Title: Book the Best Texas Medical Center LUXURY Hotels - Upscale Hotels in Texas Medical Center, Houston | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Texas Medical Center, Houston - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Texas Medical Center Luxury Hotels Tonight [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-05&endDate=2025-12-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 6 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-06&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Texas Medical Center Luxury Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/5cc6610b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/87753400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/c3718846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/75d213df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott Medical Center/Museum District Texas Medical Center 9.0/10 Wonderful (1000) "Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elena CA $212 CA $293 total includes taxes & fees Dec 13 - Dec 14 [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/428800/428779/4c06ef00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite | Private kitchen](https://images.trvl-media.com/lodging/1000000/430000/428800/428779/7ec37c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/428800/428779/7becac76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 1 Double Bed with Sofa bed, Accessible, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/1000000/430000/428800/428779/789b748d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites Houston Med Ctr Braeswood Bl Texas Medical Center 5.8/10 (1001) "Great receptionist. Clean room. Perfect location to access Md Anderson. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $101 CA $118 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Houston-Hotels-Extended-Stay-America-Suites-Houston-Med-Ctr-Braeswood-Bl.h428779.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-19&endDate=2025-12-20®ionId=6143504&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Texas Medical Center ### Texas Medical Centerand its attractions for luxury travelers Nestled in the heart of Houston, the Texas Medical Center offers a unique blend of luxury and innovation, perfect for discerning travellers seeking both comfort and convenience. Begin your exploration at the renowned Houston Museum District, where you can indulge in world-class art at the Museum of Fine Arts or enjoy interactive exhibits at the Houston Museum of Natural Science. Just a stone's throw away, the beautiful Hermann Park invites guests to unwind amidst its picturesque gardens, with opportunities for paddle boating on the serene lake or a stroll through the stunning Japanese Garden. For sports enthusiasts, catch a game at NRG Stadium, home to the Houston Texans and a venue for major events, ensuring an adrenaline-filled experience. Families with children will appreciate the nearby Houston Zoo, where they can enjoy a close encounter with wildlife in an expansive, lush setting. After an adventurous day, retreat to one of the luxury hotels in the area, where you can expect plush accommodations, state-of-the-art spa services, and gourmet dining options that cater to your every need. Many of these hotels offer exclusive packages that include private tours of medical institutions, allowing you to experience the pioneering research and care firsthand, all while enjoying the attentive service that ensures you feel pampered throughout your stay. ### Find the best luxury hotels and resorts in Texas Medical Center For those seeking a lavish stay in the heart of Texas Medical Center, these hotels promise an exquisite experience complemented by top amenities and exceptional service. [**InterContinental Houston by IHG**](https://www.expedia.ca/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) - **Why it's great for a luxury retreat:** InterContinental Houston by IHG is a luxury haven, ideally situated in Texas Medical Center with an outstanding guest review rating of 9.2\. This hotel features premium bedding and luxurious bathrobes, providing guests with an elegant stay. The on-site spa and outdoor pool offer perfect spots for relaxation, while the attentive concierge service ensures that all needs are met during your stay. - **Other amenities:** The hotel also boasts a fitness centre that is accessible 24 hours for those looking to stay active. Guests can enjoy the convenience of valet and self-parking options, along with electric car charging stations. The inviting terrace and patio areas provide lovely spaces to unwind, while daily housekeeping guarantees a fresh and clean environment throughout your visit. - **Neighborhood:** Texas Medical Center - **Nearby attractions:** MD Anderson Cancer Center - 1.1 km [**Houston Marriott Medical Center/Museum District**](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) - **Why it's great for a luxury retreat:** Houston Marriott Medical Center/Museum District offers luxury and comfort with an impressive guest review rating of 9.0\. The hotel is adorned with premium bedding and Egyptian cotton sheets, guaranteeing a restful night’s sleep. Guests can enjoy the convenience of valet parking and access to a 24-hour fitness centre, making it an excellent choice for health-conscious travellers. - **Other amenities:** In addition to its luxury offerings, the hotel