Title: Santee Vacation Rentals from CA $143: Short-Term Rentals for 2025 | Expedia.ca

  

[Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides)

![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Santee Vacation Rentals

![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)

### 

Change your mind

Book hotels with free cancellation

![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)

### 

Treat yourself

Sign in to save 10% or more on thousands of hotels

[Sign in](https://www.expedia.ca/login)

![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)

### 

Be picky

Search almost a million properties worldwide

## Check prices for these dates

In two weeks

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-24&endDate=2025-10-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In one month

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-07&endDate=2025-11-09&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-12-05&endDate=2025-12-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-01-02&endDate=2026-01-04&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Vacation Rentals in Santee

![Property grounds](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/c4bbcdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/c417e2ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/4d4ed2d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/108000000/107300000/107294400/107294387/bb85ca64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sunsets on Lake Marion

Santee

9.4/10

Exceptional

(13)

"Great place to stay. "

[](https://www.expedia.ca/Santee-Hotels-Sunsets-On-Lake-Marion.h107294387.Hotel-Information)

![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/79beb629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/339c1207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/431d124d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee

10/10

Exceptional

(36)

"Me and my husband had a great stay. Our 2 4 legged furry boys loved the yard so much. Would definitely stay again. "

CA $134

CA $451 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/cf50a6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/d97d64ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/17d2f4e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Vacation Resorts Lake Marion

Santee

9.2/10

Wonderful

(20)

"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."

[](https://www.expedia.ca/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/64e8f8c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/d39bc1a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/a3e119aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/b9db199d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

 

### Lake Marion - Majestic Big Water View!

Santee

10/10

Exceptional

(9)

"Very very nice. Would recommend it for a great stay. "

[](https://www.expedia.ca/Santee-Hotels-Lake-Marion-Majestic-Big-Water-View.h104211609.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/c68f4c0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/d947756b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/25cf21bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/113000000/112150000/112150000/112149977/a7c0a626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2 Bedroom Waterfront Lake Marion Condo

Santee

10/10

Exceptional

(5)

"Everything was beautiful very nice very clean. It was very close to town so if you needed to run into town it was literally 2 minutes down the road. We enjoyed sitting on the porch watching the boats and waves. We fished a lot and made a lot of first time memories. We will never forget this place and this stay. "

[](https://www.expedia.ca/Santee-Hotels-Charming-2-Bedroom-Waterfront-Lake-Marion-Condo.h112149977.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/121000000/120280000/120277200/120277114/2855ff18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120277200/120277114/b3e7b49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120280000/120277200/120277114/2000368c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/121000000/120280000/120277200/120277114/ba956468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful, ground level 3-bedroom condo with pool on scenic Lake Marion

Santee

[](https://www.expedia.ca/Santee-Hotels-Beautiful.h120277114.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/101000000/100750000/100746600/100746556/86920790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100750000/100746600/100746556/dc9de435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/101000000/100750000/100746600/100746556/15f5eaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100750000/100746600/100746556/59ca5206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside vacationing close to golf courses, restaurants and boat rental company!

Santee

9.6/10

Exceptional

(9)

"I had a very nice time and I will definitely come back here"

[](https://www.expedia.ca/Santee-Hotels-Lakeside-Vacationing-Close-To-Golf-Courses.h100746556.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/110000000/109970000/109966200/109966128/866ee785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/110000000/109970000/109966200/109966128/9f1e2bf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/110000000/109970000/109966200/109966128/9be729b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/110000000/109970000/109966200/109966128/d19b82b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi

Santee

[](https://www.expedia.ca/Santee-Hotels-Lakeside-Charming-2-Bedroom-House-In-Lovely-Santee-With-AC.h109966128.Hotel-Information)

![Smart TV, video games, books](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/beb0182f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/w904h683x60y0-352c677c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/e4a179ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107480000/107471600/107471514/4caea529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Santee

10/10

Exceptional

(9)

"Nice place great location "

[](https://www.expedia.ca/Santee-Hotels-Peaceful-Condo-On-Lake-Marion-In-Santee.h107471514.Hotel-Information)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106380000/106375100/106375003/4fc72843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106380000/106375100/106375003/53922228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/107000000/106380000/106375100/106375003/293f63c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/107000000/106380000/106375100/106375003/32d1fd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elloree Vacation Rental ~ 7 Mi to Lake Marion!

