Title: Book The Best Hotels in East Cape Girardeau, IL for 2026 from CA $89 - Fully Refundable Options - Expedia.ca [Vacation Rentals in East Cape Girardeau](https://expedia.ca/East-Cape-Girardeau-Vacation-Rentals.d553248634983574328.Travel-Guide-VacationRentals)[East Cape Girardeau Car Rentals](https://expedia.ca/Car-Rentals-In-East-Cape-Girardeau.d553248634983574328.Car-Rental-Guide)[East Cape Girardeau Vacation Packages](https://expedia.ca/East-Cape-Girardeau.d553248634983574328.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in East Cape Girardeau Family friendly [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=PETS) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=HOT_TUB) Cabin [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=CABIN) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=APARTMENT) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=WATER_PARK) ## Check prices for these dates Tonight [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 19 - Jan 20](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248634983574328&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for East Cape Girardeau hotels ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/7794c781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, Non Smoking, Garden View](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fd5c34e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a236a8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) Cape Girardeau 10/10 Exceptional (19 reviews) "My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $216 CA $244 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/f7d52bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/c3df8884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) Cape Girardeau 8.2/10 Very good (891 reviews) "Room was clean and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $109 CA $130 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (151 reviews) "Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $122 CA $138 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (105 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $124 CA $142 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/051de21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/b20a49e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (787 reviews) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina CA $147 CA $166 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c66d7d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (691 reviews) "The room was clean and nice. The breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kalani CA $83 CA $94 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/006e0795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,003 reviews) "Staff great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave (2 Rooms, Tub)](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,003 reviews) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin CA $125 CA $141 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (481 reviews) "Very nice hotel within walking distance to many good restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky CA $174 CA $197 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (491 reviews) " Excellent stay. Will come again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joydeep CA $129 CA $146 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature)](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,003 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex CA $127 CA $143 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,009 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $125 CA $141 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking (NRF)](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/2b1b1011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Cape Girardeau 6.0/10 (208 reviews) "Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $77 CA $89 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (688 reviews) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip CA $111 CA $120 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/b5f01af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,003 reviews) "Suited our purpose for overnight on a road trip " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $115 CA $122 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/3bfecde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, Multiple Beds](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/c3d8fe66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/5e9ee6eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/e7ab16b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel 7 Inn Anna [](https://www.expedia.ca/Anna-Hotels-Hotel-7-Inn-Anna.h8295732.Hotel-Information) Anna 6.6/10 (217 reviews) "A very pleasant and quiet spot to spend the night." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Philip CA $111 CA $128 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Anna-Hotels-Hotel-7-Inn-Anna.h8295732.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/59c49f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f29b08e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) Cape Girardeau 9.0/10 Wonderful (1,000 reviews) "Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $97 CA $111 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/0ac4753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very good (740 reviews) "Clean and comfortable every time. This is a “go to” hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqulyn CA $111 CA $120 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Accessible, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/46ce3d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/ef0f7e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (430 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $93 CA $101 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=553248634983574328&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels.d553248634983574328.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels.d553248634983574328.Travel-Guide-Hotels) ## More cheap stays in East Cape Girardeau ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO CA $97 CA $111 total Jan 22 - Jan 23 includes taxes & fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO CA $109 CA $130 total Feb 8 - Feb 9 includes taxes & fees 8/10 Very Good! (890 reviews) [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Cape Girardeau 433 CAPE WEST CROSSINGS Cape Girardeau MO CA $122 CA $138 total Jan 25 - Jan 26 includes taxes & fees 9.4/10 Exceptional! (149 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr Cape Girardeau MO CA $124 CA $142 total Jan 27 - Jan 28 includes taxes & fees 9.4/10 Exceptional! (105 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO CA $127 CA $143 total Jan 25 - Jan 26 includes taxes & fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=40113&PinnedHotelID=40113&HadPinnedHotel=true®ionId=553248634983574328) 8.8/10 Excellent! (1,002 reviews) [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ## Hotels in East Cape Girardeau with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-East-Cape-Girardeau-Hotels.s40-0-d553248634983574328.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.ca/3Star-East-Cape-Girardeau-Hotels.s30-0-d553248634983574328.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 19 properties [](https://expedia.ca/2Star-East-Cape-Girardeau-Hotels.s20-0-d553248634983574328.Travel-Guide-Filter-Hotels) ## Recent reviews of East Cape Girardeau hotels ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 5/5 Excellent "Room and staff were great. Fantastic breakfast!" A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center Posted 2 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent "Room was spotless, staff was SO kind. 5 day trip, stayed in 4 different hotels & this one was BY FAR the nicest. Breakfast was fabulous. 10 out of 10 recommend!! " A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 4 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 5/5 Excellent "Loved the happy hour, and pet friendly & shower." A verified traveller stayed at Drury Inn & Suites Cape Girardeau Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 5/5 Excellent "Very nice room. There was a little noise from other rooms or perhaps from the hallways. The breakfast was very good. " A verified traveller stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 5/5 Excellent "Yes" A verified traveller stayed at Fairfield Inn & Suites by Marriott Cape Girardeau Posted 6 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Hampton Inn Cape Girardeau I 55 East](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d_y.jpg) ### Hampton Inn Cape Girardeau I 55 East 5/5 Excellent "Tonja at the front desk was wonderful! Please compliment her. We decided to leave at 5 am and she had coffee and fruit for us. Most importantly- she was so pleasant and handled her work so professionally. " A verified traveller stayed at Hampton Inn Cape Girardeau I 55 East Posted 7 days ago [](https://expedia.ca/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 5/5 Excellent "Nice place" A verified traveller stayed at Courtyard by Marriott Cape Girardeau Downtown Posted 8 days ago [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Coffee pot empty in breakfast area " A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 9 days ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 5/5 Excellent "Room was spotless. The whole hotel was clean and the staff were very kind. " A verified traveller stayed at The Riverview Posted 9 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in East Cape Girardeau? ### What are some of the best vacation home rentals that East Cape Girardeau has to offer? ### If I need to cancel my hotel reservation in East Cape Girardeau, will I receive a refund? ### How is it staying in East Cape Girardeau? ### What should I see while I'm in East Cape Girardeau? ### What's the weather like in East Cape Girardeau? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Pomona ](https://www.expedia.ca/5Star-Pomona-Hotels.s50-0-d553248635592817265.Travel-Guide-Filter-Hotels) - [Apartments in Alto Pass ](https://www.expedia.ca/Alto-Pass-Apartments.d73449-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Alto Pass ](https://www.expedia.ca/Alto-Pass-Cabins.d73449-aaCabins.Travel-Guide-Accommodation) - 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