Title: Southeast Missouri Vacation Rentals from CA $175: Short-Term Rentals for 2025 | Expedia.ca

 

[Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:
Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.
It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.
This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 
#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bill Dillard

# Southeast Missouri Vacation Rentals

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## Check prices for these dates

In two weeks

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-12-12&endDate=2025-12-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-01-23&endDate=2026-01-25&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Vacation Rentals in Southeast Missouri

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113880000/113879200/113879109/df663fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/114000000/113880000/113879200/113879109/f41c0202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/114000000/113880000/113879200/113879109/08a25916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/114000000/113880000/113879200/113879109/e64cef9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

New Offenburg

10/10

Exceptional

(4)

"Relaxing setting between Farmington and St Genevieve. Both towns are rich in history and have small town charm. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tim M.

CA $212

CA $423 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Peaceful-3-Bedroom-House-With-WiFi-And-AC-In-Lovely-New-Offenburg.h113879109.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/283ae672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/c213727d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/8cdda898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/67000000/66890000/66883200/66883194/59b1b1e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Micro house cabin located near Silver Mines Recreation Area.

Fredericktown

10/10

Exceptional

(76)

"This was my second visit and am planning to return again someday. Very quiet and cozy. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

eric y.

[](https://www.expedia.ca/Fredericktown-Hotels-Micro-House-Cabin-Located-Near-Silver-Mines-Recreation-Area.h66883194.Hotel-Information)

![1 bedroom, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/86d734a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/81907571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/f03e39eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/08a1bdfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Modern Loft In Wine Country!

Ste. Genevieve

10/10

Exceptional

(270)

"Loved our stay here! Thoughtful amenities on a beautiful property. Great communication with host. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elsie H.

CA $209

CA $253 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Beautiful-Modern-Loft-In-Wine-Country.h23139432.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/93328db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w525h683x259y0-930fe938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, Hulu, streaming services](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-c8068718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-84bc4b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "Little Brick House on Main (1865)”

Ste. Genevieve

10/10

Exceptional

(62)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lettitia B.

CA $168

CA $224 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1020h683x4y0-fa4cb879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/67a4ab9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, books, video library](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1024h455x0y114-14a42b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104130000/104123500/104123411/w1014h683x5y0-c3534739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Collier Cabin in Pine Hollow ~ Eminence, MO

Birch Tree

9.6/10

Exceptional

(25)

"Really awesome!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melinda R.

[](https://www.expedia.ca/Birch-Tree-Hotels-Collier-Cabin-In-Pine-Hollow-Eminence.h104123411.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/92000000/91610000/91604100/91604045/92213a4a_edited_27e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/92000000/91610000/91604100/91604045/b26f87a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/92000000/91610000/91604100/91604045/a2104458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91610000/91604100/91604045/988779b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Cabin on the edge of town only 1/2 mile from Current River !

Van Buren

9.4/10

Exceptional

(8)

"We stay here a couple times a year. In the summer to float the river and in the winter to be near relatives for the holidays. Great experience in both seasons. Very close to the river, gas, and grocery. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shelie L.

[](https://www.expedia.ca/Van-Buren-Hotels-Cozy-Cabin-On-The-Edge-Of-Town-Only-12-Mile-From-Current-River.h91604045.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/79000000/78390000/78382600/78382544/54dccacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, free WiFi](https://images.trvl-media.com/lodging/79000000/78390000/78382600/78382544/16fef5e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/79000000/78390000/78382600/78382544/c6fa156f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/79000000/78390000/78382600/78382544/f713c817.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Couples Retreat with hot tub (cabin2)

Leadwood

9.6/10

Exceptional

(21)

"it was a nice cozy stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alvaro

CA $52

CA $222 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Park-Hills-Hotels-Couples-Retreat-With-Hot-Tub.h78382544.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/55527a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/f4fbd89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/c5155680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/ed5a3737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Twisted Sassafras Treehouse

Cape Girardeau

10/10

Exceptional

(26)

"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary C.