Santee

[](https://www.expedia.ca/Santee-Hotels-Elloree-Vacation-Rental-7-Mi-To-Lake-Marion.h106375003.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/495c8e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, coffee/tea maker, blender](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/9d898fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/795ddf27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/dd0654f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bells Marina & Resort

Eutawville

8.6/10

Excellent

(75)

"Had a great stay"

CA $129

CA $143 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/6d916484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/cc0e968f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/c7cb77b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/2111d298.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pet friendly country cottage with large fenced-in yard & horses on property

Holly Hill

10/10

Exceptional

(112)

"My daughter, dog and I were traveling from NC to Tampa, FL. on local roads and Kay's cottage was the best place to stop at! Her cottage has everything you need for a comfortable stay and a perfect fenced in front yard for our dog. We truly enjoyed our stay. Wish we could have stayed longer! "

CA $158

CA $284 total

includes taxes & fees

Oct 20 - Oct 21

[](https://www.expedia.ca/Holly-Hill-Hotels-Come-Relax-In-The-Country.h95993146.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/431a876d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/1c153d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/0949138a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/20000000/20000000/19993600/19993568/32f986d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Summerton

9.6/10

Exceptional

(241)

"The property was nice and had enough room for all 12 of us, 3 boats and all of the fishing equipment. Loved the long dock and the location that’s not far from the big water. We would stay here again when we come back to fish Lake Marion."

[](https://www.expedia.ca/Summerton-Hotels-SANITIZED-Lake-Marion-Lakefront-Sandy-Beach.h19993568.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/49000000/48170000/48166000/48165962/22ca7f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/49000000/48170000/48166000/48165962/c0a48177.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player, table tennis](https://images.trvl-media.com/lodging/49000000/48170000/48166000/48165962/90-0f4f2bdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/49000000/48170000/48166000/48165962/fb0e124b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton

10/10

Exceptional

(154)

"We stay here frequently and have always enjoyed ourselves."

[](https://www.expedia.ca/Sumter-Hotels-Vrbo-Property.h48165962.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118120000/118112500/118112486/6841ceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/119000000/118120000/118112500/118112486/c18de751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/119000000/118120000/118112500/118112486/70879129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/119000000/118120000/118112500/118112486/a626f6f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 2-bedroom Cottage with Deck and Lake View

Vance

[](https://www.expedia.ca/Vance-Hotels-Cozy-2-Bedroom-Cabin-With-Deck-And-Lake-View.h118112486.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/91000000/90710000/90707500/90707426/bfad6db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90710000/90707500/90707426/94e37995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/91000000/90710000/90707500/90707426/e312bca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/91000000/90710000/90707500/90707426/ad268e4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Marion Lakehouse with 180° lake view

Elloree

10/10

Exceptional

(73)

"I would stay here again. Great location."

[](https://www.expedia.ca/Elloree-Hotels-Lake-Marion-Lakehouse.h90707426.Hotel-Information)

![Smart TV, video games, DVD player, books](https://images.trvl-media.com/lodging/34000000/33400000/33395600/33395596/14953324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33400000/33395600/33395596/e2b57e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games, DVD player, books](https://images.trvl-media.com/lodging/34000000/33400000/33395600/33395596/e19944c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33400000/33395600/33395596/57443c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

 

### Beautiful Cottage between Lake Moultrie and Lake Marion

Cross

9.8/10

Exceptional

(143)

"Nice"

[](https://www.expedia.ca/Cross-Hotels-Beautiful-Cottage-Between-Lake-Moultrie-And-Lake-Marion.h33395596.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/3f704424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/7ade87f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/d3a39e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/9998f4d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Resting Spot just off I95. 12 miles west on hwy 6.

Elloree

9.2/10

Wonderful

(19)

"It was very clean and had everything i needed. The host checked in with me while i was there though messages which was nice too. "

CA $145

CA $211 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Elloree-Hotels-Country-Resting-Spot.h107431587.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24420000/24413800/24413799/f6ff7a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24420000/24413800/24413799/2e6333c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/25000000/24420000/24413800/24413799/w4096h2332x0y0-b198d84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24420000/24413800/24413799/cdba1bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

Summerton

9.8/10

Exceptional

(174)

"Plenty of space for a large group. "

[](https://www.expedia.ca/Sumter-Hotels-NEW-Listing-Sanitized-Lake-Marion-Lakefront-Ramp.h24413799.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/16d477ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/a01795f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/c0675035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/d113ea29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Holly Hill

10/10

Exceptional

(4)

"Excellent stay! We will definitely be staying here again! Love this place! "

CA $175

CA $225 total

includes taxes & fees

Oct 15 - Oct 16

[](https://www.expedia.ca/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26&regionId=9953&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)

