Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Vacation Rentals

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Our top choices for Santee vacation rentals

1. LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.8 out of 10, Excellent, (6 reviews)
"Beautiful listing beautiful views. Host very responsive and was quick to take care of any issues. You will enjoy your stay. "
United States
A P C.
The price is CA $247
CA $662 total
includes taxes & fees
Aug 3 - Aug 4
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

2. Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
The price is CA $322
CA $721 total
includes taxes & fees
Aug 9 - Aug 10
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

3. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (97 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
The price is CA $107
CA $123 total
includes taxes & fees
Aug 25 - Aug 26
Bells Marina & Resort

4. Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Yes parking was very easy and everything is very convenient for what we did while we stayed this place is in a perfect location "
United States
James R.
The price is CA $133
CA $302 total
includes taxes & fees
Aug 8 - Aug 9
Country living lake style near Santee

5. Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (34 reviews)
"The place was excellent. The bed was really nice and comfortable. I'd definitely stay again."
United States
Joseph
The price is CA $107
CA $228 total
includes taxes & fees
Aug 3 - Aug 4
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

6. Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very good, (16 reviews)
"Great place to stay. "
United States
Scott J.
The price is CA $107
CA $186 total
includes taxes & fees
Aug 4 - Aug 5
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

7. Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.4 out of 10, Good, (8 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is CA $119
CA $199 total
includes taxes & fees
Aug 4 - Aug 5
Cabin at the lake in Rimini, SC

8. Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (155 reviews)
"Nice place, friendly hosts!"
United States
Dan R.
The price is CA $158
CA $286 total
includes taxes & fees
Aug 3 - Aug 4
Pet friendly country cottage with large fenced-in yard & horses on property

9. Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is CA $175
CA $274 total
includes taxes & fees
Aug 3 - Aug 4
Modern apartment overlooking historic downtown Elloree, SC.

10. Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (14 reviews)
"Great stay!"
United States
Hayden S.
The price is CA $175
CA $226 total
includes taxes & fees
Aug 3 - Aug 4
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

11. 2 Full Beds Non-Smoking

2 Full Beds Non-Smoking
St George, SC
10.0 out of 10, Exceptional, (10 reviews)
The price is CA $118
CA $131 total
includes taxes & fees
Aug 6 - Aug 7
2 Full Beds Non-Smoking

12. Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (23 reviews)
"Amazing "
United States
Fisher R.
The price is CA $175
CA $260 total
includes taxes & fees
Aug 19 - Aug 20
Country Resting Spot just off I95. 12 miles west on hwy 6.

13. Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
10.0 out of 10, Exceptional, (1 review)
"Great quiet and cozy home with a nice backyard and porch with the easy water access by dock. Really enjoyed our stay."
United States
Judith H.
The price is CA $175
CA $620 total
includes taxes & fees
Aug 3 - Aug 4
Turtle Cove - Lake Living on Lake Marion

14. Hobbs Haven at Lake Marion

Hobbs Haven at Lake Marion
Summerton
9.4 out of 10, Exceptional, (13 reviews)
"Great location and host."
United States
Jay M.
The price is CA $161
CA $467 total
includes taxes & fees
Aug 3 - Aug 4
Hobbs Haven at Lake Marion

15. 3-bedroom house in fabulous Summerton next to lake

3-bedroom house in fabulous Summerton next to lake
Summerton
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed our stay at this lovely home! It was the perfect lake getaway for our family and exactly what we were looking for for a relaxing weekend. The home was comfortable, well-kept, and had everything we needed. We made some wonderful memories and would definitely recommend it to others looking for a peaceful place to stay."
United States
Casey L.
3-bedroom house in fabulous Summerton next to lake

16. Orangeburg SC|Queen Bed

Orangeburg SC|Queen Bed
Orangeburg SC
10.0 out of 10, Exceptional, (51 reviews)
"Decent spot for a restful night. Sleep was solid and check in was fast."
United States
Anonymous traveller
The price is CA $113
CA $137 total
includes taxes & fees
Aug 3 - Aug 4
Orangeburg SC|Queen Bed

17. The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
9.4 out of 10, Exceptional, (3 reviews)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
The price is CA $206
CA $355 total
includes taxes & fees
Aug 31 - Sep 1
The Tee Vee Cove is the place to be located near great golfing, fishing and food

18. Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.2 out of 10, Wonderful, (5 reviews)
"A great home and very peaceful!! The host is very friendly and very easy to work with. I recommend this home for a stay 100 percent!!We plan on staying there again when we are in the area, such a great value!!"
United States
Troy K.
The price is CA $208
CA $396 total
includes taxes & fees
Aug 10 - Aug 11
Beautiful brick home w/ large porch and 3 bedrooms

19. Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Eutaw Springs
The price is CA $201
CA $282 total
includes taxes & fees
Aug 4 - Aug 5
Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina

20. Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
8.6 out of 10, Excellent, (4 reviews)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
The price is CA $215
CA $309 total
includes taxes & fees
Aug 3 - Aug 4
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Patio + Pool Table: Lake Marion Getaway: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.