Title: Top Hotels in New Madrid County | Expedia.ca [Vacation Rentals in New Madrid County](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Vacation-Rental-Destinations)[New Madrid County Car Rentals](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Car-Rental-Destinations)[New Madrid County Vacations](https://expedia.ca/New-Madrid-County.d553248635976433157.Destination-Travel-Guides) ![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman # Search New Madrid County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in New Madrid County ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Sikeston [](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Jan 11 - Jan 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 12 - Jan 13](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for New Madrid County hotels ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $125 CA $144 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (462 reviews) "Very clean and super friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine CA $139 CA $157 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,003 reviews) "A great stay in every aspect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gertrude CA $88 CA $100 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/a2f06e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/0c032f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/d0c3544f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "Very clean, very friendly! We will be staying again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth CA $104 CA $120 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,008 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $93 CA $106 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (728 reviews) "Clean room and easy access to room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne CA $77 CA $88 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very good (734 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (48 reviews) "THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AHMAD CA $141 CA $159 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/e6403655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/ef46b494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) Marston 8.0/10 Very good (43 reviews) "Great hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dmitry CA $78 CA $89 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (445 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney CA $129 CA $147 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/97dfc357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/55187aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) Sikeston 6.8/10 (579 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Misty CA $83 CA $94 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.2/10 Wonderful (11 reviews) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott CA $158 CA $179 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/5bb06af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/825a993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/f23217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/6099e00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) Marston 6.0/10 (116 reviews) "Had a great time loved it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shyianne CA $77 CA $87 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-f34c7d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1912x0y4-0511a328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1907x0y6-58887435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1905x0y7-6be09486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Malden Airport Inn [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) Malden 7.0/10 Good (68 reviews) "Clean room, quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7a78d337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very good (284 reviews) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen CA $123 CA $140 total includes taxes & fees Jan 16 - Jan 17 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (121 reviews) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $74 CA $88 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1060h720x0y199-6f809fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h1439x0y1-2bafdfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/18e1eee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h809x0y1-d7340261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room! [](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) New Madrid 10/10 Exceptional (1 review) "The host was very quick to respond and so great to work with for on our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica S. CA $278 CA $477 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/aab8c593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/f956f55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/ee2b7138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Cozy Apartment with large windows and sunlight. [](https://www.expedia.ca/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/e0fa396b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handicap Room](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/6128b6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) Tiptonville 7.0/10 Good (464 reviews) "I had a decent stay near Reelfoot Lake — definitely about a 2-star hotel. I appreciated that the room had tile floors instead of carpet, though they weren’t very clean or well-kept. The door barely locked, which was a bit concerning, and there were dogs barking throughout the night, making it hard to rest. That said, I was thankful to find a place at the last minute, and it served its purpose for a quick overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison CA $72 CA $83 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/89000000/88740000/88733200/88733109/e386e384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88740000/88733200/88733109/9753dccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88740000/88733200/88733109/5565d8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/89000000/88740000/88733200/88733109/54819309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dave's shallow lake at reelfoot lake lodging cabin 15 [](https://www.expedia.ca/Tiptonville-Hotels-Daves-Shallow-Lake-At-Reelfoot-Lake-Lodging.h88733109.Hotel-Information) Tiptonville 10/10 Exceptional (2 reviews) "We had a wonderful trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terri G. CA $278 CA $465 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Tiptonville-Hotels-Daves-Shallow-Lake-At-Reelfoot-Lake-Lodging.h88733109.