South Carolina Lowcountry Vacation Rentals

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Our top choices for South Carolina Lowcountry vacation rentals

The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (21 reviews)
"Great property "
United States
Caleb C.
The price is CA $144
CA $301 total
includes taxes & fees
Apr 5 - Apr 6
The Grey Pearl on Port Royal's Battery Creek

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (55 reviews)
"Relaxing and comfortable stay"
United States
cheryl j.
The price is CA $139
CA $402 total
includes taxes & fees
Apr 20 - Apr 21
Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (31 reviews)
"We so loved our stay! Our stay was AMAZING! Great location, great views, and the downtown area is very close and easy to get to. Cannot wait to rebook your place!! "
United States
Glenn G.
The price is CA $150
CA $310 total
includes taxes & fees
Apr 6 - Apr 7
Mariners' Nautical Nest on Port Royal's Battery Creek

Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
9.8 out of 10, Exceptional, (100 reviews)
"Great stay! Private, cozy, and quiet with a great view of the water and marsh."
United States
Jad
The price is CA $132
CA $286 total
includes taxes & fees
Apr 4 - Apr 5
Gorgeous Waterfront Battery Creek Retreat

'wright by the Beach': Hilton Head Condo w/ Perks

'wright by the Beach': Hilton Head Condo w/ Perks
3.0 star property
Mid Island
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our stay. We loved the ocean theme at the apartment. Very clean rooms. Kids enjoyed swimming in the indoor pool, parents enjoyed hot tub and sauna especially on rainy days. They have indoor and outdoor pools. We liked walking on the boardwalk to the beach. We highly recommend this place and would love to return there again. "
United States
Victor
The price is CA $96
CA $381 total
includes taxes & fees
Mar 31 - Apr 1
'wright by the Beach': Hilton Head Condo w/ Perks

Ocean Front & pool view. Hunting Island pass included

Ocean Front & pool view. Hunting Island pass included
Beachwalk
9.8 out of 10, Exceptional, (67 reviews)
"great stay at a great location "
United States
Greg B.
The price is CA $276
CA $558 total
includes taxes & fees
Apr 1 - Apr 2
Ocean Front & pool view. Hunting Island pass included

All Inn on Edisto - Cozy Studio Condo Close to Everything

All Inn on Edisto - Cozy Studio Condo Close to Everything
Edisto Beach
9.8 out of 10, Exceptional, (156 reviews)
"Excellent cute little studio apartment. Thoroughly enjoyed coming back and resting after a long day of work."
United States
Cabell G.
The price is CA $138
CA $272 total
includes taxes & fees
Mar 31 - Apr 1
All Inn on Edisto - Cozy Studio Condo Close to Everything

Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (45 reviews)
"Clean, cozy, and close to Parris Island!"
United States
Jeremy G.
The price is CA $188
CA $355 total
includes taxes & fees
Mar 31 - Apr 1
Charming Coastal Casa on Beaufort's Battery Creek

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
WALTERBORO
10.0 out of 10, Exceptional, (16 reviews)
"Clean room great location, beautiful stay!"
United States
Morgan K.
The price is CA $276
CA $377 total
includes taxes & fees
Mar 31 - Apr 1
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE
Old Town Bluffton
9.4 out of 10, Exceptional, (133 reviews)
"Property was in a great location and everything was clean."
United States
Miranda
The price is CA $244
CA $490 total
includes taxes & fees
Apr 26 - Apr 27
Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue
Walterboro
9.6 out of 10, Exceptional, (13 reviews)
"Clean room Beautiful Highly recommend "
United States
Taylor P.
The price is CA $276
CA $377 total
includes taxes & fees
Mar 31 - Apr 1
Osprey Cottage Suite 3717-A - part of the Eden at Gracefield Event Venue

SeaClusion-Oceanview, Mini split AC, Beach Chairs

SeaClusion-Oceanview, Mini split AC, Beach Chairs
South End
9.6 out of 10, Exceptional, (61 reviews)
"Location cleanliness cozy the beach 3min walk its a great spot"
United States
kenneth
The price is CA $116
CA $365 total
includes taxes & fees
Apr 1 - Apr 2
SeaClusion-Oceanview, Mini split AC, Beach Chairs

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown
Sea Pines
10.0 out of 10, Exceptional, (82 reviews)
"Great stay"
United States
jeremy h.
The price is CA $204
CA $513 total
includes taxes & fees
Apr 12 - Apr 13
Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Newly Renovated, Spacious 2bd Apartment w. Parking!

Newly Renovated, Spacious 2bd Apartment w. Parking!
Historic District
9.8 out of 10, Exceptional, (16 reviews)
"Love the condo. Perfect location. Excellent communication. 5 stars "
United States
Debby
The price is CA $217
CA $571 total
includes taxes & fees
Mar 31 - Apr 1
Newly Renovated, Spacious 2bd Apartment w. Parking!

King Suite at The Emerald, Spa Bathroom w. Robes!

King Suite at The Emerald, Spa Bathroom w. Robes!
Historic District
9.6 out of 10, Exceptional, (33 reviews)
"Wonderful stay, had everything we needed and loves the location. We will be staying here again!"
United States
Leah R.
The price is CA $144
CA $283 total
includes taxes & fees
Apr 1 - Apr 2
King Suite at The Emerald, Spa Bathroom w. Robes!

Castaways King Villa on Beach, Free Bikes!

Castaways King Villa on Beach, Free Bikes!
South End
10.0 out of 10, Exceptional, (99 reviews)
"The property was great for our needs, close to the beach, restaurants and biking trails. Owners were very easy to work with and very accommodating!"
United States
Kristin
Castaways King Villa on Beach, Free Bikes!

Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (92 reviews)
"Great place for our quick weekend get away! "
United States
Ronda J.
The price is CA $125
CA $257 total
includes taxes & fees
Apr 19 - Apr 20
Cozy Edisto Condo-Close to the Beach!

Disney's Hilton Head Island Resort

Disney's Hilton Head Island Resort
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (128 reviews)
"While the rooms are overdue a refurbishment, this place is a wondeful resort. "
United States
Chad
Disney's Hilton Head Island Resort

Charming Renovated Villa in Oceanfront Community w/ Pool and Direct Beach Access

Charming Renovated Villa in Oceanfront Community w/ Pool and Direct Beach Access
South End
9.6 out of 10, Exceptional, (76 reviews)
"Perfect location"
United States
Laura L.
The price is CA $144
CA $438 total
includes taxes & fees
Mar 31 - Apr 1
Charming Renovated Villa in Oceanfront Community w/ Pool and Direct Beach Access

Bluffton Retreat, Pet Friendly

Bluffton Retreat, Pet Friendly
Bluffton
10.0 out of 10, Exceptional, (21 reviews)
"Host was very responsive to our needs."
United States
Margie S.
The price is CA $271
CA $481 total
includes taxes & fees
Apr 6 - Apr 7
Bluffton Retreat, Pet Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Lowcountry Hotel Reviews

Find out more about South Carolina Lowcountry

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with South Carolina Lowcountry. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.