul 17, 2024

Where to stay in Northeast Missouri

Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
St. Louis Missouri

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton

Ready to book your vacation to Northeast Missouri?

 

Choose your dates

Northeast Missouri Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from Jun 14 to Jun 15
CA $188
CA $220 total
Jun 14 - Jun 15
includes taxes & fees
8.8/10 Excellent! (2,025 reviews)
"Great location and friendly staff!"

Reviewed on Jun 12, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $133 per night from Jul 12 to Jul 13
CA $133
CA $155 total
Jul 12 - Jul 13
includes taxes & fees
9/10 Wonderful! (3,258 reviews)
"We were impressed from check-in to check-out. The staff was very friendly and helpful, the room was clean and quiet, the breakfast was great. Will definitely stay there again and will recommend it."

Reviewed on Jun 11, 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Jun 16 to Jun 17
CA $145
CA $190 total
Jun 16 - Jun 17
includes taxes & fees
8.4/10 Very Good! (2,231 reviews)
"The whole place was dirty and not maintained. There was no breakfast. Staff was rude and not at all helpful. Way overpriced. Stay literally anywhere else."

Reviewed on Jun 11, 2026

Hollywood Casino & Hotel St. Louis
See all 2,898 properties in Northeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Northeast Missouri

Busch Stadium

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
St. Louis Zoo

St. Louis Zoo

4.5/5(7 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo
City Museum

City Museum

4.5/5(6 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

City Museum

What to do in Northeast Missouri

LEGOLAND® Discovery Center Kansas City

LEGOLAND® Discovery Center Kansas City

CA $33
per adult
LEGOLAND® Discovery Center Kansas City
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

CA $48
per adult
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
See all activities in Northeast Missouri

Frequently asked questions

Can I cancel my flight booking to Northeast Missouri due to COVID-19?
Our Customer Service Portal has important information about canceling or changing your flight due to COVID-19. Before you reserve a seat, it's wise to read the terms and conditions of your airfare too.
What's the best way to find cheap flights to Northeast Missouri that have flexible change policies?
It's as easy as 1-2-3 with Expedia. Step 1: Type in your travel dates and hit "Search." Next, check "No change fee" under the "Flexible change policies" subheading on the top left of your screen. Step 3. Score a cheap and flexible flight to Northeast Missouri.
What are some of the general tips for travelers to Northeast Missouri during the COVID-19 outbreak?
As a result of the COVID-19 pandemic, traveling now comes with a few more challenges than usual. Make a note of these worthwhile tips before boarding your flight to Northeast Missouri:
  • Research if any travel restrictions apply to your origin and destination before committing to a flight. Also check if there are any conditions you'll have to follow on arrival, such as taking a COVID-19 test.
  • Requirements state you must wear a face mask at the airport, including at screening checkpoints. You should be prepared to adjust your mask for identification purposes when asked by a TSA employee.
  • To minimize the risk of cross-contamination, position your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA employee.
  • TSA is now permitting passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on luggage. This will need to be removed from your bag to be screened.
  • Place any personal items (like your phone and wallet) in your carry-on rather than a bin to reduce handling during screening.
  • If you're bringing food through the screening checkpoint, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA officer will need to touch your carry-on bag or food container for closer inspection.

Which airlines fly to Northeast Missouri?
Arrange your fare with American Airlines and start working on your Northeast Missouri must-do list. This popular airline offers 898 flights per month to Lambert-St. Louis Intl. Airport (STL), a main gateway.
How can I find cheap tickets to Northeast Missouri?
You'll always find a terrific deal with Expedia, but our "flexible dates" search function makes it that much easier. Enter your preferred travel date, then tick the flexible dates box above to see the cheapest prices for nearby days. was the lowest price for a flight to Northeast Missouri in the last seven days.
How much is a flight to Northeast Missouri?
If you were journeying one way from (), you could've snapped up a low-cost fare for just in the last seven days. Return flights to Northeast Missouri ranged from to over the same period.
What are the most popular airports to fly into in Northeast Missouri?
The principal gateway to Northeast Missouri, roughly 5579 flights service Lambert-St. Louis Intl. Airport (STL) each month. Look for a top deal, reserve your seat and get set to soak up the best of this renowned region.
When is the cheapest time to fly to Northeast Missouri?
If you'd prefer to spend your vacation dollars on having fun in Northeast Missouri rather than on your flight there, depart early in the week. The most cost-effective day to fly is generally Tuesday, with Monday coming in second. With many folks traveling over the weekend, Saturday typically has the costliest airfares.
How much is a plane ticket to Northeast Missouri?
In the last seven days, plane fares to Northeast Missouri varied between and . Prices tend to rise over time, so find a bargain today.
Which airlines with flights to Northeast Missouri employ COVID-19 cleanliness policies?
In order to limit contact between travelers and cabin crew during the COVID-19 outbreak, most airlines have taken social distancing and other measures to the skies. Just some of these are:
  • Southwest Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.