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Cayo Santa Maria Vacations

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Top flight + hotel deals in Cayo Santa Maria

Nobu Hotel at Caesars Palace
Sheraton Gateway Los Angeles Hotel
Hollywood Historic Hotel
Kimpton La Peer Hotel
Hotel Normandie

Best lodging options near Cayo Santa Maria

Grand Memories Santa Maria - All Inclusive
Grand Memories Santa Maria - All Inclusive
3.5 out of 5
Municipio Caibarien, Cayo Santa Maria, Villa Clara
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2.8/5 (78 reviews)

"beautiful beach and good food at the buffet despite long queues to get it. Room needs to be totally refurbished to be compared to an European 5 stars resort! However, the staying was pleasant!"…"

Reviewed on Mar. 28, 2020

Grand Memories Santa Maria - All Inclusive
Villa Gaviota Cayo Coco
Villa Gaviota Cayo Coco
Ciego de Avila, Cayo Santa Maria
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Villa Gaviota Cayo Coco
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
3.5 out of 5
Cayo Santa Maria, Cayo Santa Maria, Villa Clara
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3.3/5 (47 reviews)

"The beach is beautiful, the food and drink are good and better than other hotels that I stayed before, but property conditions are not good, dirty walls, bad repairs, etc... rooms services are not good neither. Room phone does not work. Pools are for children (only 3 feets of deep at any place) and ..."…"

Reviewed on Oct. 28, 2019

Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Pre-Packaged Vacations & All Inclusive Resorts in Cayo Santa Maria

Have the quiet and magnificent escape you dream of in the stress-free paradise of Cayo Santa Maria, Cuba. This destination is one where you finally get to lay back, relax, and enjoy memorable time basking in the sun.

Cayo Santa Maria is a beautiful tropical island forming part of the famous King’s Gardens archipelago, located north of Cuba’s main island. This small paradise measures only 13 kilometers long by a few kilometers wide and is connected to the mainland by a scenic 48-km causeway. Its popularity is mainly due to its luscious white beaches stretching along most of its northern coastline and its luxurious resorts.

Declared a Biosphere Reserve by UNESCO

The wonderful fauna and flora preserved in Cayo Santa Maria Wildlife Refuge allows lucky travellers the chance to admire Cuba’s pristine beauty and richness. Stroll along immaculate beaches and hike wondrous trails until you reach its charming secluded cove for the perfect spot to admire Cuba’s amazing sunrise if you get up early enough.

Enjoyment for Everyone

With its array of things to do and see, Cayo Santa Maria vacations are certain to leave you relaxed, delighted, and entertained, no matter your age and preferences. These wonderful activities include:

  • The opportunity to swim with dolphins and see dolphins or sea lion shows at Cayo Santa Maria’s impressive and modern dolphin aquarium—one of the largest in Latin America
  • Take part in many water sports and tours
  • Enjoy a massage at a luxurious spa
  • Visit interesting Cuban villages
  • Have fun exploring its lively nightlife at local bars, pubs, and discotheques

Cayo Santa Maria Packages

How can one resist the island’s charm? Benefit from’s great search tool, which is guaranteed to provide you with the best deals on Cayo Santa Maria all-inclusive offers! We take pride in simplifying your life.

Frequently asked questions

How much does a Cayo Santa Maria vacation package cost?
From as little as CA $502, you can customize your Cayo Santa Maria package the way you want. Simply bundle hotels, flights and rental cars and be rewarded with discounts.
If I'm not able to travel, can I cancel my Cayo Santa Maria vacation package?
It is possible to cancel your Cayo Santa Maria booking if your travel plans have changed. Whether you’ll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Head to our Customer Service Portal for more information.
How do I get a cheap travel package to Cayo Santa Maria?
Our Cayo Santa Maria vacation packages promise plenty of savings for the savvy wanderer. How does as much as C$590 sound? That’s what you could save if you combine your hotel, flights and tours into a neat and tidy package. But cheap deals are only the start of your next epic adventure. When you book with Expedia, and you’ll have over 400 air carriers and 321,000 hotel options around the globe to choose from. No matter your budget, there’s a vacation package here just for you.
When is the best time of year to visit Cayo Santa Maria?
If you love the atmosphere of peak season, head to Cayo Santa Maria in August, April, March. If you’re chasing a calmer vibe, December, November, October will suit you better. Don’t want to spend a fortune? You might want to avoid July, when things like airfares and hotels go up in price. October is generally when you’ll score the best deals.
How far in advance should I book my Cayo Santa Maria vacation?
Savvy travelers always book early. Airlines usually release flight tickets around a year ahead of departure, and this is when you can land some rock-bottom prices. Just been told you need to take some vacation time next week? No problem! Expedia are never short of fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Cayo Santa Maria travel package include?
That depends on what kind of getaway you have in the works. Cayo Santa Maria vacation deals can include hotels, flights and car rentals. You can mix and match to find the package that suits you. You can also add on activities and experiences after you’ve booked to get even bigger discounts.
What should I know before booking a Cayo Santa Maria travel package?
So many places to visit, so many things to experience. With a travel package, you can cross more of them off your list. Bundle your flights, rental cars and hotels and get ready to save.
Does Expedia offer Book Now, Pay Later Cayo Santa Maria vacation packages?
Thanks to our partnership with online lender Affirm, vacationers booking via Expedia can now pay off their journey in small installments that won’t hurt your wallet. Book Now, Pay Later and begin your dream getaway today!
Can I choose my airline with a Cayo Santa Maria Expedia vacation package?
You can. We have more than 550 airline partners all over the world, so choose the carrier that best fits your travel needs.