A coastal town with clear turquoise waters, rocky shores, and white buildings.

Find Spa Hotels in Anna, IL from CA $162

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Check availability on Anna Spa Hotels

Tonight
Sep 24 - Sep 25
Tomorrow
Sep 25 - Sep 26
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Anna hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
CA $142
CA $162 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
View all properties

Choose what matters most at spa hotels in Anna

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Anna Hotel Reviews

Hampton Inn Carbondale

Hampton Inn Carbondale

10/10 Excellent
"It was just for one night so we picked a less expensive option, and WOW! We were so pleasantly surprised at the big, beautiful room! A great place to stay."
Michelle 1-night trip
Posted 9 hours ago
Hampton Inn Carbondale
Best Western Marion Hotel

Best Western Marion Hotel

10/10 Excellent
"Clean, friendly staff and nice breakfast. Would definitely stay again."
Susan 1-night trip
Posted 2 days ago
Best Western Marion Hotel
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Great hotel, had zero issues and staff was lovely"
Kegan 3-night trip
Posted 3 days ago
Drury Inn & Suites Cape Girardeau

Frequently asked questions

Looking for a spa hotel in Anna?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the local architecture and restaurants in Anna—your day trip starts here. Enjoy the historical sites and natural parks during your vacation. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your weekend away.
What's there to see and do in Anna?
Enjoy all that Anna has to offer and visit Shawnee National Forest, Anna City Park, and King Neptune Memorial. If you have a bit of extra time while you're in the area, you might want to check out Giant City State Park and Blue Sky Vineyards.
What is a Anna spa hotel?
Spa hotels in Anna provide lodging and have a full on-site spa offering services including massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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