## Top Santee Hotel Reviews

![Fairfield Inn & Suites by Marriott Santee](//images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg)

### Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

"place was beautiful, workers were nice and courteous and helpful"

[](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information)

![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg)

### Holiday Inn Santee by IHG

10/10 Excellent

"Acting GM was very friendly Happy hour was nice"

[](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information)

![Tru By Hilton Santee](//images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg)

### Tru By Hilton Santee

10/10 Excellent

"Very nice facility "

[](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information)

![Baymont by Wyndham Santee](//images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg)

### Baymont by Wyndham Santee

10/10 Excellent

"Great place to stop on our way to Florida. Places to shop and dine. Hotel is nice and good breakfast. "

[](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)

![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg)

### Travelodge by Wyndham Santee

10/10 Excellent

"The counter tops and appliances needed cleaning, they were greasy. Otherwise the room was okay."

[](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information)

![Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](//images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a_y.jpg)

### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10/10 Excellent

"Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. "

[](https://expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information)

![Hampton Inn Santee-I-95](//images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg)

### Hampton Inn Santee-I-95

10/10 Excellent

"We had a nice and courteous and friendly. Bed was comfortable "

[](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information)

![Quality Inn & Suites](//images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053_y.jpg)

### Quality Inn & Suites

10/10 Excellent

"Great place. Excellent people. Great service"

[](https://expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information)

![Ramada by Wyndham Santee I-95](//images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6_y.jpg)

### Ramada by Wyndham Santee I-95

10/10 Excellent

"The grounds and property were clean and you could tell they take pride in what they're offering."

[](https://expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information)

## Find out more about Santee

**Everything you need to know about** **Santee** **vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Santee vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santee vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santee vacation rentals we have selected for you start as low as CA $143 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Santee rentals**

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

-   Trending destinations on Expedia.ca
-   All accommodation types in Santee

### Trending destinations on Expedia.ca

-   [Canmore Vacation Rentals](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals)
-   [Maui Vacation Rentals](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
-   [Kelowna Vacation Rentals](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals)
-   [Whistler Vacation Rentals](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals)
-   [Florida Vacation Rentals](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
-   [Victoria Vacation Rentals](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals)
-   [Vancouver Vacation Rentals](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals)
-   [Palm Springs Vacation Rentals](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
-   [Tofino Vacation Rentals](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals)
-   [Calgary Vacation Rentals](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals)
-   [Costa Rica Vacation Rentals](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations)
-   [Vancouver Island Vacation Rentals](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals)
-   [Puerto Vallarta Vacation Rentals](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals)
-   [Hawaii Vacation Rentals](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
-   [Toronto Vacation Rentals](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals)
-   [Banff Vacation Rentals](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals)
-   [Penticton Vacation Rentals](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals)
-   [Osoyoos Vacation Rentals](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals)
-   [Mont Tremblant Vacation Rentals](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals)
-   [Big White Ski Resort Vacation Rentals](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals)
-   [Ontario Vacation Rentals](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations)
-   [British Columbia Vacation Rentals](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
-   [Prince Edward Island Vacation Rentals](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
-   [Québec Vacation Rentals](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

-   [Vacation Homes in Santee](https://expedia.ca/Santee-Private-Vacation-Homes.d9953-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Cottages in Santee](https://expedia.ca/Santee-Cottages.d9953-aaCottages.Travel-Guide-Accommodation)
-   [Motels in Santee](https://expedia.ca/Santee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)
-   [Condo Rentals in Santee](https://expedia.ca/Santee-Condos.d9953-aaCondos.Travel-Guide-Accommodation)
-   [Cabin Rentals in Santee](https://expedia.ca/Santee-Cabins.d9953-aaCabins.Travel-Guide-Accommodation)
-   [Apartments in Santee](https://expedia.ca/Santee-Apartments.d9953-aaApartments.Travel-Guide-Accommodation)
-   [Resorts in Santee](https://expedia.ca/Santee-Resort-Hotels.d9953-aaResortHotels.Travel-Guide-Accommodation)
-   [Aparthotels in Santee](https://expedia.ca/Santee-Apart-Hotels.d9953-aaApartHotels.Travel-Guide-Accommodation)
-   [RV Parks in Santee](https://expedia.ca/Santee-RV-Parks.d9953-aaRVParks.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find vacation rentals in Santee?

> Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

### What are some of the best vacation home rentals in Santee?

> [Wyndham Vacation Resorts Lake Marion](https://www.expedia.ca/Orangeburg-Hotels-Wyndham-Vacation-Resorts-Lake-Marion.h43992569.Hotel-Information): This highly rated vacation home rental in Santee is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a dishwasher, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Santee is [Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](https://www.expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information).

### How many vacation rentals are there in Santee?

> Expedia has 9 vacation rentals for your stay in Santee.

### What can I see and do in Santee?

> While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

### What are vacation rentals like in Santee?

> Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.

### Expedia's Latest Trends

Hotels

-   [Myrtle Beach Golf Hotels](https://expedia.ca/Myrtle-Beach-Hotels-Golf-Hotel.0-0-d601685-tGolfHotel.Travel-Guide-Filter-Hotels)
-   [Myrtle Beach Oceanfront Hotels](https://expedia.ca/Myrtle-Beach-Hotels-Oceanfront-Hotels.0-0-d601685-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
-   [Hotels in Hilton Head Island](https://expedia.ca/Hilton-Head-Island-Hotels.d601684.Travel-Guide-Hotels)
-   [Hotels in North Myrtle Beach](https://expedia.ca/North-Myrtle-Beach-Hotels.d8929.Travel-Guide-Hotels)
-   [Hotels in Columbia](https://expedia.ca/Columbia-Hotels.d764.Travel-Guide-Hotels)
-   [Hotels in Rock Hill](https://expedia.ca/Rock-Hill-Hotels.d6058045.Travel-Guide-Hotels)
-   [Hotels in Charleston](https://expedia.ca/Charleston-Hotels.d179997.Travel-Guide-Hotels)
-   [Myrtle Beach Pet-friendly Hotels](https://expedia.ca/Myrtle-Beach-Hotels-Pet-Friendly-Hotel.0-0-d601685-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Myrtle Beach Adults Only Resorts & Hotels](https://expedia.ca/Myrtle-Beach-Hotels-Adults-Only-Resorts.0-0-d601685-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
-   [Myrtle Beach Hotels with Kitchenettes](https://expedia.ca/Myrtle-Beach-Hotels-Hotels-With-Kitchenettes.0-0-d601685-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
-   [North Myrtle Beach Oceanfront Hotels](https://expedia.ca/North-Myrtle-Beach-Hotels-Oceanfront-Hotels.0-0-d8929-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
-   [Myrtle Beach All Inclusive Resorts and Hotels](https://expedia.ca/Myrtle-Beach-Hotels-All-Inclusive-Hotel.0-0-d601685-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
-   [Myrtle Beach Cheap Hotels](https://expedia.ca/Myrtle-Beach-Hotels-Cheap-Hotels.0-0-d601685-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Hotels in Myrtle Beach](https://expedia.ca/Myrtle-Beach-Hotels.d601685.Travel-Guide-Hotels)
-   [Hilton Head Island All Inclusive Resorts and Hotels](https://expedia.ca/Hilton-Head-Island-Hotels-All-Inclusive-Hotel.0-0-d601684-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)

Flights

-   [Flights to Myrtle Beach](https://expedia.ca/Cheap-Flights-To-Myrtle-Beach.d601685.Travel-Guide-Flights)
-   [Flights to Charleston](https://expedia.ca/Cheap-Flights-To-Charleston.d179997.Travel-Guide-Flights)
-   [Flights to Hilton Head Island](https://expedia.ca/Cheap-Flights-To-Hilton-Head-Island.d601684.Travel-Guide-Flights)
-   [Flights to Columbia](https://expedia.ca/Cheap-Flights-To-Columbia.d764.Travel-Guide-Flights)

Cars

-   [Car rentals in Myrtle Beach](https://expedia.ca/Car-Rentals-In-Myrtle-Beach.d601685.Car-Rental-Guide)

Activities

-   [Things to do in Charleston](https://expedia.ca/Things-To-Do-In-Charleston.d179997.Travel-Guide-Activities)
-   [Things to do in Myrtle Beach](https://expedia.ca/Things-To-Do-In-Myrtle-Beach.d601685.Travel-Guide-Activities)

Packages

-   [Hilton Head Island Vacations](https://expedia.ca/Hilton-Head-Island.d601684.Destination-Travel-Guides)
-   [Charleston Vacations](https://expedia.ca/Charleston.d179997.Destination-Travel-Guides)
-   [Central Vacations](https://expedia.ca/Central.d10503.Destination-Travel-Guides)
-   [Myrtle Beach All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/golf-vacations/601685/Myrtle-Beach)
-   [Myrtle Beach Vacations](https://expedia.ca/Myrtle-Beach.d601685.Destination-Travel-Guides)
-   [Myrtle Beach All-inclusive Vacation Packages](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations/601685/Myrtle-Beach)