CA $291

CA $425 total

includes taxes & fees

Dec 8 - Dec 9

[](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/68000000/67140000/67135900/67135817/9f1b48ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/68000000/67140000/67135900/67135817/w1170h1560x0y486-7708b776.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/68000000/67140000/67135900/67135817/5aaf2aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/68000000/67140000/67135900/67135817/w1170h1560x0y486-717b3c8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Doves Nest Guest House<br> Tranquil & Relaxing

Ste. Genevieve

10/10

Exceptional

(54)

"Great place. Close to everything you need for a great stay in St. Genevieve. Easy check and great host."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Justin S.

CA $228

CA $378 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Doves-Nest-Guest-Housebr-Tranquil-Relaxing.h67135817.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/570788ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/04c500be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/b46c570c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59960000/59955800/59955709/eed3215e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### #ContemplationCabin on the Jacks Fork River!

Summersville

10/10

Exceptional

(70)

"Wanted an escape before starting back to school for the fall and this was exactly what we got. Easy communication with owner and got quick response. Beautiful and quiet property! Great spot on the river!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin A.

CA $353

CA $478 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Contemplationcabin-On-The-Jacks-Fork-River.h59955709.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/17fd79b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/e90509fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/d8535e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/89b52c31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau

9.6/10

Exceptional

(44)

"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jordan S.

CA $116

CA $195 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Artistic-Indoor-Swing-2-Blocks-To-Downtown.h71736900.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/w1525h2000x0y0-3cce06ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/c7fde387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/9c2435e1_edited_6d62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111500000/111491800/111491747/d4816ff1_edited_0721.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Springside Cottage in beautiful Eminence. Great outdoor space - NEW Hot tub!

Eminence

9.2/10

Wonderful

(15)

"Amazing cottage! Great location for a float trip or to explore the Ozark sites. Check-in was easy, host was very accommodating, house was clean and cozy. We will definitely be back for a peaceful getaway! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Betsy S.

[](https://www.expedia.ca/Eminence-Hotels-Springside-Cottage-In-Pleasant-Eminence-Great-Outdoor-Space-Large-Yard.h111491747.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/0cb5c163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-36b84305.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h569x0y57-57bff386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y56-1ec5791d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Your home away from home in downtown, historic Farmington!

Farmington

10/10

Exceptional

(36)

"Beautiful piece of property. Would stay here again and again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary N.

[](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/b002a425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/66471bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/c93cba87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/6a5a3c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cape Girardeau

10/10

Exceptional

(27)

"Great property and a super host! He was super helpful and always willing to help with any questions we had. Would definitely rent here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark M.

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/701aec9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/f0863f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/1198f66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/b16ce2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Poplar Bluff

8.6/10

Excellent

(8)

"The house was very clean and nicely decorated. The huge TV in the living room was a plus and the mattress was very comfortable. We would stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brian

CA $141

CA $358 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Charming-2-Bedroom-House-With-2-KING-BEDS-In-Pleasant-Poplar-Bluff.h110066526.Hotel-Information)

![1 bedroom, WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/120000000/119910000/119900400/119900352/a8a73634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119910000/119900400/119900352/7663a33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/120000000/119910000/119900400/119900352/06775a68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119910000/119900400/119900352/c5868f87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Secret Sycamore– Private Stargazing Glamping Tent with Fire Pit & Open Skies

Bunker

10/10

Exceptional

(2)

"They were very friendly and our kids and dogs loved it. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wesley

CA $141

CA $181 total

includes taxes & fees

Dec 4 - Dec 5

[](https://www.expedia.ca/Bunker-Hotels-Secret-Sycamore-Private-Stargazing-Glamping-Tent-With-Fire-Pit-Open-Skies.h119900352.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/70000000/69410000/69400800/69400733/024a6098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/70000000/69410000/69400800/69400733/11f1f1ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69410000/69400800/69400733/3e9a2e0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69410000/69400800/69400733/ed5a9064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Triple H Properties

Eminence

8.6/10

Excellent

(27)

"Worked out great for friends to stay for a float trip weekend. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kat S.

