Title: Cairo Motel: Browse Cheap Motels in Cairo 2025 | Expedia.ca [Hotels in Cairo](https://expedia.ca/Cairo-Hotels.d6626.Travel-Guide-Hotels)[Vacation Rentals in Cairo](https://expedia.ca/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.ca/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Cairo Car Rentals](https://expedia.ca/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.ca/Cairo.d6626.Destination-Travel-Guides) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Motels in Cairo from CA $84 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6626&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Cairo Motels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO Charleston 6.6/10 (610) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $76 CA $84 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/2b61a8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/d436dcb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston Charleston 6.8/10 (102) "Middle of nowhere hotel was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $85 CA $95 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6626&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AA_BF_PROMO_6626) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Motels.d6626-aaMotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Motels.d6626-aaMotels.Travel-Guide-Accommodation) ## Top Cairo Hotel Reviews ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](https://images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg) ### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 10/10 Excellent "Second time staying. Still have all positives to say! Wonderfully quiet place for a get away weekend. Well stocked kitchen and items in refrigerator to use for making breakfast included. Details have been thought about for guests. Host is very responsive! " [](https://expedia.ca/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information) ![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. 10/10 Excellent "Very nice property. Loved the outdoor space and we would love to stay again! The owners are chef kiss. " [](https://expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![The Rested Duck Mallard Room](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg) ### The Rested Duck Mallard Room 10/10 Excellent "It was fine. It was fairly clean and the bed was comfortable. No where to put anything down in the bathroom. " [](https://expedia.ca/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) ![Charming cottage overlooking Lake Acre](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087_y.jpg) ### Charming cottage overlooking Lake Acre 10/10 Excellent "Exactly as advertised, very clean and beautiful location!" [](https://expedia.ca/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg) ### Peaceful secluded cabin located near Horseshoe Lake 10/10 Excellent "The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants" [](https://expedia.ca/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg) ### Quality Inn Cairo I-57 10/10 Excellent "Break fast was excellent " [](https://expedia.ca/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![La Center Motel](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg) ### La Center Motel 10/10 Excellent "The place was very clean" [](https://expedia.ca/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Beautiful newly renovated farm house overlooking 5 acre lake. ****New Rates ***](https://images.trvl-media.com/lodging/69000000/68040000/68038600/68038535/956cd1de_y.jpg) ### Beautiful newly renovated farm house overlooking 5 acre lake. \*\*\*\*New Rates \*\*\* 10/10 Excellent "This place was absolutely beautiful! The home is wonderfully restored and shows the history of the property. The lake was excellent for kayaking and fishing. We saw deer near the lake in the evenings. The home is also well stocked with everything you will need for your stay." [](https://expedia.ca/Dongola-Hotels-Beautiful-Newly-Renovated-Farm-House-Overlooking-5-Acre-Lake-New-Rates.h68038535.Hotel-Information) ## Find out more about Cairo ## Cairo Motels information | Number of reviews | 709 | | --- | --- | | Accommodation | 2 Motels | | Lowest Price | CA $84 | | Highest Price | CA $95 | ## Frequently asked questions ### What is the nightly rate for a motel in Cairo? > You can find a great deal from CA $84 on Cairo motels with Expedia. Typically, prices are higher during popular times – like weekends and holidays – while staying midweek is often cheaper. To find the best nightly rates on Cairo motels, try to be flexible with travel dates, and sort search results by price from low to high. ### Is it better to stay in a Cairo motel or hotel? > Motels and Hotels have different perks. When you stay at a motel, you're likely to find free parking and an outdoor pool. Staying overnight at a motel, can be handy when requiring easy road access. You'll often have access to your room from outside, and directly from the parking lot. Hotels generally have room access from inside the building. Motels are also often less expensive than hotels. 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