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Find Luxury Hotels in South Main, Houston

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Check availability on South Main Luxury Hotels

Tonight
Aug 7 - Aug 8
Tomorrow
Aug 8 - Aug 9
This weekend
Aug 8 - Aug 10
Next weekend
Aug 15 - Aug 17

Top South Main Luxury Hotels

Top South Main Hotel Reviews

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

10/10 Excellent
" Great place "
Cassandra 1-night trip
Posted 17 hours ago
Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in South Main?
Use Expedia to help you arrange a flight to Houston William Hobby Airport (HOU) airport or Houston, TX (EFD-Ellington Field) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that South Main has to offer. South Main has some interesting things to see and do including NRG Park, so you might want to take in the local sights during your visit.
How many luxury hotels should I expect to find in South Main?
Lie in the lap of luxury during your getaway to South Main in one of Expedia's 6 luxury hotels.
What's the best time to vacation in South Main?
The hottest months are usually August and July with an average temperature of 83°F,
  • Coldest months: January, February, December, and November
  • Driest months: February, March, December, and January
  • Rainiest months: May, September, August, and April
What's there to see and do in South Main?
Experience all that South Main has to offer when you visit NRG Park, NRG Stadium, and Houston Zoo. If you have extra time while you're in the area, you might want to see Toyota Center and Daikin Park.
How can I get around South Main?
It's easier to get around town comfortably when you know your options. Head over to Fannin South Station for metro transit.