[](https://www.expedia.ca/Eminence-Hotels-Triple-H-Properties.h69400733.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/7282fe58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/b169a39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books, video library](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/2c03a8ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/6b0c4075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Get Away Acres 1/2 mile off highway 60 extra sanitized

Ellsinore

10/10

Exceptional

(95)

"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

CA $155

CA $192 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Ellsinore-Hotels-Get-Away-Acres-12-Mile-Off-Highway-60-Extra-Sanitized.h18787495.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/77000000/76710000/76703700/76703700/722fd5ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76710000/76703700/76703700/w1115h745x0y0-ce8cd160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76710000/76703700/76703700/w1115h745x7y0-93f305fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/77000000/76710000/76703700/76703700/w1116h743x0y4-df905179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chasen Summer! 1/2 Mile from Current River!

Van Buren

9.4/10

Exceptional

(40)

"My Family and I have stayed at this house "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Benjamin D.

[](https://www.expedia.ca/Van-Buren-Hotels-Chasen-Summer-12-Mile-From-Current-River.h76703700.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/85b01dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/da6816e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/b5551dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/87e0f8d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mountain View at Pickle & Perk

Ironton

10/10

Exceptional

(15)

"Very cute place in beautiful area. Easy check-in, clean home, and comfy bed. The coffee shop below was really good with a beautiful patio. Location was perfect to access Elephant Rocks, Johnson Shut-ins, and Taum Sauk Mountain parks. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amber S.

CA $202

CA $285 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Ironton-Hotels-Mountain-View-At-Pickle-Perk.h105789927.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11&regionId=6058763&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=COTTAGE)

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=APARTMENT)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=VACATION_HOME)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=CONDO)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Southeast+Missouri%2C+Missouri%2C+United+States+of+America&regionId=6058763&latLong=37.223648%2C-90.426492&adults=2&startDate=2026-02-24&d1=2026-02-24&endDate=2026-02-27&d2=2026-02-27&lodging=VILLA)

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## Top Southeast Missouri Hotel Reviews

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Clean room. Clean well stocked bathroom. Nice big bathroom. Very courteous check in attendent. And sweet lady serving breakfast. "

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Breakfast and super Kickoff was AWESOME? love this hotel!!!"

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

10/10 Excellent

"I did not stay for breakfast, but I did have a hot dinner that was excellent. I will recommend and stay at Drury Inn's the next time I travel."

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Drury Inn & Suites Poplar Bluff](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164_y.jpg)

### Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Love having the extra food at night, let's us relax and not have to go anywhere."

[](https://expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"Great room, close to downtown, awesome food options in the venue as well. Really nice views of the river."

[](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Holiday Inn Poplar Bluff by IHG](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7_y.jpg)

### Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"Very spacious suite, awesome staff! "

[](https://expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the location so that was a plus! They had quite a lot of items for breakfast, so I was surprised about that for a Days Inn. Only thing I didn't like was lack of parking, but overall, I would definitely stay here again if I come back to the area."

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg)

### Hampton Inn Sikeston

10/10 Excellent

"The place was nice and clean"

[](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks. "

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

## Find out more about Southeast Missouri

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Southeast Missouri. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.  
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.  

## Explore a world of travel with Expedia

-   Trending destinations on Expedia.ca
-   All accommodation types in Southeast Missouri

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-   [Vacation Homes in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Private-Vacation-Homes.d6058763-aaPrivateVacationHomes.Travel-Guide-Accommodation)
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-   [Maui Vacation Rentals](https://expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)

General

-   [Visit Downtown St. Louis](https://expedia.ca/St-Louis-Downtown-St-Louis.dx800136)
-   [Visit Downtown Kansas City](https://expedia.ca/Kansas-City-Downtown-Kansas-City.dx6058828)
-   [Visit Parkville](https://expedia.ca/Parkville.dx9973)
-   [Visit Whidbey Island](https://expedia.ca/Whidbey-Island.dx500782)

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