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Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
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Dec 4 - Dec 6
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Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Advance

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is CA $133
CA $151 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
"Breakfast was good."
United States
J
The price is CA $112
CA $121 total
includes taxes & fees
Nov 8 - Nov 9
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

3. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (652 reviews)
"Great hotel, clean spacious room, good breakfast choice"
United Kingdom
Deborah
The price is CA $140
CA $159 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Sikeston
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

4. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
United States
Chris
The price is CA $139
CA $156 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

5. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
The price is CA $112
CA $118 total
includes taxes & fees
Nov 29 - Nov 30
Drury Inn & Suites Jackson MO
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

6. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is CA $141
CA $161 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

7. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
"The stay was pleasant from start to finish. Extremely nice staff, good breakfast and convenient parking. The location was also great!"
United States
Celeste
The price is CA $101
CA $113 total
includes taxes & fees
Nov 9 - Nov 10
Pear Tree Inn Cape Girardeau West
A living room with a blue wall, a fireplace, a sofa, and a chair.

8. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is CA $147
CA $160 total
includes taxes & fees
Dec 3 - Dec 4
EC Reed's Mercantile and Hotel
Property amenity

9. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (29 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
United States
Mark
The price is CA $148
CA $168 total
includes taxes & fees
Nov 15 - Nov 16
TownePlace Suites by Marriott Sikeston
A modern retail area with a display of local items and snacks.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is CA $119
CA $136 total
includes taxes & fees
Nov 12 - Nov 13
Tru By Hilton Cape Girardeau
A buffet with various food items, including omelets and baked goods, served in metal containers.

11. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (520 reviews)
"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."
United States
Melissa
The price is CA $133
CA $151 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express & Suites Sikeston Southwest by IHG
A hotel room with a large bed, a desk, a chair, a small table, and a window with a view of the outdoors.

12. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
"Great property"
United States
John
The price is CA $149
CA $168 total
includes taxes & fees
Nov 16 - Nov 17
The Riverview
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

13. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (858 reviews)
"Everything was lovely. Great room, breakfast, pool, and staff."
United States
Vonnie
The price is CA $137
CA $154 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Cape Girardeau I 55 East
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

14. Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (288 reviews)
"The place was okay for a night"
United States
Herman
The price is CA $71
CA $81 total
includes taxes & fees
Dec 4 - Dec 5
Econo Lodge Dexter
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

15. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, spacious suite, enjoyable kick back and breakfast!"
United States
Mary
The price is CA $126
CA $142 total
includes taxes & fees
Nov 13 - Nov 14
Drury Inn & Suites Cape Girardeau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

16. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (240 reviews)
"Great hotel…!!"
United States
Carlos
The price is CA $141
CA $159 total
includes taxes & fees
Nov 19 - Nov 20
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

17. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
United States
Jeff
The price is CA $105
CA $114 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Suites Jackson-Cape Girardeau
A modern hotel lobby with a central dining area, a minibar, and a view of the outdoors.

18. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.6 out of 10, Exceptional, (82 reviews)
"This place is Brand new and really great!"
United States
Bryan
The price is CA $137
CA $155 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn By Hilton Dexter
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

19. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (819 reviews)
"Clean rooms, nice staff"
United States
Dayanita
The price is CA $83
CA $94 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Cape Girardeau North
A diner with booth seating, a checkered floor, and a counter with a cash register.

20. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (424 reviews)
"Staff was very friendly"
United States
Steven
The price is CA $123
CA $140 total
includes taxes & fees
Nov 15 - Nov 16
Travelodge by Wyndham Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top reviews in Advance

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau

10/10 Excellent

Friendly staff, clean room. Great food. Highly recommend this hotel.
Canada
Sareh
Reviewed August 9, 2026
Drury Plaza Hotel Cape Girardeau Conference Center

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