Title: Book the Best PET FRIENDLY Hotels in Cairo, IL from CA $92 - Cairo Dog-Friendly Hotels | Expedia.ca [Hotels in Cairo](https://expedia.ca/Cairo-Hotels.d6626.Travel-Guide-Hotels)[Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Cairo Car Rentals](https://expedia.ca/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.ca/Cairo.d6626.Destination-Travel-Guides) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Pet-friendly Hotels in Cairo, IL from CA $92 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cairo Pet-friendly Hotels Tonight [Dec 20 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-20&endDate=2025-12-21&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-21&endDate=2025-12-22&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Cairo pet-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/96f1c1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) Cairo 6.6/10 (273) "Break fast was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Uma CA $101 CA $112 total includes taxes & fees Jan 17 - Jan 18, 2026 [](https://www.expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.6/10 (612) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $86 CA $95 total includes taxes & fees Jan 17 - Jan 18, 2026 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/a51b6a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/7ebce143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/fe5a3b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Country Stay: Modern Home Near Paducah [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information) Cunningham CA $167 CA $399 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (104) "Middle of nowhere hotel was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $83 CA $92 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36690000/36688500/36688411/7b4967a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/37000000/36690000/36688500/36688411/74a9ce52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36690000/36688500/36688411/90-b5148e0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/37000000/36690000/36688500/36688411/180-920b85ce_edited_ee1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Cabin Retreat [](https://www.expedia.ca/Tamms-Hotels-Beautiful-Cabin-Retreat.h36688411.Hotel-Information) tamms 8.2/10 Very good (41) "This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy V. CA $200 CA $326 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tamms-Hotels-Beautiful-Cabin-Retreat.h36688411.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/c1fa9596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, internet, bed sheets](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/79b6441c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/8482f63b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/42d2c51f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Country Stay: Modern Home Near Paducah [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) Cunningham CA $149 CA $393 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-03&endDate=2026-01-04®ionId=6626&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Cairo Hotel Reviews ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg) ### Quality Inn Cairo I-57 10/10 Excellent "Break fast was excellent " [](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Quality Inn Charleston - Sikeston](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb_y.jpg) ### Quality Inn Charleston - Sikeston 10/10 Excellent "The staff was very friendly and accommodating " [](https://expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Eagle Inn Charleston](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a_y.jpg) ### Eagle Inn Charleston 10/10 Excellent "Furniture missing knobs. No chair!!??? No coffee!!?? No breakfast. Nice location. Nice staff!! " [](https://expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ## Frequently asked questions ### What's the best pet-friendly place to stay in Cairo? ### What's the best time of year to travel to Cairo with my pet? ### What is there to see and do with your pet in Cairo? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in West Vienna ](https://www.expedia.ca/3Star-West-Vienna-Hotels.s30-0-d553248635975864465.Travel-Guide-Filter-Hotels) - [Farmstay in Anna ](https://www.expedia.ca/Anna-Agritourism.d6406-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Anna ](https://www.expedia.ca/Anna-Bed-And-Breakfast.d6406-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chalets in Anna ](https://www.expedia.ca/Anna-Chalets.d6406-aaChalets.Travel-Guide-Accommodation) - [Guest Houses in Anna ](https://www.expedia.ca/Anna-Guest-Houses.d6406-aaGuestHouses.Travel-Guide-Accommodation) - [Hotels & Resorts for Couples in Anna ](https://www.expedia.ca/Anna-Hotels-Couples-Resorts-Hotels.0-0-d6406-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - 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