Title: Top Hotels in New Madrid County | Expedia.ca [Vacation Rentals in New Madrid County](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Vacation-Rental-Destinations)[New Madrid County Car Rentals](https://expedia.ca/Destinations-In-New-Madrid-County.d553248635976433157.Car-Rental-Destinations)[New Madrid County Vacations](https://expedia.ca/New-Madrid-County.d553248635976433157.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search New Madrid County Hotels ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in New Madrid County Family friendly [](https://www.expedia.ca/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-11-12&d1=2025-11-12&endDate=2025-11-14&d2=2025-11-14&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-11-12&d1=2025-11-12&endDate=2025-11-14&d2=2025-11-14&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-11-12&d1=2025-11-12&endDate=2025-11-14&d2=2025-11-14&amenities=PETS) ## Check prices for these dates Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2025-10-29&endDate=2025-10-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976433157&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in New Madrid County ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1001) "Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $131 CA $151 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8df39481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1001) "Wonderful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carrie CA $107 CA $123 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1015) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine CA $117 CA $134 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (413) "Clean room, nice staff. Would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robbin CA $136 CA $154 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1001) "A great stay in every aspect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gertrude CA $88 CA $100 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (700) "Stayed one night. Good rate for the Hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $84 CA $96 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/06367e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville Portageville 8.0/10 Very good (712) "Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger CA $81 CA $88 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (558) "The room was good a/c kept it cold " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $83 CA $94 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.2/10 Wonderful (28) "Very clean and comfortable room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roxanne CA $141 CA $159 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d663210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking (Mobility, Roll-in Shower)](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/a7ce909b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston Marston 7.8/10 Good (33) "Todo excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Lirra Diaz CA $93 CA $106 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (434) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen CA $141 CA $159 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite Sikeston 6.8/10 (112) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $75 CA $89 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/501c540f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/a3f1cfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/f23217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/825a993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn Marston 5.8/10 (112) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $79 CA $91 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/235e013f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5be64f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/d534aac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (274) "Love Everything " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shonta' CA $123 CA $141 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston Sikeston 8.4/10 Very good (5) "I loved all of what this property had to offer " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian CA $169 CA $191 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-e5745fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1907x0y6-58887435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/c623404d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/68a43d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Malden Airport Inn Malden 7.0/10 Good (62) "Awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna CA $62 CA $75 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h1439x0y1-2bafdfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h719x0y1-5e759738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/44b354ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1050h1619x0y1-13beb152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room! New Madrid CA $223 CA $414 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/f956f55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/6045fc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/aab8c593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Cozy Apartment with large windows and sunlight. Sikeston [](https://www.expedia.ca/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) ![Handicap Room](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/755237c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/e0fa396b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/60633b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn Tiptonville 7.2/10 Good (455) "Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla CA $85 CA $98 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/96df576d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/48099d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/3c043a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/33bcdf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great location just across the street from Reelfoot Lake close to boat ramps Hornbeak 9.8/10 Exceptional (70) "The stay was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George H. CA $139 CA $250 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=553248635976433157&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ## Top New Madrid County Hotel Reviews ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Great service " [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Everything was up to par. Enjoyed our stay. