5 Stars Hotels in South Loop, Chicago from CA $241

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about South Loop

South of downtown Chicago, this neighborhood features cultural activities, sports and convention centers and a great dining and nightlife scene.

South Loop which includes a high-rise building and a city

Top South Loop Hotel Reviews

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Frequently asked questions

What are the best 5-star hotels in South Loop?
The St. Regis Chicago is among the most popular picks around the Central Chicago neighbourhood of South Loop according to Expedia customers. The Langham, Chicago and Trump International Hotel & Tower Chicago are other 5-star hotels in this area that rank highest with travellers.
How much does it cost to stay in a 5-star hotel in South Loop?
The amount you pay for a 5-star hotel in South Loop can vary depending on when you decide to travel and how long you plan to stay, among other factors. Use our price per night filter and other search tools to score the best rate on an indulgent stay.

  • Search for the lowest price per night from CA $241

What makes a hotel 5 stars in South Loop?
From fine dining restaurants and 24-hour fitness centres to swimming pools and deluxe bedding, the 5-star experience in South Loop is all about comfort and indulgence. But it takes more than just top-notch perks to earn a 5-star rating. Hotels also have to offer superior guest services like massage treatments, on-site laundry and 24-hour concierge services.