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=553248635976433157&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ## Top New Madrid County Hotel Reviews ![Super 8 By Wyndham Marston](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d663210_y.jpg) ### Super 8 By Wyndham Marston 10/10 Excellent "Good coffe and parking " [](https://expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Clean and comfy room. Great staff" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Room was very spacious, clean and well equipped Breakfast was good, staff was great and they had a great little mini store " [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg) ### The Farmstead Hotel 10/10 Excellent "Staff was amazing" [](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![Hampton Inn By Hilton Dexter](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2_y.jpg) ### Hampton Inn By Hilton Dexter 10/10 Excellent "Friendly check in. " [](https://expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 10/10 Excellent "Staff promptly fixed a problem, room smelled very clean." [](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![TownePlace Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3_y.jpg) ### TownePlace Suites by Marriott Sikeston 10/10 Excellent "Beautiful new hotel. Great service. The construction must have been rushed or corners were cut. The wallpaper in the bathroom was already bubbling. We had a great stay. " [](https://expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "The room was very nice and the bathroom was very clean. Everything was very nice and the breakfast was good. We were very pleased with everything. I recommend it highly." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Nice man and good hotel" [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in New Madrid County - [Marston Hotels ](https://expedia.ca/Marston-Hotels.d55824.Travel-Guide-Hotels) - [New Madrid Hotels ](https://expedia.ca/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Matthews Hotels ](https://expedia.ca/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Lilbourn Hotels ](https://expedia.ca/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels) - [Morehouse Hotels ](https://expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [Gideon Hotels ](https://expedia.ca/Gideon-Hotels.d3000349377.Travel-Guide-Hotels) - [Tallapoosa Hotels ](https://expedia.ca/Tallapoosa-Hotels.d553248634983263480.Travel-Guide-Hotels) - [Howardville Hotels ](https://expedia.ca/Howardville-Hotels.d553248634983363505.Travel-Guide-Hotels) - [Risco Hotels ](https://expedia.ca/Risco-Hotels.d3000349516.Travel-Guide-Hotels) - [Canalou Hotels ](https://expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Marston Community Center ](https://expedia.ca/Marston-Community-Center-Hotels.0-l553248622945532712-0.Travel-Guide-Filter-Hotels) - [Hotels near New Madrid Historical Museum ](https://expedia.ca/New-Madrid-Historical-Museum-Hotels.0-l553248621532655748-0.Travel-Guide-Filter-Hotels) - [Hotels near River Ridge Winery ](https://expedia.ca/River-Ridge-Winery-Hotels.0-l553248621532655749-0.Travel-Guide-Filter-Hotels) - [Hotels near Hunter-Dawson State Historic Site ](https://expedia.ca/Hunter-Dawson-State-Historic-Site-Hotels.0-l553248621532655794-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River ](https://expedia.ca/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake ](https://expedia.ca/Reelfoot-Lake-Hotels.0-l553248635976195913-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake State Park ](https://expedia.ca/Reelfoot-Lake-State-Park-Hotels.0-l553248621532655205-0.Travel-Guide-Filter-Hotels) - [Hotels near Century Casino Caruthersville ](https://expedia.ca/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels) - [Hotels near Sikeston Depot Museum ](https://expedia.ca/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels) - [Hotels near Missouri National Guard Armory ](https://expedia.ca/Missouri-National-Guard-Armory-Hotels.0-l553248635976285533-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in New Madrid County - [Vacation Homes in New Madrid County ](https://expedia.ca/New-Madrid-County-Private-Vacation-Homes.d553248635976433157-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Lodges in New Madrid County ](https://expedia.ca/New-Madrid-County-Lodges.d553248635976433157-aaLodges.Travel-Guide-Accommodation) - [Motels in New Madrid County ](https://expedia.ca/New-Madrid-County-Motels.d553248635976433157-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in New Madrid County ](https://expedia.ca/New-Madrid-County-Cabins.d553248635976433157-aaCabins.Travel-Guide-Accommodation) - [Cottages in New Madrid County ](https://expedia.ca/New-Madrid-County-Cottages.d553248635976433157-aaCottages.Travel-Guide-Accommodation) - [Apartments in New Madrid County ](https://expedia.ca/New-Madrid-County-Apartments.d553248635976433157-aaApartments.Travel-Guide-Accommodation) - [RV Parks in New Madrid County ](https://expedia.ca/New-Madrid-County-RV-Parks.d553248635976433157-aaRVParks.Travel-Guide-Accommodation) ### Explore more hotels - [Hampton Inn Sikeston ](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) - [Fairfield Inn & Suites by Marriott Sikeston ](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) - [New Orleans Inn Portageville ](https://expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) - [Holiday Inn Express & Suites Sikeston Southwest by IHG ](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) - [Super 8 By Wyndham Marston ](https://expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) - [TownePlace Suites by Marriott Sikeston ](https://expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) - [Travel Inn ](https://expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) - [Drury Inn & Suites Sikeston, MO ](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) - [The Farmstead Hotel ](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) - [Best Western Plus Sikeston ](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) [See a list of all hotels in New Madrid County](https://expedia.ca/All-New-Madrid-County-Hotels.d553248635976433157.Travel-Guide-City-All-Hotels) ### More ways to book - 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