features a business centre, a restaurant with a diverse menu, and options for early check-in and late check-out. Nearby golf courses provide leisure opportunities, while daily housekeeping and complimentary toiletries add to the comfort of your stay. - **Neighborhood:** Texas Medical Center - **Nearby attractions:** MD Anderson Cancer Center - 0.7 km [**The Westin Houston Medical Center/Museum District**](https://www.expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) - **Why it's great for a luxury retreat:** The Westin Houston Medical Center/Museum District is a luxurious retreat with a guest review rating of 9.0, designed for those who appreciate elegance and comfort. The hotel features premium bedding, bathrobes, and a stylish poolside bar, allowing guests to unwind in style. The exquisite Art Deco design adds a unique touch, making this hotel a great choice for travelers. - **Other amenities:** Beyond its luxurious amenities, guests can take advantage of a rooftop garden and outdoor pool, perfect for relaxation. A 24-hour fitness centre caters to wellness enthusiasts, while the concierge service ensures all guests receive personalised assistance. Additional features include express check-in, electric car charging stations, and a welcoming atmosphere that enhances the overall experience. - **Neighborhood:** Texas Medical Center - **Nearby attractions:** MD Anderson Cancer Center - 0.7 km [**Blossom Hotel Houston**](https://www.expedia.ca/Houston-Hotels-Blossom-Houston-Hotel.h58985846.Hotel-Information) - **Why it's great for a luxury retreat:** Blossom Hotel Houston is a splendid choice for luxury travelers, a remarkable guest review rating of 9.0\. This stylish hotel offers premium bedding, plush bathrobes, and designer toiletries, ensuring a comfortable and indulgent stay. Guests can enjoy the serene outdoor pool area and a full-service spa, perfect for relaxation after a day of exploring. - **Other amenities:** In addition to its luxurious offerings, Blossom Hotel features a 24-hour fitness centre, valet parking, and convenient electric car charging stations. The rooftop terrace provides stunning views of the city, while daily housekeeping keeps the environment pristine. With options for early check-in and late check-out, travelers can enjoy a seamless experience at this exquisite hotel. - **Neighborhood:** Texas Medical Center - **Nearby attractions:** MD Anderson Cancer Center - 1.4 km [**Hilton Houston Plaza/Medical Center**](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) - **Why it's great for a luxury retreat:** Hilton Houston Plaza/Medical Center is a luxurious destination with a solid guest review rating of 8.4, ideal for travellers seeking comfort and service. The hotel features premium bedding and a delightful poolside bar, enhancing the overall experience. Guests can indulge in the on-site restaurant and relax in the outdoor pool, perfect for unwinding after a busy day. - **Other amenities:** Additional amenities include a well-equipped fitness centre, valet and self-parking options, and a terrace for enjoying the surroundings. The hotel also offers convenient in-room facilities like refrigerators and coffee makers, ensuring guests have everything they need for a comfortable stay. - **Neighborhood:** Texas Medical Center - **Nearby attractions:** Hermann Park - 1.1 km, MD Anderson Cancer Center - 0.9 km ## Top Texas Medical Center Hotel Reviews ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Hilton hotel is very beautiful. Front desk man was absolutely polite and nice. Room was big clean and convenient with nice big bathroom and beautiful shower. We had room on top floor with beautiful view on city. Room was with lounge that we liked very much with snacks waters coffee tea and nice breakfast. Thank you hotel ! Very beautiful Christmas decorations as well. " [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Great" [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "Good location, beautiful room and seamless checkin" [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Great room, quiet and elegant. Enjoyed the stay greatly. " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Great service " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Kelvin chatted with me and upgraded our room because we were celebrating a late honeymoon! " [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "The room was very clean. The staff was outstanding!" [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![The Westin Galleria Houston](https://images.trvl-media.com/lodging/1000000/20000/11200/11117/b45a8086_y.jpg) ### The Westin Galleria Houston 10/10 Excellent "Excellent property. Great location next to shopping mall. " [](https://expedia.ca/Houston-Hotels-The-Westin-Galleria-Houston.h11117.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "Really good service, nice location, perfect for long layovers " [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury trip to Texas Medical Center? ### What's the best luxury accommodation in Texas Medical Center? ### What's there to see and do in Texas Medical Center? ### How can I get around Texas Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [3 Star Hotels in Houston Museum District ](https://www.expedia.ca/3Star-Houston-Museum-District-Houston-Hotels.s30-n6164045-0.Travel-Guide-Filter-Hotels) - 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