Title: Book the Best Anna SPA Resorts from CA $156 - Spa Hotels in Anna, IL | Expedia.ca

 

[Hotels in Anna](https://expedia.ca/Anna-Hotels.d6406.Travel-Guide-Hotels)[Vacation Rentals in Anna](https://expedia.ca/Anna-Vacation-Rentals.d6406.Travel-Guide-VacationRentals)[Anna Car Rentals](https://expedia.ca/Car-Rentals-In-Anna.d6406.Car-Rental-Guide)[Anna Vacation Packages](https://expedia.ca/Anna.d6406.Destination-Travel-Guides)

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# Find Spa Hotels in Anna, IL from CA $156

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## Check availability on Anna Spa Hotels

Tonight

[Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2025-11-02&endDate=2025-11-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6406&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Anna Spa Hotels

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

9.4/10

Exceptional

(1001)

"Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Penny

CA $139

CA $156 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16&regionId=6406&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Anna Hotel Reviews

![Drury Inn & Suites Marion](//images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg)

### Drury Inn & Suites Marion

10/10 Excellent

"The breakfast was good, and in the evening having coffee and a soft drink fountain available was very nice. My only suggestion would be to provide a more firm pillow."

[](https://expedia.ca/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Beds were comfortable and good breakfast"

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Best Western Marion Hotel](//images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d_y.jpg)

### Best Western Marion Hotel

10/10 Excellent

"One of the best variety breakfasts I've seen. Room was clean. Room was missing easy chair. Strong disinfectant smell when arrived. Bed was good."

[](https://expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information)

## Frequently asked questions

### Looking for a spa hotel in Anna?

> Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the local architecture and restaurants in Anna—your day trip starts here. Enjoy the historical sites and natural parks during your vacation. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your weekend away.

### What's there to see and do in Anna?

> Enjoy all that Anna has to offer and visit Shawnee National Forest, Anna City Park, and King Neptune Memorial. If you have a bit of extra time while you're in the area, you might want to check out Giant City State Park and Blue Sky Vineyards.

### What is a Anna spa hotel?

> Spa hotels in Anna provide lodging and have a full on-site spa offering services including massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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