East Cape Girardeau Vacation Rentals

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Our top choices for East Cape Girardeau vacation rentals

10.0 out of 10, Exceptional, (102 reviews)
"Great place so peaceful and relaxing "
United States
Paul D.
The price is CA $185
CA $389 total
includes taxes & fees
Feb 26 - Feb 27
Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, (21 reviews)
"The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants"
United States
Marsha G.
The price is CA $154
CA $250 total
includes taxes & fees
Feb 25 - Feb 26
Peaceful secluded cabin located near Horseshoe Lake

Vacation Home in Cape Girardeau

Little Blue Cottage on Spanish
8.4 out of 10, Very good, (50 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
The price is CA $111
CA $138 total
includes taxes & fees
Feb 26 - Feb 27
Little Blue Cottage on Spanish
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
The price is CA $212
CA $397 total
includes taxes & fees
Feb 26 - Feb 27
Charming Secluded Getaway Cabin within minutes of amenities
10.0 out of 10, Exceptional, (102 reviews)
"Would love to rent it again, was cozy clean private and perfect Thanks Mary for taking the extra mile and helping with turning of heat"
United States
Ravi Sankar Reddy K.
The price is CA $241
CA $469 total
includes taxes & fees
Feb 26 - Feb 27
Contemporary Glamping with Native American Appeal!
10.0 out of 10, Exceptional, (3 reviews)
"Kayla was quick to answer any questions. Her description of the place is very accurate. Beautifully remodeled. Spacious. Comfortable beds. We rented because it's the perfect location if you want to explore Giant City and Ferne Clyffe. We didn't have time this time but there are numerous parks and biking trails nearby. I highly recommend it."
United States
Ronda H.
The price is CA $108
CA $202 total
includes taxes & fees
Feb 26 - Feb 27
Cozy and Updated Farmhouse with King Suite

Cabin in Olive Branch

The Rested Duck Mallard Room
9.4 out of 10, Exceptional, (28 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is CA $154
CA $192 total
includes taxes & fees
Mar 1 - Mar 2
The Rested Duck Mallard Room
10.0 out of 10, Exceptional, (151 reviews)
"Such a great place and location"
United States
Tracy H.
The price is CA $205
CA $337 total
includes taxes & fees
Feb 26 - Feb 27
Serenity South -- Gardens, River-Views, and Refreshing Space
8.8 out of 10, Excellent, (39 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
The price is CA $185
CA $298 total
includes taxes & fees
Feb 26 - Feb 27
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
9.8 out of 10, Exceptional, (35 reviews)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is CA $154
CA $192 total
includes taxes & fees
Mar 1 - Mar 2
Cozy cabins on beautiful Horseshoe Lake

Cabin in Cape Girardeau

The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (31 reviews)
"This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!"
United States
Eric S.
The price is CA $295
CA $431 total
includes taxes & fees
Mar 9 - Mar 10
The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is CA $205
CA $250 total
includes taxes & fees
Feb 25 - Feb 26
Relax in the country at Countryside Villas! - Villa A
10.0 out of 10, Exceptional, (5 reviews)
"great place. wonderful host."
United States
Carla m.
The price is CA $159
CA $357 total
includes taxes & fees
Feb 25 - Feb 26
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is CA $274
CA $429 total
includes taxes & fees
Mar 11 - Mar 12
Gorgeous 1856 Log Cabin, Completely Renovated
10.0 out of 10, Exceptional, (5 reviews)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
The price is CA $322
CA $576 total
includes taxes & fees
Feb 26 - Feb 27
Magical Victorian near hiking / wine trail
9.6 out of 10, Exceptional, (8 reviews)
"Nice place, great times"
United States
Jace W.
The price is CA $368
CA $596 total
includes taxes & fees
Feb 25 - Feb 26
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Mobile Home in Jackson

The Cottage, Rusted Route Farms
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is CA $171
CA $271 total
includes taxes & fees
Feb 26 - Feb 27
The Cottage, Rusted Route Farms
The price is CA $684
CA $833 total
includes taxes & fees
Feb 25 - Feb 26
Building at Cape Girardeau Regional Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top East Cape Girardeau Hotel Reviews

Find out more about East Cape Girardeau

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with East Cape Girardeau. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in East Cape Girardeau?

Yes, there are vacation rentals near well known sights in East Cape Girardeau, or you can select a more secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that East Cape Girardeau has to offer?

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau: This vacation home rental near East Cape Girardeau is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in East Cape Girardeau?

Explore the area and family-friendly sights such as Cape Splash Family Aquatic Center, or get out into nature at a spot like Cape Rock Park. Isle Casino Cape Girardeau and Southeast Missouri State University are a couple of places you'll find in the larger area.

What’s a vacation rental in East Cape Girardeau like?

A vacation rental is a private property you can book for a couple of days or more in East Cape Girardeau. Vacation rentals offer extras like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from shared hotel elevators and busy front desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for a small group gathering.