Vacation Rentals

-   [Myrtle Beach Rentals](https://expedia.ca/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)

General

-   [Visit Myrtle Beach](https://expedia.ca/Myrtle-Beach.dx601685)

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app

![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFFUlEQVR4Xu3cPXbjOBBFYfg4UNhL4FK4NHJpWoqWMKEDHWNcD4Ufwhh3V9AT2PcmlkoAPmZsyj6d8v9Qmgd/I5BQIKFAQoGEAgkFEgokFEgokFAgoUBCgYQCCQUSCiQUSCiQUCChQEKBhAIJBRIKJBRIKJBQIKFAQoGEGpBnmtrK6Fd+98Gw6iXn+7DqyP/4mtbRTwYBAQEpgZSOfjIIiNb2bLvS9r2O+4nz6KW+r6MWyGIEopYnLkYganniYgSilicuRiBqeeJiBKKWJy5Gf45oe0q3gvS1d5v6wjP1e3zOD/vhiEbXjRYICIj9AAFJICDe10i2E3/Zj3sZfQrEAilDEBAFUgOxQMowhvTRrsXd1Zfe7r7aEAQEBKQEAgISR3p+YuvNbujtUnTirXzSRy0QkAwCMn8AMoxaICDPcoPubfOJX4+mjn4yyGI0dfSTQRajqaOfDLIYTR39ZJDFaOroJ4MsRlNHPxlkMZo6+skDskjbc3meVn6iEjKs+u9AMsjnQKZAMsjnQKa+PfJWTlS6e+9l5F9nj+71G+4P93opFgjIGAgIyFEWWiAg2X517H84fbN3D9s+/jbZetprjfYyuK5K9j24RkMgIBkEBAQEZGhAtN37ODGlzaZnGezDqiP7PX7t2juQvurIICB1I8hm07MM9mHVkUFA6safifjat3arPqftqSEa2SrVN4KAeCAgICAgYaQ1uuMqb7Pp2d62VUc/GQQExKZnewsC0gIB8Q/6ibrHj786HqrIsCrZRg8EJIOAgICA/AmitDbZifbj1e7e+q+1srk+Gt2UtmGjrq6taoGAKBAQEBALJH+F5PywV0f2277SyKqI9bTB9VJ8owcCokBAQDzb6IGA+Np6YlurG7pv32xVG117twXuXgMBAamBgEyBgOT2PH235Tk/CuIJUYYkv5S2ajFqgaT5xMWoBZLmExejFkiaT1yMWiBpPnExaoGk+cTFqAWS5hMXo9aA6O6tW/WuTy4n6u7tI2+vrn+drY0a+b8EWiAJBATEPimBgICMiPduy2726mGvjjK9l/P8xO76qpT0bN5y1wNRICAgIBbIuB1EnXXRx3Z/dWS5e1nwqNv7pahzQNqwBQKSQTIISAIBaQ2jZ1nzYjd0366Rb5e72fQsq5SPrMkdAgEB8VcgIHMgIE+7oX/6Y67mKo3aKttfR0L2Mkr1XwJ1UX8JAgKylxEISFnUX4L8bETd2vS83OOvadXjcmK/uqMPQfoqEJAMAgICMiFzr4aoXYvrdl3KbifOG/vVDYFoBHINZApEI5BrIFPfElmkEz2d+KiH9Qdx5avuFRk3goAsAwEBsUBAnm2Lt9VP6iN2Q/TUvdvAVulEfel9r1tf61YFAgICUtrqJyA1EBCt7X21XY/YY77xXt+DjNtBQEq+8V7fg4zbQUBKvvFe3/8UxLffCpLtG279b1tjbfRmS3UprZvNH/bq6BtAFAhIDQSkbwBRIJ8Qa3ye7qN24mtxNVJyj7oUBAQEBASkBFL7LWLb1Zv9glmrrPrU3Xare3UTCAgICMglEJCvkJ4jubi7ITZypI588Znk6lLaxhYICIgFAgICUrsi1zab2j1+esT22/71hq5fQzuS7Kl7CCSDDOerzaYgYyAZZDhfbTYFGfuWyN8LJBRIKJBQIKFAQoGEAgkFEgokFEgokFAgoUBCgYQCCQUSCiQUSCiQUCChQEKBhAIJBRIKJBRIKJBQIKG+D/Ivi/YnB2uLxLkAAAAASUVORK5CYII=)