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Enjoyed the evening meal. Children enjoyed the hotdogs and nachos. Everything was great!" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg) ### The Farmstead Hotel 10/10 Excellent "Very new and clean. Service was outstanding! Softest bed I’ve ever slept in." [](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "okay" [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Best Western Plus Sikeston](//images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "All good here" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](//images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "The room was clean and the property was well maintained. The breakfast had a waffle maker as well as bagels and pastry. Too bad they don't provide liquid coffee creamer instead of powder. It was a decent stay for the price." [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](//images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Holiday Inn Express & Suites Sikeston Southwest by IHG](//images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da_y.jpg) ### Holiday Inn Express & Suites Sikeston Southwest by IHG 10/10 Excellent "Well maintained property. We’ll stop again should we need to." [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in New Madrid County - [Marston Hotels](https://expedia.ca/Marston-Hotels.d55824.Travel-Guide-Hotels) - [New Madrid Hotels](https://expedia.ca/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Matthews Hotels](https://expedia.ca/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Morehouse Hotels](https://expedia.ca/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [Gideon Hotels](https://expedia.ca/Gideon-Hotels.d3000349377.Travel-Guide-Hotels) - [Lilbourn Hotels](https://expedia.ca/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels) - [Tallapoosa Hotels](https://expedia.ca/Tallapoosa-Hotels.d553248634983263480.Travel-Guide-Hotels) - [Howardville Hotels](https://expedia.ca/Howardville-Hotels.d553248634983363505.Travel-Guide-Hotels) - [Risco Hotels](https://expedia.ca/Risco-Hotels.d3000349516.Travel-Guide-Hotels) - [Canalou Hotels](https://expedia.ca/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near New Madrid Historical Museum](https://expedia.ca/New-Madrid-Historical-Museum-Hotels.0-l553248621532655748-0.Travel-Guide-Filter-Hotels) - [Hotels near Marston Community Center](https://expedia.ca/Marston-Community-Center-Hotels.0-l553248622945532712-0.Travel-Guide-Filter-Hotels) - [Hotels near Hunter-Dawson State Historic Site](https://expedia.ca/Hunter-Dawson-State-Historic-Site-Hotels.0-l553248621532655794-0.Travel-Guide-Filter-Hotels) - [Hotels near River Ridge Winery](https://expedia.ca/River-Ridge-Winery-Hotels.0-l553248621532655749-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River](https://expedia.ca/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake](https://expedia.ca/Reelfoot-Lake-Hotels.0-l553248635976195913-0.Travel-Guide-Filter-Hotels) - [Hotels near Reelfoot Lake State Park](https://expedia.ca/Reelfoot-Lake-State-Park-Hotels.0-l553248621532655205-0.Travel-Guide-Filter-Hotels) - [Hotels near Century Casino Caruthersville](https://expedia.ca/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels) - [Hotels near Kennett Country Club](https://expedia.ca/Kennett-Country-Club-Hotels.0-l6245780-0.Travel-Guide-Filter-Hotels) - [Hotels near Hemingway Center](https://expedia.ca/Hemingway-Center-Hotels.0-l553248621532648021-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in New Madrid County - [Vacation Homes in New Madrid County](https://expedia.ca/New-Madrid-County-Private-Vacation-Homes.d553248635976433157-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Lodges in New Madrid County](https://expedia.ca/New-Madrid-County-Lodges.d553248635976433157-aaLodges.Travel-Guide-Accommodation) - [Motels in New Madrid County](https://expedia.ca/New-Madrid-County-Motels.d553248635976433157-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in New Madrid County](https://expedia.ca/New-Madrid-County-Cabins.d553248635976433157-aaCabins.Travel-Guide-Accommodation) - [Cottages in New Madrid County](https://expedia.ca/New-Madrid-County-Cottages.d553248635976433157-aaCottages.Travel-Guide-Accommodation) - [Apartments in New Madrid County](https://expedia.ca/New-Madrid-County-Apartments.d553248635976433157-aaApartments.Travel-Guide-Accommodation) - [RV Parks in New Madrid County](https://expedia.ca/New-Madrid-County-RV-Parks.d553248635976433157-aaRVParks.Travel-Guide-Accommodation) ### Explore more hotels - [Hampton Inn Sikeston](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) - [Fairfield Inn & Suites by Marriott Sikeston](https://expedia.ca/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) - [New Orleans Inn Portageville](https://expedia.ca/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) - [Holiday Inn Express & Suites Sikeston Southwest by IHG](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) - [Super 8 By Wyndham Marston](https://expedia.ca/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) - [TownePlace Suites by Marriott Sikeston](https://expedia.ca/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) - [Travel Inn](https://expedia.ca/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) - [The Farmstead Hotel](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) - [Drury Inn & Suites Sikeston, MO](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) - [Drury Inn & Suites Hayti Caruthersville](https://expedia.ca/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information) [See a list of all hotels in New Madrid County](https://expedia.ca/All-New-Madrid-County-Hotels.d553248635976433157.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in New Madrid County on Expedia.com](https://www.expedia.com/Destinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Golf Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Golf-Hotel.0-0-d178304-tGolfHotel.Hotel-Filter-Destinations) - 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